Bariatric Surgery in Teens Leads to Relatively Few Short-term Complications
A longitudinal observational study of 242 obese adolescents who had bariatric surgery found 30 days after surgery there were few major or minor complications. (Source: NIDDK News)
Source: NIDDK News - March 15, 2018 Category: Endocrinology Source Type: news

Gut Protein Punches Holes in Bacteria
The body releases a protein, Regllla, that protects the intestinal lining from toxic bacteria by creating tubular structures in the cell wall to kill them. (Source: NIDDK News)
Source: NIDDK News - March 15, 2018 Category: Endocrinology Source Type: news

Nourishing body and mind —effects of maternal diet on brain wiring and metabolism in offspring
Prediabetes and type 2 diabetes in mice offspring fed a high fat diet may be due to changes in the hypothalamus, a part of the brain, during development. (Source: NIDDK News)
Source: NIDDK News - March 15, 2018 Category: Endocrinology Source Type: news

NIH, industry and non-profits join forces to speed validation of disease targets: Goal is to develop new treatments earlier, beginning with Alzheimer ’s, type 2 diabetes, and autoimmune disorders
(Source: NIDDK News)
Source: NIDDK News - March 15, 2018 Category: Endocrinology Source Type: news

Study of a Rare Genetic Disorder of Metabolism Leads to a Promising Therapeutic Approach
Individuals with glycogenesis type XIV, a metabolic disorder that impairs glycoprotein production, can alleviate symptoms by supplementing with sugar galactose. (Source: NIDDK News)
Source: NIDDK News - March 15, 2018 Category: Endocrinology Source Type: news

Story of Discovery: The Diabetes Control and Complications Trial/Epidemiology of Diabetes Interventions And Complications Study
NIDDK funding of long term projects like the Diabetes Control and Complications Trial, has led to discoveries to improve the lives of type 1 diabetes patients. (Source: NIDDK News)
Source: NIDDK News - March 15, 2018 Category: Endocrinology Source Type: news

Story of Discovery: IgA Nephropathy —Shedding Light on a Form of Kidney Disease
Since 1968 researchers have made progress in research on the causes of Immunoglobulin A nephropathy (IgAN), a kidney disorder, but not an effective treatment. (Source: NIDDK News)
Source: NIDDK News - March 15, 2018 Category: Endocrinology Source Type: news

Story of Discovery: Genetic Insights into Pancreatitis
Advancements in identifying trypsin-related genetic factors, and other new genetic variants supported by NIDDK, may lead to better treatments for pancreatitis. (Source: NIDDK News)
Source: NIDDK News - March 15, 2018 Category: Endocrinology Source Type: news

Collaborative Efforts Key to Catalyzing Creation of an Artificial Pancreas
Researchers from around the world attended Workshop on Innovation Towards an Artificial Pancreas to encourage creation of a technological solution to diabetes. (Source: NIDDK News)
Source: NIDDK News - March 15, 2018 Category: Endocrinology Source Type: news

Rare Genetic Mutations that Protect Against Type 2 Diabetes Suggest Possible Approach for Treating the Disease
Challenging prior research, scientists found that rare mutations in the gene SLC30A8 protect against type 2 diabetes, but a more common mutation raises risk. (Source: NIDDK News)
Source: NIDDK News - March 15, 2018 Category: Endocrinology Source Type: news

Design Change May Improve Kidney Stone Treatment
A design change to the lithotripter, a machine that creates shock waves that break up kidney stones, helps to decrease tissue damage and increase effectiveness. (Source: NIDDK News)
Source: NIDDK News - March 15, 2018 Category: Endocrinology Source Type: news

Liver Regeneration Breakthrough Using Mature Human Cells
Scientists reprogrammed mature human fibroblast cells into liver cells, which improved survival of mice in liver failure, a possible transplant alternative. (Source: NIDDK News)
Source: NIDDK News - March 15, 2018 Category: Endocrinology Source Type: news

Animal Model with “Humanized” Liver Predicts Drug Toxicity in Human Livers
A special type of mouse with human cells in its liver helps to predict which experimental drugs can cause liver failure and should thus not be tested in humans. (Source: NIDDK News)
Source: NIDDK News - March 15, 2018 Category: Endocrinology Source Type: news

Structure of blood-clotting receptor identified
P2Y12 receptor plays a key role in blood clotting by communicating with molecules to induce platelet clustering and subsequent thrombus (blood clot) formation. (Source: NIDDK News)
Source: NIDDK News - March 15, 2018 Category: Endocrinology Source Type: news

New Insight into the Mouse Blood Stem Cell Aging Process
Genomic analysis of young and old mouse HSCs suggests how stem cell changes during aging affect HSCs ’ ability to transition into other types of blood cells. (Source: NIDDK News)
Source: NIDDK News - March 15, 2018 Category: Endocrinology Source Type: news