Maternal pregabalin exposure linked to major birth defect risk
First trimester exposure to pregabalin may be associated with an increased risk of major birth defects, an observational study suggests. (Source: MedWire News)
Source: MedWire News - May 19, 2016 Category: Consumer Health News Tags: Neurology Source Type: news

Early aspirin benefits after minor stroke ‘underestimated’
A meta-analysis of individual patient data has thrown light on the benefits of aspirin for secondary prevention in patients with ischaemic stroke. (Source: MedWire News)
Source: MedWire News - May 19, 2016 Category: Consumer Health News Tags: Stroke Source Type: news

Raised lipoprotein(a) could account for a quarter of FH cases
High levels of lipoprotein(a) could account for a substantial proportion of cases of familial hypercholesterolaemia, a large study shows. (Source: MedWire News)
Source: MedWire News - May 19, 2016 Category: Consumer Health News Tags: Cardiometabolic Source Type: news

Strategy choice impacts long-term mortality in bifurcation stenting
Using a provisional rather than a planned two-stent strategy for coronary bifurcation stenting may halve long-term mortality, pooled study data show. (Source: MedWire News)
Source: MedWire News - May 19, 2016 Category: Consumer Health News Tags: Coronary heart disease Source Type: news

Call for improvements in CVD risk models
There are too many poorly validated models for predicting cardiovascular disease risk in the general population, researchers report in The BMJ. (Source: MedWire News)
Source: MedWire News - May 19, 2016 Category: Consumer Health News Tags: Cardiology Source Type: news

CML treatment-free remission criteria outlined
Treatment-free remission may be feasible in many patients with chronic myeloid leukaemia, say researchers who set out clinical and logistical requirements for discontinuing tyrosine kinase inhibitor therapy. (Source: MedWire News)
Source: MedWire News - May 18, 2016 Category: Consumer Health News Tags: Chronic myeloid leukaemia Source Type: news

EPIC Results Shed Light On First-Line Ponatinib Risk–Benefit Profile
The primary endpoint of major molecular response at 12 months for ponatinib versus imatinib in patients with newly diagnosed chronic phase–chronic myeloid leukaemia remains undetermined, report the EPIC trial investigators. (Source: MedWire News)
Source: MedWire News - May 18, 2016 Category: Consumer Health News Tags: Chronic myeloid leukaemia Source Type: news

Antihypertensive initiation, intensification linked to raised short-term fall risk
Older patients initiating or intensifying antihypertensive medication have a short-term increased risk of sustaining a serious fall injury, US study findings indicate. (Source: MedWire News)
Source: MedWire News - May 18, 2016 Category: Consumer Health News Tags: Hypertension Source Type: news

Targeting rotors challenged for nonparoxsymal AF
Targeted ablation of electrical rotors and focal sources is not a successful strategy in patients with persistent or long-standing atrial fibrillation, shows the randomised OASIS trial. (Source: MedWire News)
Source: MedWire News - May 18, 2016 Category: Consumer Health News Tags: Arrhythmia Source Type: news

Real-world CML management in line with ELN guidelines
The first-line treatment and monitoring of patients with chronic phase–chronic myeloid leukaemia is in accordance with the European LeukaemiaNet recommendations, finds a real-world clinical practice study. (Source: MedWire News)
Source: MedWire News - May 18, 2016 Category: Consumer Health News Tags: Chronic myeloid leukaemia Source Type: news

Allogeneic HSCT offers good survival for select TKI-refractory CML patients
Allogeneic hematopoietic stem cell transplantation is associated with a high rate of survival for carefully chosen chronic myeloid leukaemia patients who do not respond well to tyrosine kinase inhibitor therapy, research suggests. (Source: MedWire News)
Source: MedWire News - May 18, 2016 Category: Consumer Health News Tags: Chronic myeloid leukaemia Source Type: news

Maintaining fitness wards off diabetes
Young adults who maintain good fitness levels into middle age reduce their risk of developing diabetes, irrespective of changes in their body mass index, show findings from the CARDIA study. (Source: MedWire News)
Source: MedWire News - May 18, 2016 Category: Consumer Health News Tags: Diabetes Source Type: news

Early high-dose rhEPO fails to improve neurodevelopment in very preterm infants
Very preterm infants do not gain protection against neurodevelopmental delay with early prophylactic high-dose recombinant human erythropoietin, researchers report. (Source: MedWire News)
Source: MedWire News - May 18, 2016 Category: Consumer Health News Tags: Neurology Source Type: news

Memory test offers clue to pathological diagnosis in primary progressive aphasia
Patients with primary progressive aphasia show selective vulnerabilities in effortless learning and delayed retrieval of verbal information if their syndrome is related to Alzheimer’s disease rather than frontotemporal lobar degeneration, research indicates. (Source: MedWire News)
Source: MedWire News - May 17, 2016 Category: Consumer Health News Tags: Alzheimer ' s disease Source Type: news

Many biomarkers for PD fail to inform on progression
Longitudinal monitoring of 30 tests for marker candidates in early Parkinson’s disease has found that just 10 show significant changes commensurate with disease progression. (Source: MedWire News)
Source: MedWire News - May 16, 2016 Category: Consumer Health News Tags: Parkinson ' s disease Source Type: news