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New study provides data on protections of ebola vaccines
This study identifies features of the antibody response responsible for survival from 139 immune- and vaccine-related parameters.* Findings will help develop vaccines that produce an antibody response profile which ensures protection and focuses on survival quality (Source: EurekAlert! - Infectious and Emerging Diseases)
Source: EurekAlert! - Infectious and Emerging Diseases - July 14, 2021 Category: Infectious Diseases Source Type: news

Primary care provides clinical guidance, answers about COVID-19 testing, vaccine
(American Academy of Family Physicians) Primary care physicians have played a crucial role in vaccination delivery to the U.S. population, including the elderly. They are well positioned to help with administering COVID-19 vaccinations. They are also equipped to provide clinical guidance to help patients interpret results from COVID-19 testing and immunity determinations and can answer vaccine questions (Source: EurekAlert! - Infectious and Emerging Diseases)
Source: EurekAlert! - Infectious and Emerging Diseases - July 14, 2021 Category: Infectious Diseases Source Type: news

July/August 2021 Annals of Family Medicine tip sheet
(American Academy of Family Physicians) Annals of Family Medicine is a peer-reviewed, indexed research journal that provides a cross-disciplinary forum for new, evidence-based information affecting the primary care disciplines. (Source: EurekAlert! - Infectious and Emerging Diseases)
Source: EurekAlert! - Infectious and Emerging Diseases - July 14, 2021 Category: Infectious Diseases Source Type: news

Short chain fatty acids: An 'ace in the hole' against SARS-CoV-2 infection
(University of Fukui) SARS-CoV-2, the virus responsible for the COVID-19 pandemic, is highly transmissible, with nasal passages being the target of original infection. The nasal passage also shows the highest expression of ACE2, a protein that has been widely linked with increased susceptibility to COVID-19. Now, scientists from Japan have found that nasal inflammation can influence susceptibility to SARS-CoV-2. They also identified the use of short chain fatty acids as a potential COVID-19 management strategy. (Source: EurekAlert! - Infectious and Emerging Diseases)
Source: EurekAlert! - Infectious and Emerging Diseases - July 14, 2021 Category: Infectious Diseases Source Type: news

Early perceptions of COVID-19 in Pennsylvania
(American Academy of Family Physicians) A survey conducted in March 2020 reports that early concern for COVID-19 outmatched concern for influenza, but respondents may have been less focused on their perceived likelihood of contracting COVID-19 and more concerned with its severe impact on their health. (Source: EurekAlert! - Infectious and Emerging Diseases)
Source: EurekAlert! - Infectious and Emerging Diseases - July 14, 2021 Category: Infectious Diseases Source Type: news

USGS-led study helps in the fight against the coronavirus pandemic
(US Geological Survey) With few additional targeted tests and non-invasive surveys, public health agencies can better estimate disease occurrence and trends, changes in transmission, rates of hospitalization and death and effectiveness of vaccines and other control measures. (Source: EurekAlert! - Infectious and Emerging Diseases)
Source: EurekAlert! - Infectious and Emerging Diseases - July 14, 2021 Category: Infectious Diseases Source Type: news

Role of subnuclear NSrp70 in immunity-studied at Gwangju Institute of Science & Technology
(GIST (Gwangju Institute of Science and Technology)) T cells are components of the body's immune system. The ability of T cells to recognize diverse pathogens and mount a defense against them stems from the way proteins are spliced during their development and maturation. Now, scientists from Korea highlight the importance of a protein called NSrp70, which was previously discovered in T cell subnuclear spaces, in regulating the maturation of these cells, and has implications in T cell-mediated adaptive immunity against viral infection and cancer. (Source: EurekAlert! - Infectious and Emerging Diseases)
Source: EurekAlert! - Infectious and Emerging Diseases - July 14, 2021 Category: Infectious Diseases Source Type: news

Allocating COVID-19 vaccines based on health and socioeconomics could reduce mortality
(PLOS) COVID-19 vaccination strategies in the United States are informed by individual characteristics such as age and occupation. A study published in the open access journal PLOS Medicine by Sasikiran Kandula and Jeffrey Shaman of Columbia University, New York, United States suggests that including socioeconomic indicators as prioritization criteria for vaccination may help minimize severe outcomes, particularly deaths. (Source: EurekAlert! - Infectious and Emerging Diseases)
Source: EurekAlert! - Infectious and Emerging Diseases - July 13, 2021 Category: Infectious Diseases Source Type: news

Allocating COVID vaccines based on health and socioeconomic factors could cut mortality
(Columbia University's Mailman School of Public Health) An estimated 43 percent of variability in U.S. COVID-19 mortality is linked with county-level socioeconomic indicators and health vulnerabilities, with the strongest association seen in the proportions of people living with chronic kidney disease and living in nursing homes. The study by Columbia University Mailman School of Public Health researchers suggests that allocating vaccines based on these factors could help minimize severe outcomes, particularly deaths. Results are published in the open-access journal PLOS Medicine. (Source: EurekAlert! - Infectious and Emerging Diseases)
Source: EurekAlert! - Infectious and Emerging Diseases - July 13, 2021 Category: Infectious Diseases Source Type: news

Clinical characterization, prediction of severity of SARS-CoV-2 infection among US adults
(JAMA Network) What The Study Did: Researchers used a large data resource of U.S. COVID-19 cases and control patients who tested negative from multiple health systems across the country to evaluate COVID-19 severity and risk factors over time and assess the use of machine learning to predict clinical severity. (Source: EurekAlert! - Infectious and Emerging Diseases)
Source: EurekAlert! - Infectious and Emerging Diseases - July 13, 2021 Category: Infectious Diseases Source Type: news

GARDP, CHAI and Shionogi announce MOU to increase access to antibiotic
(Global Antibiotic Research& Development Partnership) The Global Antibiotic Research and Development Partnership (GARDP), the Clinton Health Access Initiative (CHAI) and Shionogi& Co., Ltd today announced a Memorandum of Understanding (MOU) to accelerate access, including in low- and middle-income countries, to the antibiotic cefiderocol for bacterial infections in patients with limited treatment options. (Source: EurekAlert! - Infectious and Emerging Diseases)
Source: EurekAlert! - Infectious and Emerging Diseases - July 13, 2021 Category: Infectious Diseases Source Type: news

Highlighting the effectiveness of the COVID-19 vaccines could hold key to converting doubters
(University of Bristol) Informing people about how well the new COVID-19 vaccines work could boost uptake among doubters substantially, according to new research. (Source: EurekAlert! - Infectious and Emerging Diseases)
Source: EurekAlert! - Infectious and Emerging Diseases - July 13, 2021 Category: Infectious Diseases Source Type: news

Supermarket model to guide safer shopping amid pandemic
(Skolkovo Institute of Science and Technology (Skoltech)) Skoltech team has developed a model for assessing infection risks for supermarket customers. The researchers believe that their model will help formulate scientifically backed rules for safe shopping during the pandemic. Curiously enough, the team discovered that increasing customer density has only a slight positive effect on sales, so filling the store to the limit makes little sense not just epidemiologically but economically, too. (Source: EurekAlert! - Infectious and Emerging Diseases)
Source: EurekAlert! - Infectious and Emerging Diseases - July 13, 2021 Category: Infectious Diseases Source Type: news

COVID-causing coronavirus following predictable mutational footsteps
(University of Nebraska-Lincoln) New research from the University of Nebraska-Lincoln has shown that the mutations arising in the COVID-19-causing SARS-CoV-2 virus seem to run in the family -- or at least the genus of coronaviruses most dangerous to humans. After comparing the early evolution of SARS-CoV-2 against that of its closest relatives, the betacoronaviruses, the Nebraska team found that SARS-CoV-2 mutations are occurring in essentially the same locations, both genetically and structurally. (Source: EurekAlert! - Infectious and Emerging Diseases)
Source: EurekAlert! - Infectious and Emerging Diseases - July 13, 2021 Category: Infectious Diseases Source Type: news

Study: Racial/ethnic and language inequities in ways patients obtain COVID-19 testing
(University of Minnesota) A recent study from researchers at the University of Minnesota and Hennepin Healthcare Research Institute is among the first to examine how different socio-demographic groups used telehealth, outpatient (i.e., clinic), emergency department and inpatient (i.e., hospital) care to test for SARS-CoV-2, the virus that causes COVID-19. (Source: EurekAlert! - Infectious and Emerging Diseases)
Source: EurekAlert! - Infectious and Emerging Diseases - July 13, 2021 Category: Infectious Diseases Source Type: news