Fertility drugs do not increase breast cancer risk, study finds
(King's College London) Drugs routinely used during fertility treatments to release eggs do not increase the risk of developing breast cancer, new research has shown. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - June 21, 2021 Category: Cancer & Oncology Source Type: news
Study suggests blood test could guide precision treatment in bladder cancer
(Queen Mary University of London) A blood test that can detect tiny amounts of circulating cancer DNA may be able to identify risk of cancer recurrence and guide precision treatment in bladder cancer following surgery, according to a clinical study led by Professor Tom Powles from Queen Mary University of London and Barts Health NHS Trust. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - June 21, 2021 Category: Cancer & Oncology Source Type: news
'Suffocating' cancer: A new headway in melanoma immunotherapy
(Luxembourg Institute of Health) Led by Dr. Bassam Janji, from the Luxembourg Institute of Health, the team used gene editing technologies to show how targeting HIF-1α could not only inhibit tumor growth, but also drive cytotoxic immune cells to the cancer tissue. This discovery provided a valuable new target to make resistant melanomas more vulnerable to available anti-cancer treatments. Their findings were recently published in the reputable Oncogene journal. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - June 21, 2021 Category: Cancer & Oncology Source Type: news
Extracellular mRNA transported to the nucleus shows translation-independent function
(Shinshu University) Researchers found a portion of the extracellular messenger RNA (mRNA) are taken up by natural killer cells (NK cells) expressing the mRNA receptor protein and has a function in the cell. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - June 21, 2021 Category: Cancer & Oncology Source Type: news
High-tech in radiology
(Otto-von-Guericke-Universit รค t Magdeburg) In the Magdeburg University Clinic for Radiology, the first patient in Europe has been treated with a new type of liver tumor therapy as a part of a clinical study. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - June 21, 2021 Category: Cancer & Oncology Source Type: news
There's more to genes than DNA: how Mum and Dad add something extra, just for you
(University of Bath) Biologists at the Universities of Bath in the UK and Vienna in Austria have discovered 71 new 'imprinted' genes in the mouse genome, a finding that takes them a step closer to unravelling some of the mysteries of epigenetics - an area of science that describes how genes are switched on (and off) in different cells, at different stages in development and adulthood. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - June 21, 2021 Category: Cancer & Oncology Source Type: news
Running in the blood: Blood lipids are linked to cancer, but depending on family history
(Cactus Communications) Several studies have associated blood lipids with different types of cancer like that of the food pipe or 'esophagus,' but much remains to be understood, to apply this knowledge clinically. A group of Chinese scientists has successfully advanced this line of research, by identifying the role of family history in modifying the association between blood lipids and risk of developing esophageal malignant lesions, according to a new study published in Chinese Medical Journal. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - June 21, 2021 Category: Cancer & Oncology Source Type: news
Carcinogen-exposed cells provide clues in fighting treatment-resistant cancers
This study explores for the first time how the mutation-independent effect of environmental carcinogens leads to the recruitment of CD8+ T cells, the dominant antitumor cell type. Research raises the possibility of an injection of a chemokine known as CCL21 into a tumor to induce an antitumor response through CD8+ T cells. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - June 18, 2021 Category: Cancer & Oncology Source Type: news
Overcoming a newly recognized form of resistance to modern prostate cancer drugs
(Michigan Medicine - University of Michigan) In a new study, a team of researchers uncovered new mechanisms underlying an important type of resistance to modern prostate cancer drugs called lineage plasticity, where castration-resistant prostate cancers undergo a deadly identity switch. They also outline a promising path to overcoming this form of resistance: BET bromodomain inhibitors. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - June 18, 2021 Category: Cancer & Oncology Source Type: news
Antibiotic Novobiocin found to kill tumor cells with DNA-repair glitch
(Dana-Farber Cancer Institute) An antibiotic developed in the 1950s and largely supplanted by newer drugs, effectively targets and kills cancer cells with a common genetic defect, laboratory research by Dana-Farber Cancer Institute scientists shows. The findings have spurred investigators to open a clinical trial of the drug, novobiocin, for patients whose tumors carry the abnormality. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - June 17, 2021 Category: Cancer & Oncology Source Type: news
Red meat consumption may promote DNA damage-assoc. mutation in colorectal cancer patients
(American Association for Cancer Research) Genetic mutations indicative of DNA damage were associated with high red meat consumption and increased cancer-related mortality in patients with colorectal cancer. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - June 17, 2021 Category: Cancer & Oncology Source Type: news
Association of convalescent plasma therapy with survival in patients with blood cancers, COVID-19
(JAMA Network) What The Study Did: Researchers evaluated the association of convalescent plasma treatment with 30-day mortality in hospitalized adults with hematologic (blood) cancers and COVID-19. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - June 17, 2021 Category: Cancer & Oncology Source Type: news
New drug class could treat range of cancers with faulty BRCA genes
(Institute of Cancer Research) - POLQ inhibitors identified as a new class of targeted drugs- New drug class can kill cancer cells with BRCA gene mutations and those that have become resistant to PARP inhibitors- POLQ inhibitor drug soon to be tested in clinical trials (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - June 17, 2021 Category: Cancer & Oncology Source Type: news
Hackensack Meridian CDI scientists develop 'CATCHER' for crucial biomarkers
(Hackensack Meridian Health) A laboratory at the CDI has discovered a highly sensitive methodology that can efficiently find and harness EVs -- particularly exosomes and the micro RNAs they carry. These could be crucial clues to early identification of diseases like cancer (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - June 17, 2021 Category: Cancer & Oncology Source Type: news
Moffitt develops non-invasive approach to predict outcomes in lung cancer
(H. Lee Moffitt Cancer Center& Research Institute) In a new article published in the Journal for ImmunoTherapy of Cancer, Moffitt Cancer Center researchers show that PET/CT images can be used to measure levels of the PD-L1 biomarker of non-small cell lung cancer (NSCLC) patients in a non-invasive manner and, in turn, predict a patient's response to therapy. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - June 17, 2021 Category: Cancer & Oncology Source Type: news
