Immune modulation may be key to ω-3 CRC chemoprevention
The anticancer effects of marine ω-3 polyunsaturated fatty acids may differ by tumour immune subtypes, say researchers who show that high ω-3 intake reduces the risk of colorectal cancer with high, but not low, density of FOXP3+ regulatory T cells. (Source: MedWire News)
Source: MedWire News - May 6, 2016 Category: Consumer Health News Tags: Colorectal cancer Source Type: news

Majority of radiotherapy trials remain unpublished
Compliance with the mandatory requirement in the USA to publish the results of clinical trials is poor, shows research presented at the 35th ESTRO conference held in Turin, Italy. (Source: MedWire News)
Source: MedWire News - May 6, 2016 Category: Consumer Health News Tags: Oncology Source Type: news

More evidence for combination therapy benefits in PAH
Another meta-analysis adds to evidence of increased benefits for patients with pulmonary arterial hypertension who are given combination therapy. (Source: MedWire News)
Source: MedWire News - May 6, 2016 Category: Consumer Health News Tags: Pulmonary hypertension Source Type: news

Pulmonary hypertension impacts walking ability in SSc patients
The results of a meta-analysis show the adverse impact pulmonary hypertension has on the walking stamina of patients with systemic sclerosis. (Source: MedWire News)
Source: MedWire News - May 6, 2016 Category: Consumer Health News Tags: Pulmonary hypertension Source Type: news

Mixed picture for diabetes mortality trends
A large registry analysis shows that younger people may be missing out on a general decline in mortality rates among patients with diabetes. (Source: MedWire News)
Source: MedWire News - May 6, 2016 Category: Consumer Health News Tags: Diabetes Source Type: news

Newborn screen for Niemann–Pick disease type C ready for piloting
Researchers have developed a bile acid-based test that they believe could help screen for Niemann–Pick disease type C in newborns. (Source: MedWire News)
Source: MedWire News - May 5, 2016 Category: Consumer Health News Tags: Neurology Source Type: news

Real risk of rebound syndrome following fingolimod cessation for MS
Rebound syndrome following cessation of fingolimod for multiple sclerosis occurs at a clinically relevant rate, shows research, prompting the need for further study on how best to sequence and discontinue such drugs. (Source: MedWire News)
Source: MedWire News - May 4, 2016 Category: Consumer Health News Tags: Multiple sclerosis Source Type: news

Caution urged with add-on DPP-4 inhibitors
Physicians should be aware of the need to reduce the dose of sulphonylureas when adding dipeptidyl peptidase-4 inhibitor treatment in patients with Type 2 diabetes, say the authors of a meta-analysis. (Source: MedWire News)
Source: MedWire News - May 4, 2016 Category: Consumer Health News Tags: Diabetes Source Type: news

Mental disorder risk increase begins at cancer diagnosis workup
Research in JAMA Oncology highlights the need for psychological management and support as early during the course of cancer as the initial workup leading to a diagnosis. (Source: MedWire News)
Source: MedWire News - May 4, 2016 Category: Consumer Health News Tags: Oncology Source Type: news

NSCLC MAGE-A3 immunotherapy development halted
Disease-free survival is not prolonged with adjuvant MAGE-A3 immunotherapy in patients with surgically resected non-small-cell lung cancer, according to a placebo-controlled trial. (Source: MedWire News)
Source: MedWire News - May 4, 2016 Category: Consumer Health News Tags: Non-small-cell lung cancer Source Type: news

Cerebellar not cerebral atrophy predicts poor anti-NMDAR encephalitis outcome
Diffuse cerebral atrophy in patients with anti-N-methyl-D-aspartate receptor encephalitis does not necessarily mean irreversible brain damage, whereas progressive cerebellar atrophy may indicate a poor long-term prognosis, researchers report. (Source: MedWire News)
Source: MedWire News - May 3, 2016 Category: Consumer Health News Tags: Neurology Source Type: news

Viral link to Type 1 diabetes bolstered
A research letter in JAMA supports a link between viral infections in infancy and the development of Type 1 diabetes. (Source: MedWire News)
Source: MedWire News - May 3, 2016 Category: Consumer Health News Tags: Diabetes Source Type: news

Anthracycline-related cognitive dysfunction concerns disputed
The authors of a research letter find no association between anthracycline-based chemotherapy and decline in neurocognitive function among breast cancer survivors, in contrast to another recent study. (Source: MedWire News)
Source: MedWire News - April 29, 2016 Category: Consumer Health News Tags: Breast cancer Source Type: news

Neighbourhood deprivation link to diabetes strengthened
A large study based on a policy of semi-randomised dispersal of refugees within a country supports the notion that living in a deprived neighbourhood can increase people’s risk of developing Type 2 diabetes. (Source: MedWire News)
Source: MedWire News - April 29, 2016 Category: Consumer Health News Tags: Diabetes Source Type: news

Disrupted memory pathways uncovered in epilepsy patients
A study in rats, backed up by results in patients, has revealed how interictal epileptiform discharges may lead to memory impairments in patients with epilepsy. (Source: MedWire News)
Source: MedWire News - April 29, 2016 Category: Consumer Health News Tags: Epilepsy Source Type: news