Sitagliptin anti-atherosclerotic effects may be inconsequential
Results of the PROLOGUE study show that the dipeptidyl peptidase-4 inhibitor sitagliptin has no greater effect than other antidiabetic medications on progression of carotid intima-media thickness. (Source: MedWire News)
Source: MedWire News - June 30, 2016 Category: Consumer Health News Tags: Diabetes Source Type: news

Immunotherapy-treated cancer patients may develop rheumatic disorders
Oncologists need to be aware of the potential for rheumatological diseases in patients with cancer following treatment with immune checkpoint inhibitors, say US investigators. (Source: MedWire News)
Source: MedWire News - June 30, 2016 Category: Consumer Health News Tags: Oncology Source Type: news

Omega-3 PUFA biomarkers demonstrate benefits for fatal CHD
Regular consumption of seafood and plant-based omega-3 polyunsaturated fatty acids could help lower the risk of fatal coronary heart disease, confirm findings from a pooled analysis of 19 studies. (Source: MedWire News)
Source: MedWire News - June 30, 2016 Category: Consumer Health News Tags: Coronary heart disease Source Type: news

Unidentified valvular heart disease very common in elderly
Over half of community-living elderly people are likely to have valvular heart disease, show findings of OxVALVE-PCS. (Source: MedWire News)
Source: MedWire News - June 30, 2016 Category: Consumer Health News Tags: Cardiology Source Type: news

Socioeconomic status impacts cardiovascular outcomes in diabetes
Patients with Type 2 diabetes are at a particularly high risk of adverse cardiovascular outcomes if they have low socioeconomic status, a registry study from Sweden shows. (Source: MedWire News)
Source: MedWire News - June 30, 2016 Category: Consumer Health News Tags: Diabetes Source Type: news

Pharmacotherapy reduces conduction system disease risk
Lisinopril therapy significantly reduces incident conduction system disease, indicates a post-hoc analysis of ALLHAT data. (Source: MedWire News)
Source: MedWire News - June 28, 2016 Category: Consumer Health News Tags: Arrhythmia Source Type: news

MOOD-HF supports lack of antidepressant efficacy in HF patients
Escitalopram influences neither depressive symptoms nor medical outcomes when compared with placebo in patients with heart failure and depression, show the MOOD-HF findings. (Source: MedWire News)
Source: MedWire News - June 28, 2016 Category: Consumer Health News Tags: Heart failure Source Type: news

Vitamin D sufficiency linked to better pancreatic cancer survival
Survival is improved in pancreatic cancer patients with sufficient versus deficient plasma levels of 25-hydroxyvitamin D, as assessed prior to diagnosis. (Source: MedWire News)
Source: MedWire News - June 28, 2016 Category: Consumer Health News Tags: Oncology Source Type: news

‘Novel’ analysis addresses antiplatelet benefits in real-world CHD patients
Researchers demonstrate a means of gauging the effects of drugs tested in randomised trials in real-world patients. (Source: MedWire News)
Source: MedWire News - June 27, 2016 Category: Consumer Health News Tags: Coronary heart disease Source Type: news

Elevated troponin I should not rule out donor hearts
Donor cardiac troponin I level is not associated with intermediate-term mortality, cardiac allograft vasculopathy or primary graft failure in patients receiving heart transplants, US researchers report. (Source: MedWire News)
Source: MedWire News - June 27, 2016 Category: Consumer Health News Tags: Heart failure Source Type: news

Pioglitazone effective in diabetes patients with NASH
Pioglitazone may halt the progression of nonalcoholic steatohepatitis in patients with prediabetes or Type 2 diabetes, a randomised trial shows. (Source: MedWire News)
Source: MedWire News - June 27, 2016 Category: Consumer Health News Tags: Diabetes Source Type: news

CYP2C19 gene variants undermine clopidogrel stroke prevention
The first look at CYP2C19 mutations in the context of a randomised controlled trial has confirmed suspicions that they affect the efficacy of clopidogrel in patients with acute stroke. (Source: MedWire News)
Source: MedWire News - June 24, 2016 Category: Consumer Health News Tags: Stroke Source Type: news

Race impacts adverse outcomes in atrial fibrillation
Black individuals with atrial fibrillation have markedly higher rates of stroke, heart failure, coronary heart disease and mortality than their White counterparts, data from the Atherosclerosis Risk in Communities study show. (Source: MedWire News)
Source: MedWire News - June 24, 2016 Category: Consumer Health News Tags: Arrhythmia Source Type: news

Study highlights lack of guidance on deintensifying diabetic regimens
Patients with Type 2 diabetes often receive unnecessarily intensive treatment for long durations, increasing their risk of severe hypoglycaemia, research shows. (Source: MedWire News)
Source: MedWire News - June 24, 2016 Category: Consumer Health News Tags: Diabetes Source Type: news

Potential increase in PD incidence reported
A study in Minnesota, USA, has found an increase in the incidence of parkinsonism and Parkinson’s disease over the past 30 years that may be related to the dramatic reduction in smoking behaviour in the second half of the 20th century or other lifestyle or environmental changes. (Source: MedWire News)
Source: MedWire News - June 24, 2016 Category: Consumer Health News Tags: Parkinson ' s disease Source Type: news