Aggressive approach to photodamaged skin is safe, effective, in small study
BOSTON – A more aggressive approach with fractional radiofrequency treatment of photodamaged facial skin in a single treatment achieved the same results as multiple treatments, with no increase in adverse events, in a small study. “All of these nonablative fractional devices that are out there... (Source: Skin and Allergy News)
Source: Skin and Allergy News - April 26, 2016 Category: Dermatology Source Type: news

Cochrane Review nixes specific allergen immunotherapy for atopic dermatitis
LOS ANGELES – A new Cochrane systematic review and meta-analysis has concluded there is no consistent evidence that specific allergen immunotherapy is beneficial in patients with atopic dermatitis, Dr. Herman H. Tam reported at the annual meeting of the American Academy of Allergy, Asthma, and... (Source: Skin and Allergy News)
Source: Skin and Allergy News - April 23, 2016 Category: Dermatology Source Type: news

Merkel cell carcinoma responds to first-line pembrolizumab
The objective response rate wad 56% among 25 patients... (Source: Skin and Allergy News)
Source: Skin and Allergy News - April 21, 2016 Category: Dermatology Source Type: news

UnitedHealth Group leaving most ACA marketplaces
UnitedHealth Group will not sell policies next year in most of the health insurance marketplaces created by the Affordable Care Act, CEO Stephen Helmsley announced during an April 19 earnings call. “Next year, we will remain in... (Source: Skin and Allergy News)
Source: Skin and Allergy News - April 19, 2016 Category: Dermatology Source Type: news

Pembrolizumab: 33% response rate in advanced melanoma
Immunotherapy with the PD-1 inhibitor pembrolizumab yielded a 33% overall response rate, a 35% progression-free survival rate at 1 year, and a median overall survival of 23 months in 655 patients with advanced melanoma, according to a report published online in JAMA. The agent generally was well... (Source: Skin and Allergy News)
Source: Skin and Allergy News - April 19, 2016 Category: Dermatology Source Type: news

Study found long-term benefit of nivolumab for advanced melanoma patients
One-third of a group of heavily pretreated patients with advanced melanoma who received nivolumab monotherapy were alive 5 years after starting the drug, a phase I trial showed. Survival plateaued at 34% by 48 months, after which time disease control was maintained. “What it does demonstrate is... (Source: Skin and Allergy News)
Source: Skin and Allergy News - April 18, 2016 Category: Dermatology Source Type: news

Most atopic lesions colonized with Staph
Patients with atopic dermatitis are at an increased risk of Staphylococcus aureus colonization of both their lesional and nonlesional skin, as well as their nose, compared with healthy controls, according to a report in the British Journal of Dermatology. Dr. J.E.E. Totté of the department... (Source: Skin and Allergy News)
Source: Skin and Allergy News - April 17, 2016 Category: Dermatology Source Type: news

For BCC, consider curettage only
WAIKOLOA, HAWAII – Curettage alone for the treatment of basal cell carcinomas offers several distinct advantages over the widely accepted technique of curettage followed by electrodessication, Dr. David L. Swanson said at the Hawaii Dermatology Seminar provided by the Global Academy for Medical... (Source: Skin and Allergy News)
Source: Skin and Allergy News - April 16, 2016 Category: Dermatology Source Type: news

Bone marrow transplant cures severe HPV disease in GATA2 immunodeficiency
SAN DIEGO – When genital warts return again and again in women no matter what’s tried, it’s time to think of GATA2 immunodeficiency, according to investigators from the National Institutes of Health, in Bethesda, Md. A bone marrow transplant may prove curative, ending the cycle of vulvectomies... (Source: Skin and Allergy News)
Source: Skin and Allergy News - April 15, 2016 Category: Dermatology Source Type: news

Psoriasis tied to abdominal aortic aneurysm in nationwide study
Patients with severe psoriasis were nearly 70% more likely to develop abdominal aortic aneurysms compared with the general population, according to a Danish population-based cohort study. The findings augment existing evidence linking psoriasis and cardiovascular diseases, wrote Dr. Usman Khalid... (Source: Skin and Allergy News)
Source: Skin and Allergy News - April 14, 2016 Category: Dermatology Source Type: news

How to beat apremilast-induced diarrhea
MAUI, HAWAII – If you’re going to prescribe apremilast for psoriasis or psoriatic arthritis – and more and more physicians are doing so because of the drug’s exceptional safety profile – you’d better get familiar with the oral phosphodiesterase-4 inhibitor’s gastrointestinal side effects, Dr.... (Source: Skin and Allergy News)
Source: Skin and Allergy News - April 13, 2016 Category: Dermatology Source Type: news

Rosacea linked to several autoimmune diseases in women
Rosacea in women is linked with an increased risk for a wide variety of autoimmune disorders including type 1 diabetes, celiac disease, multiple sclerosis, and rheumatoid arthritis, according to a large population-based case-control study. The finding expands the association of rosacea and... (Source: Skin and Allergy News)
Source: Skin and Allergy News - April 13, 2016 Category: Dermatology Source Type: news

Zika caused rash, pruritus more than high fever
Zika virus infection in adults often causes pruritic maculopapular rash, but rarely leads to clinically significant fever, according to two cohort studies in Rio de Janeiro. The findings raise questions about case definitions of Zika virus disease (ZVD). “In our opinion, pruritus, the second... (Source: Skin and Allergy News)
Source: Skin and Allergy News - April 12, 2016 Category: Dermatology Source Type: news

Standard incubation can miss P. acnes in infective endocarditis
AMSTERDAM – Accounting for less than 1% of cases, Propionibacterium acnes has been considered an uncommon cause of infective endocarditis. But data presented at the annual congress of the European Society of Clinical Microbiology and Infectious Diseases suggest that the common anaerobe may... (Source: Skin and Allergy News)
Source: Skin and Allergy News - April 12, 2016 Category: Dermatology Source Type: news

Stick with wheat flour for baked egg and milk challenges
LOS ANGELES – Children who pass oral food challenges to baked egg and milk with wheat flour are at risk for reacting to baked goods made with nonwheat flours, according to a review of more than 200 pediatric food challenges at National Jewish Health in Denver. The children were already known to be... (Source: Skin and Allergy News)
Source: Skin and Allergy News - April 11, 2016 Category: Dermatology Source Type: news