Aspirin resistance signals increased stroke severity
Stroke severity and infarct volume are significantly increased among patients who become resistant to aspirin, show study findings published in Neurology. (Source: MedWire News)
Source: MedWire News - April 13, 2016 Category: Consumer Health News Tags: Stroke Source Type: news
TDF, entecavir duo ‘highly effective’ for difficult-to-treat chronic HBV
The combination of tenofovir disoproxil fumarate and entecavir induces a high rate of viral suppression in patients with chronic hepatitis B virus infection who have failed multiple nucleos(t)ide analogue regimens, phase IIIb results indicate. (Source: MedWire News)
Source: MedWire News - April 13, 2016 Category: Consumer Health News Tags: HBV Source Type: news
HLA-C/KIR genotype linked to HBeAg-positive HBV interferon response
The human leucocyte antigen-C and killer immunoglobin-like receptor genotypes are associated with response to interferon-based therapy in patients with chronic hepatitis B virus infection positive for hepatitis B e antigen, say researchers. (Source: MedWire News)
Source: MedWire News - April 13, 2016 Category: Consumer Health News Tags: HBV Source Type: news
Dynamic HBsAg measurements predict HBV inactivity
In patients with hepatitis B e antigen-negative chronic hepatitis B virus infection, repeated measurement of hepatitis B surface antigen during long-term follow-up can help identify those with inactive virus, suggests a chart review. (Source: MedWire News)
Source: MedWire News - April 13, 2016 Category: Consumer Health News Tags: HBV Source Type: news
Minimally important dyspnoea, fatigue changes in PAH patients defined
Researchers say that a change of around 1 unit in Borg dyspnoea or fatigue scores signifies an important change in patients with pulmonary arterial hypertension. (Source: MedWire News)
Source: MedWire News - April 13, 2016 Category: Consumer Health News Tags: Pulmonary hypertension Source Type: news
Prognostic markers expanded for AD, ALS
Two studies expand the range of putative prognostic markers for neurological disease, with creatinine kinase found to be prognostic in amyotrophic lateral sclerosis and neurogranin offering diagnostic and prognostic potential in Alzheimer’s disease. (Source: MedWire News)
Source: MedWire News - April 12, 2016 Category: Consumer Health News Tags: Neurology Source Type: news
BMPR2 mutations affect outcomes of PAH patients
Mutations in the bone morphogenetic protein receptor type II gene affect not only the risk of developing pulmonary arterial hypertension but also the severity and outcomes of the disease, shows a meta-analysis of individual patient data. (Source: MedWire News)
Source: MedWire News - April 12, 2016 Category: Consumer Health News Tags: Pulmonary hypertension Source Type: news
Increased BMP7 levels predict PAH mortality
Elevated levels of circulating bone morphogenetic protein 7 are associated with an increased mortality risk in patients with pulmonary arterial hypertension, find Chinese researchers. (Source: MedWire News)
Source: MedWire News - April 12, 2016 Category: Consumer Health News Tags: Pulmonary hypertension Source Type: news
In brief: Prognostic markers expanded for AD, ALS
Two studies expand the range of putative prognostic markers for neurological disease, with creatinine kinase found to be prognostic in amyotrophic lateral sclerosis and neurogranin offering diagnostic and prognostic potential in Alzheimer’s disease. (Source: MedWire News)
Source: MedWire News - April 12, 2016 Category: Consumer Health News Source Type: news
Translational study identifies novel AD target
Cell surface heparan sulfates, which are found on all cells including neurons, have become the latest putative target to combat Alzheimer’s disease. (Source: MedWire News)
Source: MedWire News - April 12, 2016 Category: Consumer Health News Tags: Alzheimer ' s disease Source Type: news
Zonisamide relieves myoclonus dystonia motor symptoms
A randomised crossover trial shows that zonisamide significantly improves motor symptoms and related disability in adults with myoclonus dystonia. (Source: MedWire News)
Source: MedWire News - April 12, 2016 Category: Consumer Health News Tags: Movement disorders Source Type: news
Rituximab shows second-line promise in autoimmune limbic encephalitis
Rituximab is an effective and well-tolerated second-line treatment for patients with autoimmune limbic encephalitis, suggests research. (Source: MedWire News)
Source: MedWire News - April 7, 2016 Category: Consumer Health News Tags: Neurology Source Type: news
APO866 lacks efficacy in cutaneous T-cell lymphoma
The nicotinamide adenine dinucleotide biosynthesis inhibitor APO866 does not show efficacy in patients with cutaneous T-cell lymphoma, according to phase II trial results reported in JAMA Dermatology. (Source: MedWire News)
Source: MedWire News - April 7, 2016 Category: Consumer Health News Tags: Lymphoma Source Type: news
Ovarian cancer HRQoL ‘not compromised’ with trebananib
Treatment with the antiangiogenesis inhibitor trebananib does not adversely affect health-related quality of life in patients with recurrent ovarian cancer, suggests the placebo-controlled TRINOVA-1 trial. (Source: MedWire News)
Source: MedWire News - April 7, 2016 Category: Consumer Health News Tags: Oncology Source Type: news
