Mixed results in palonosetron, granisetron head-to-head trial
The findings of a phase III trial pitting a second- against a first-generation 5-hydroxytryptamine 3 receptor antagonist suggest that choosing the appropriate 5-HT3 inhibitor as part of a triplet regimen to prevent chemotherapy-induced nausea and vomiting may not be straightforward. (Source: MedWire News)
Source: MedWire News - July 6, 2016 Category: Consumer Health News Tags: Oncology Source Type: news
Accelerated cardiovascular risk in patients with FH phenotype
Patients with levels of low-density lipoprotein cholesterol normally seen in familial hypercholesterolaemia have the cardiovascular risk of someone decades older than they are, shows a population-based study. (Source: MedWire News)
Source: MedWire News - July 4, 2016 Category: Consumer Health News Tags: Cardiometabolic Source Type: news
Cardiac troponin test refines ACS rule-out process
Testing high-sensitivity cardiac troponin T levels in patients with acute coronary syndromes reduces their need for cardiac stress testing and speeds their discharge from the emergency department, report researchers. (Source: MedWire News)
Source: MedWire News - July 4, 2016 Category: Consumer Health News Tags: Acute coronary syndromes Source Type: news
First-line nivolumab promising in advanced NSCLC
Phase I results published in the Journal of Clinical Oncology suggest that nivolumab, either given alone or alongside platinum-based doublet chemotherapy, could have a role in the first-line treatment of advanced non-small-cell lung cancer. (Source: MedWire News)
Source: MedWire News - July 4, 2016 Category: Consumer Health News Tags: Non-small-cell lung cancer Source Type: news
Circulating angiogenic factor shows PAH biomarker potential
Hepatoma-derived growth factor predicts disease severity and survival in patients with pulmonary arterial hypertension, showing some possible clinical advantages over N-terminal pro-brain natriuretic peptide, researchers report. (Source: MedWire News)
Source: MedWire News - July 4, 2016 Category: Consumer Health News Tags: Pulmonary hypertension Source Type: news
TDF reduces vertical HBV transmission
The mother-to-child transmission of hepatitis B virus is reduced with tenofovir disoproxil fumarate treatment during the third trimester in pregnant chronic HBV patients with a high viral load, show the findings of a trial conducted in China. (Source: MedWire News)
Source: MedWire News - July 4, 2016 Category: Consumer Health News Tags: HBV Source Type: news
FIB-4 index predicts HBV-related HCC
Japanese researchers reveal an association between elevated FIB-4 index 24 weeks after the initiation of nucleos(t)ide analogue therapy and the development of hepatocellular carcinoma in patients with chronic hepatitis B virus infection. (Source: MedWire News)
Source: MedWire News - July 4, 2016 Category: Consumer Health News Tags: HBV Source Type: news
Infant HBV vaccination prevents HCC in children, young adults
Immunisation against hepatitis B virus in infants protects against the development of hepatocellular carcinoma in not only children but also young adults, a Taiwanese study finds. (Source: MedWire News)
Source: MedWire News - July 4, 2016 Category: Consumer Health News Tags: HBV Source Type: news
Neoadjuvant endocrine therapy ‘a reasonable option’ for ER-positive breast cancer
Endocrine therapy should be reconsidered as a potential option in the neoadjuvant setting for localised oestrogen receptor-positive breast cancer, say the authors of a meta-analysis. (Source: MedWire News)
Source: MedWire News - July 1, 2016 Category: Consumer Health News Tags: Breast cancer Source Type: news
‘Comprehensive’ management approach needed for AF
Death is a bigger risk than stroke among patients with atrial fibrillation, particularly during the first 4 months after diagnosis, research shows. (Source: MedWire News)
Source: MedWire News - July 1, 2016 Category: Consumer Health News Tags: Arrhythmia Source Type: news
Radial access gains ground over femoral route for PCI
A meta-analysis supports that radial access delivers better outcomes and improved safety than femoral access in patients undergoing percutaneous coronary intervention. (Source: MedWire News)
Source: MedWire News - July 1, 2016 Category: Consumer Health News Tags: Interventional cardiology Source Type: news
Virtual reality games fail to outplay card and ball games in stroke rehabilitation
Researchers have found inexpensive recreational activities such as playing cards or ball games are as effective add-on therapies to conventional stroke rehabilitation as virtual reality interventions. (Source: MedWire News)
Source: MedWire News - June 30, 2016 Category: Consumer Health News Tags: Stroke Source Type: news
ALK fusion variants could influence NSCLC crizotinib response
In non-small-cell lung cancer patients with anaplastic lymphoma kinase rearrangement treated with crizotinib, progression-free survival varies according to the ALK fusion variant. (Source: MedWire News)
Source: MedWire News - June 30, 2016 Category: Consumer Health News Tags: Non-small-cell lung cancer Source Type: news
BP effects on vasculature begin below hypertensive threshold
Higher systolic blood pressure is associated with increased carotid intima-media thickness even within the normotensive range, research shows. (Source: MedWire News)
Source: MedWire News - June 30, 2016 Category: Consumer Health News Tags: Hypertension Source Type: news
No CVD gain for elderly individuals in physical activity programme
Participation in a long-term moderately intense activity programme has failed to reduce cardiovascular disease events in older adults, findings from the LIFE Study show. (Source: MedWire News)
Source: MedWire News - June 30, 2016 Category: Consumer Health News Tags: Cardiology Source Type: news
