New Mechanism Proposed for Glucose-lowering Effect of Metformin, a Drug for Type 2 Diabetes
Evidence that metformin tampers with glucagon-induced glucose output by disrupting glucagon signaling in liver cells may lead to new type 2 diabetes treatments. (Source: NIDDK News)
Source: NIDDK News - March 15, 2018 Category: Endocrinology Source Type: news
Fending Off Infection in the Urinary Tract
Investigators have begun to characterize the potent, broad-spectrum antimicrobial activity of RNase 7 in the urinary tract during infection. (Source: NIDDK News)
Source: NIDDK News - March 15, 2018 Category: Endocrinology Source Type: news
Treatment To Prevent Hepatitis C Recurrence After Liver Transplantation
In a clinical trial, researchers found that antiviral therapy prior to a liver transplant can prevent hepatitis C recurrence in some patients. (Source: NIDDK News)
Source: NIDDK News - March 15, 2018 Category: Endocrinology Source Type: news
Biliary Atresia Susceptibility Gene Identified in Patients
Researchers identified the GPC1 gene as being potentially lacking in biliary atresia patients. (Source: NIDDK News)
Source: NIDDK News - March 15, 2018 Category: Endocrinology Source Type: news
Gene Mutations Linked to Hypertension
KLHL3 and CUL3 gene mutations in pseudohypoaldosteronism type II suggest further study of the role of these genes in blood pressure/fluid and salt regulation. (Source: NIDDK News)
Source: NIDDK News - March 15, 2018 Category: Endocrinology Source Type: news
Gut Microbes Contribute to Severe Malnutrition in Young Malawian Twins
Finding that dietary deficiency and a certain gut microbial profile caused severe malnutrition may aid in developing interventions for childhood malnutrition. (Source: NIDDK News)
Source: NIDDK News - March 15, 2018 Category: Endocrinology Source Type: news
Working Out the Health Benefits of Autophagy
Autophagy, known to help protect against cancer/other diseases, may help counteract dangerous metabolic consequences of obesity, including type 2 diabetes risk. (Source: NIDDK News)
Source: NIDDK News - March 15, 2018 Category: Endocrinology Source Type: news
Understanding the Genetic Risk for Type 2 Diabetes
Increased understanding of genetic factors that influence type 2 diabetes development may lead to tailored prevention/treatment strategies and new therapies. (Source: NIDDK News)
Source: NIDDK News - March 15, 2018 Category: Endocrinology Source Type: news
Uncovering Genetics Contributing to Diabetes Health Disparities
Studies identify 11 genomic regions that may influence elevated risk of type 2 diabetes in African Americans and South Asians. (Source: NIDDK News)
Source: NIDDK News - March 15, 2018 Category: Endocrinology Source Type: news
Transparent Fish Illuminates Formation of Ductal Network
Zebrafish were used to study development of the liver and of ducts connecting liver, pancreas, intestine; and the role of proteins and genes in these processes. (Source: NIDDK News)
Source: NIDDK News - March 15, 2018 Category: Endocrinology Source Type: news
The Quest To Make Visceral Fat Burn Itself
Studies of brown fat progenitor cells/brown fat development regulation may lead to obesity therapies that cause white fat tissue to behave more like brown fat. (Source: NIDDK News)
Source: NIDDK News - March 15, 2018 Category: Endocrinology Source Type: news
The Double-edged Sword of Hepcidin
Smaller forms of hepcidin lowered serum iron levels in iron overload, and other small compounds reduced hepcidin levels in anemia of chronic inflammation. (Source: NIDDK News)
Source: NIDDK News - March 15, 2018 Category: Endocrinology Source Type: news
Small Molecules Hold Promise to Prevent Type 1 Diabetes
Small molecules show potential in treating autoimmune disease and type 1 diabetes. (Source: NIDDK News)
Source: NIDDK News - March 15, 2018 Category: Endocrinology Source Type: news
Small Molecule Stabilizers as a Potential Treatment for Transthyretin Familial Amyloid Polyneuropathy
Diflunisal and tafamidis identified as small molecule stabilizers with potential to treat transthyretin familial amyloid polyneuropathy (TTR FAP). (Source: NIDDK News)
Source: NIDDK News - March 15, 2018 Category: Endocrinology Source Type: news
Signaling Pathway Found to Regulate Regeneration of Insulin producing β Cells
The adenosine signaling pathway may be important regulator of ? cell regeneration. Promoting ? cell proliferation selectively has potential to treat diabetes. (Source: NIDDK News)
Source: NIDDK News - March 15, 2018 Category: Endocrinology Source Type: news
