Large-scale Human Genetics Study of Fat Depots Identifies Gene Regions Associated with Depot- and Gender-specific Fat Cell Development
The largest-scale human genetics study of its kind has identified seven new gene regions associated with individual variability in body fat. (Source: NIDDK News)
Source: NIDDK News - June 23, 2018 Category: Endocrinology Source Type: news

Donor Outcomes in the Years After Living Donor Liver Transplantation
Studies provide a more complete picture of how living donor liver transplantation affects donors in a myriad of ways. (Source: NIDDK News)
Source: NIDDK News - June 23, 2018 Category: Endocrinology Source Type: news

Identification of Signaling Pathway Involved in Diabetic Nerve Damage Leads to Discovery of Promising New Therapy
Blocking a signaling pathway involved in diabetic nerve damage could prevent or reverse that damage in mice. (Source: NIDDK News)
Source: NIDDK News - June 23, 2018 Category: Endocrinology Source Type: news

Elucidating Complex Interactions Between Human Gut Microbes, Diet, and Response
Research is illuminating the multiple levels of complex interactions that contribute to how human gut microbes affect health. (Source: NIDDK News)
Source: NIDDK News - June 23, 2018 Category: Endocrinology Source Type: news

A Strategy for Synthesizing Potential New Drugs and Research Tools Yields Insights into Fat Cell Development
Researchers developed a set of small chemicals that bind many different proteins in cells and can be used to learn the proteins ’ functions. (Source: NIDDK News)
Source: NIDDK News - June 23, 2018 Category: Endocrinology Source Type: news

Story of Discovery —Intestinal Stem Cells
The discovery of intestinal stem cells, the ancestors to all other cells in the intestinal epithelium, has led to prolific research into the complex dynamics that regulate the development and turnover of the intestinal lining. (Source: NIDDK News)
Source: NIDDK News - June 23, 2018 Category: Endocrinology Source Type: news

Story of Discovery —Artificial Pancreas for Managing Type 1 Diabetes: Cutting-edge Technology 50 Years in the Making
With support from NIDDK, private funding entities, and industry, researchers have created a revolutionary new management tool for type 1 diabetes. (Source: NIDDK News)
Source: NIDDK News - June 23, 2018 Category: Endocrinology Source Type: news

Story of Discovery —APOL1 Gene Variants: Unraveling the Genetic Basis of Elevated Risk for Kidney Disease in African Americans
Identification ofAPOL1 kidney disease genetic risk variants, found primarily in African Americans, is arguably the most important discovery about the pathogenesis of chronic kidney disease over the past few decades. (Source: NIDDK News)
Source: NIDDK News - June 23, 2018 Category: Endocrinology Source Type: news

Immune Molecule Defends Against Bacterial Infection by Withholding Iron
An international group of researchers has found, in a mouse model, one way in which the body thwarts infection by pathogenic bacteria: limiting availability of iron. (Source: NIDDK News)
Source: NIDDK News - June 23, 2018 Category: Endocrinology Source Type: news

New Treatment Prevents Formation of Cystine Stones, a Type of Kidney Stone, in Mice
The antioxidant α-lipoic acid was shown to prevent the formation of cystine stones in mice. (Source: NIDDK News)
Source: NIDDK News - June 23, 2018 Category: Endocrinology Source Type: news

Brain Control of Obesity-related Behaviors
Studies have demonstrated new links between nerve cell activity in specific brain regions and both physical activity and the drive to eat. (Source: NIDDK News)
Source: NIDDK News - June 23, 2018 Category: Endocrinology Source Type: news

Signals from Body Fat to Other Organs —Small Packages with Big Metabolic Impact
Researchers discovered a new way that fat tissue regulates metabolism. (Source: NIDDK News)
Source: NIDDK News - June 23, 2018 Category: Endocrinology Source Type: news

An Appetite-suppressing Hormone in Bones
Researchers discovered that bones secrete a hormone that suppresses appetite and regulates blood glucose levels. (Source: NIDDK News)
Source: NIDDK News - June 23, 2018 Category: Endocrinology Source Type: news

Seeking a Genetic Signature for Urinary Tract Infections
A complex and dynamic interplay betweenE. coli strains and their host environment determines infection and subsequent disease. (Source: NIDDK News)
Source: NIDDK News - June 23, 2018 Category: Endocrinology Source Type: news

Possible New Trigger for Recurrent Urinary Tract Infections Identified
Researchers identified a naturally occurring component of the vaginal microbiota as a possible trigger of recurrent urinary tract infections and a subsequent kidney infection. (Source: NIDDK News)
Source: NIDDK News - June 23, 2018 Category: Endocrinology Source Type: news