Nemolizumab improved most common symptoms in moderate, severe atopic dermatitis
WASHINGTON – Nemolizumab, an anti-interleukin-31 receptor A monoclonal antibody, was shown to rapidly and consistently improve pruritus, dermatitis, and sleep disturbance in patients with previously uncontrolled moderate-to-severe atopic dermatitis in a phase II, randomized, double-blind,... (Source: Skin and Allergy News)
Source: Skin and Allergy News - March 13, 2016 Category: Dermatology Source Type: news
60 weeks of ixekizumab effective, well tolerated in moderate-to-severe plaque psoriasis
WASHINGTON – After 60 weeks of continuous therapy with the investigational drug ixekizumab, 722 patients who initially had moderate to severe plaque psoriasis had Psoriasis Area Severity Index (PASI) 75, 90, and 100 response rates of 87%, 78%, and 57%, respectively, based on study results presented... (Source: Skin and Allergy News)
Source: Skin and Allergy News - March 10, 2016 Category: Dermatology Source Type: news
Infant egg introduction can prevent sensitization at 12 months
LOS ANGELES – Among infants at risk for allergic disease, egg introduction at 4 months cuts the risk of egg sensitization at 12 months by about half, according a randomized, placebo-controlled, double blind trial from Australia.
“This is what we hoped to find.” Introducing egg early “is certainly... (Source: Skin and Allergy News)
Source: Skin and Allergy News - March 10, 2016 Category: Dermatology Source Type: news
Minimal disease activity criteria in PsA fall short
The minimal disease activity criteria used to identify low disease activity in psoriatic arthritis (PsA) may not be useful as a treatment target in patients with extended skin involvement, according to the results of a small study.
Minimal disease activity (MDA) for PsA is a composite measure... (Source: Skin and Allergy News)
Source: Skin and Allergy News - March 9, 2016 Category: Dermatology Source Type: news
Minimal disease activity criteria in PsA falls short
The minimal disease activity criteria used to identify low disease activity in psoriatic arthritis (PsA) may not be useful as a treatment target in patients with extended skin involvement, according to the results of a small study.
Minimal disease activity (MDA) for PsA is a composite measure... (Source: Skin and Allergy News)
Source: Skin and Allergy News - March 9, 2016 Category: Dermatology Source Type: news
First sublingual immunotherapy tablet for house dust mite allergic rhinitis may be U.S.-bound
LOS ANGELES – A sublingual immunotherapy tablet for house dust mite–induced allergic rhinitis achieved clinically meaningful improvement in symptoms along with less use of rescue medications and a favorable safety profile in a pivotal phase III trial, Dr. Hendrik Nolte reported at the annual... (Source: Skin and Allergy News)
Source: Skin and Allergy News - March 9, 2016 Category: Dermatology Source Type: news
No evidence supports hydrolyzed formula over cows’ milk for allergy prevention
Findings on the use of hydrolyzed formula in place of standard cows’ milk formula to prevent allergy in high-risk infants do not support current guidelines, according to Dr. Robert J Boyle of Imperial College London and his associates.
A review and meta-analysis were performed on 28 randomized... (Source: Skin and Allergy News)
Source: Skin and Allergy News - March 8, 2016 Category: Dermatology Source Type: news
RECIST underestimates benefit of pembrolizumab in subset of melanoma patients
Certain patients with advanced melanoma treated with pembrolizumab had unique response patterns, such as early or delayed tumor pseudoprogression, and Response Evaluation Criteria in Solid Tumors (RECIST) criteria might underestimate the immunotherapy benefit in this subset.
Among 592 patients... (Source: Skin and Allergy News)
Source: Skin and Allergy News - March 7, 2016 Category: Dermatology Source Type: news
Children who have stem cell transplants need skin exams, sun protection
WASHINGTON – Children who have had a hematopoietic stem cell transplant (HSCT) have an increased risk of benign and atypical nevi, Dr. Johanna Sheu reported at the annual meeting of the American Academy of Dermatology.
These patients need to have routine skin exams and be educated about sun... (Source: Skin and Allergy News)
Source: Skin and Allergy News - March 7, 2016 Category: Dermatology Source Type: news
AAAAI: Early peanut consumption brings lasting protection from allergy
LOS ANGELES – A peanut allergy prevention strategy based upon regular consumption of peanut-containing foods from infancy to age 5 continued to provide protection even after peanut intake was halted for a full year from age 5 to 6, according to new results from an extension of the landmark LEAP... (Source: Skin and Allergy News)
Source: Skin and Allergy News - March 7, 2016 Category: Dermatology Source Type: news
Brodalumab met primary endpoints, deaths called ‘unrelated’
The investigational interleukin-17 inhibitor brodalumab met both primary endpoints in a phase III, double-blind, placebo-controlled trial of 661 patients with moderate to severe plaque psoriasis, investigators reported in the British Journal of Dermatology.
By week 12, 83% of patients on 210 mg... (Source: Skin and Allergy News)
Source: Skin and Allergy News - March 7, 2016 Category: Dermatology Source Type: news
Ixekizumab for plaque psoriasis improves work productivity
Ixekizumab improved work productivity among patients with moderate to severe plaque psoriasis in three manufacturer-sponsored phase III clinical trials, according to a report published online March 7 in JAMA Dermatology.
In previous studies, many adults with plaque psoriasis have reported that... (Source: Skin and Allergy News)
Source: Skin and Allergy News - March 7, 2016 Category: Dermatology Source Type: news
Primary care acne treatment reduces dermatology referrals
If primary care physicians initiated therapy in patients with mild to moderate acne, they could significantly decrease referrals to dermatologists, reduce patient waiting times, and cut health care costs, based on a study published online March 6 in JAMA Dermatology.
The researchers used... (Source: Skin and Allergy News)
Source: Skin and Allergy News - March 7, 2016 Category: Dermatology Source Type: news
VIDEO: Study links hair loss in black women with genetics
WASHINGTON – Almost 41% of black women surveyed described hair loss that was consistent with central centrifugal cicatricial alopecia (CCCA), but only about 9% said they had been diagnosed with the condition, Dr. Yolanda Lenzy reported at the annual meeting of the American Academy of Dermatology.... (Source: Skin and Allergy News)
Source: Skin and Allergy News - March 7, 2016 Category: Dermatology Source Type: news
Hemangiomas recur in 25% of infants after propranolol stopped
Infantile hemangiomas treated with propranolol recurred in 25% of children after discontinuation of propranolol in a retrospective study of nearly 1,000 patients, according to findings published online March 7 in Pediatrics.
“Identifying risk factors for rebound growth could affect treatment... (Source: Skin and Allergy News)
Source: Skin and Allergy News - March 7, 2016 Category: Dermatology Source Type: news
