Oncotarget: Prostate cancer and a possible link with schizophrenia
(Impact Journals LLC) The importance of complex networks of heterotypic interactions between multiple distinct cell types (both malignant and normal) and regulatory circuits has now become widely recognized. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - June 11, 2021 Category: Cancer & Oncology Source Type: news

Nearly S$10 million awarded to research on deadly brain cancer
(SingHealth) Glioblastoma (GBM) is a highly aggressive type of brain cancer. Even with current standard of care, 50% of patients die within 15 months of diagnosis. With a national grant of about S$10 million, researchers in Singapore are working with overseas collaborators to address these challenges and develop new diagnostic and treatment options so patients can receive effective targeted therapy. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - June 11, 2021 Category: Cancer & Oncology Source Type: news

UCSF launches $250M initiative to develop living therapeutics
(University of California - San Francisco) UC San Francisco is launching a new initiative to propel the development of living therapeutics -- a category of treatments broadly defined as human and microbial living cells that are selected, modified, or engineered to treat or cure disease - and bring them quickly to patients. The Living Therapeutics Initiative (LTI) will bring together UCSF's vast scientific and clinical expertise to accelerate research and quickly advance promising therapies to clinical trials for patients who have few, if any, good treatment options. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - June 10, 2021 Category: Cancer & Oncology Source Type: news

COVID-19 vaccine hesitancy among patients with breast cancer
(JAMA Network) This survey study among women with breast cancer in Mexico evaluates their specific concerns about and high hesitancy rate toward COVID-19 vaccination. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - June 10, 2021 Category: Cancer & Oncology Source Type: news

Combination targeted therapy provides durable remission for patients with CLL
(University of Texas M. D. Anderson Cancer Center) A combination of ibrutinib and venetoclax was found to provide lasting disease remission in patients with newly diagnosed chronic lymphocytic leukemia (CLL), according to researchers at The University of Texas MD Anderson Cancer Center. Findings from the single-institution Phase II study were published today in JAMA Oncology and provide the longest follow-up data on patients treated with this drug regimen. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - June 10, 2021 Category: Cancer & Oncology Source Type: news

Astronomy meets pathology to identify predictive biomarkers for cancer immunotherapy
(Johns Hopkins Medicine) Pairing sky-mapping algorithms with advanced immunofluorescence imaging of cancer biopsies, researchers at The Mark Foundation Center for Advanced Genomics and Imaging at Johns Hopkins University and the Bloomberg~Kimmel Institute for Cancer Immunotherapy developed a robust platform to guide immunotherapy by predicting which cancers will respond to specific therapies targeting the immune system. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - June 10, 2021 Category: Cancer & Oncology Source Type: news

Could neutrophils be the secret to cancer's Achilles' heel?
(University of Chicago Medical Center) A study published in the June 10, 2021 issue of Cell describes a remarkable new mechanism by which the body's own immune system can eliminate cancer cells without damaging host cells. The findings have the potential to develop first-in-class medicines that are designed to be selective for cancer cells and non-toxic to normal cells and tissues. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - June 10, 2021 Category: Cancer & Oncology Source Type: news

NCCN cancer experts answer questions about COVID-19 vaccines
(National Comprehensive Cancer Network) National Comprehensive Cancer Network's patient information team provides a patient and caregiver version of recently updated, evidence-based expert consensus recommendations for vaccinating people with cancer against COVID-19. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - June 10, 2021 Category: Cancer & Oncology Source Type: news

Study sheds light on treatment options for devastating childhood brain cancer
(Washington University School of Medicine) Research from Washington University School of Medicine in St. Louis suggests that children with average risk medulloblastoma can receive radiation to a smaller volume of the brain at the end of a six-week course of treatment and still maintain the same disease control as those receiving radiation to a larger area. But the dose of preventive radiation treatments given to the whole brain and spine over the six-week regimen cannot be reduced without reducing survival. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - June 10, 2021 Category: Cancer & Oncology Source Type: news

Screening uptake may contribute to higher risk of colon cancer for black people
(Regenstrief Institute) Black people have a higher risk of colorectal cancer than white people, but this risk is likely not due to genetics. Data from a recent study by researchers from the US Department of Veterans Affairs, Regenstrief Institute and Indiana University School of Medicine adds more data to the existing evidence. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - June 10, 2021 Category: Cancer & Oncology Source Type: news

Could naked mole rats hold key to curing cancer and dementia?
(University of Bradford) Scientists say naked mole rats - a rodent native to West Africa - may hold the key to new treatments for degenerative diseases such as cancer and dementia. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - June 10, 2021 Category: Cancer & Oncology Source Type: news

Ludwig Cancer Research study shows how certain macrophages dampen anti-tumor immunity
(Ludwig Institute for Cancer Research) A Ludwig Cancer Research study adds to growing evidence that immune cells known as macrophages inhabiting the body cavities that house our vital organs can aid tumor growth by distracting the immune system's cancer-killing CD8+ T cells. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - June 10, 2021 Category: Cancer & Oncology Source Type: news

First AI-based tool for predicting genomic subtypes of pancreatic cancer from histology slides
(Owkin, Inc.) AP-HP Greater Paris University Hospitals and Owkin announced the recent results of their ongoing strategic collaboration at ASCO 2021. Their abstract demonstrates the first AI-based tool for predicting genomic subtypes of pancreatic cancer (PDAC) developed from machine learning applied to histology slides. The tool, a trained and validated AI model, is usable in clinical practice worldwide and opens the possibility of patient molecular stratification in routine care and for clinical trials. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - June 10, 2021 Category: Cancer & Oncology Source Type: news

Researchers turned transparent calcite into artificial gold
(Tel-Aviv University) ? Researchers from Tel Aviv University developed a new platform that can serve as a basis for innovative medications.? Applying processes of nanotechnology, the researchers were able to turn transparent calcite into artificial gold that can be used in thermotherapy for various types of cancer. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - June 10, 2021 Category: Cancer & Oncology Source Type: news

Pinpointing how cancer cells turn aggressive
(University of Pennsylvania) As deadly as it is, cancer metastasis is a poorly understood process. A new study led by Penn's Kamen Simeonov and Christopher Lengner describes a cutting-edge tool for tracing the lineage and gene expression of thousands of individual metastatic cancer cells. Their findings open new angles for investigating the processes that drive metastasis. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - June 10, 2021 Category: Cancer & Oncology Source Type: news