Joint funded Clinical Scientist Fellowship
Applications are open for the Medical Research Council Clinical Scientist Fellowship (CSF) with a deadline of 4pm, Wednesday 5 April 2017. We are pleased to support these awards as a partner funder.The CSF develops talented medically, and other clinically qualified professionals, who have gained a higher research degree, to lead their own research plans and establish their own research team to make the transition to independent investigator. Applications are invited for the standard CSF, the Tenure Track CSF, or the jointly funded CSF, all of which are considered in open competition.The CSF provides four years' support. Pa...
Source: Arthritis Research UK - March 3, 2017 Category: Rheumatology Source Type: news

Arthritis Research UK welcomes Rodger McMillan as the new Chair of the Board of Trustees
Arthritis Research UK is pleased to announce the appointment of our new Chair, Rodger McMillan. At the same time, we say a fond farewell to Charles Maisey.Rodger, who has been a member of the Board for the past three years, was selected after a rigorous, externally-led selection process. As a scientist, and later as a Senior Vice President of Research and Development at AstraZeneca, Rodger brings his extensive experience in life sciences and healthcare to this role.He spent his distinguished 30-year career in the pharmaceutical industry involved in the discovery and development of new medicines in rheumatology and other in...
Source: Arthritis Research UK - March 2, 2017 Category: Rheumatology Source Type: news

Health services research awards announced
This study is led by Dr Kathryn Martin at the University of Aberdeen. It aims to determine how walk with ease will need to be modified before it could be implemented in the UK, and to gauge the possibility of conducting a trial to evaluate the programme’s effectiveness.Joint funded by Arthritis Research UK, Pfizer and the Chartered Society of Physiotherapy Charitable Trust:Aiming for patient centred treatment through use of the Arthritis Research UK Musculoskeletal Health Questionnaire (MSK-HQ) The Arthritis Research UK Musculoskeletal Health Questionnaire (MSK-HQ) is a short questionnaire that allows people with mus...
Source: Arthritis Research UK - March 1, 2017 Category: Rheumatology Source Type: news

Men 'face unique challenges when coping with rheumatoid arthritis'
Men with rheumatoidarthritis are often struggling to cope with their condition due to unique challenges created by their identities and self-perception, according to a new study. Research carried out by the University of West England and funded by Arthritis Research UK has indicated that men face specific problems when dealing mentally withrheumatoid arthritis that women do not share - and that tailored channels of support may be needed to help them cope. The unique struggles faced by men The study centred on a series of interviews carried out among six focus groups comprising 22 men, who were asked about their experiences...
Source: Arthritis Research UK - February 28, 2017 Category: Rheumatology Source Type: news

MRC Investment in human tissue banking and linked data – discussion session
Message from Dr Stephen Simpson, Director of Research& ProgrammesThe Medical Research Council (MRC) has recently put out a call, titled,‘Capital investment in human tissue banking and linked data, in partnership with charities.’ Through this call, the MRC will support the establishment of a focussed number of world-class human tissue banks and associated linked-data repositories, which will work in close partnership with research charities to enable new avenues of research into disease mechanism, diagnosis and treatment.If you are interested in applying for the above call, we would like to suggest that you ...
Source: Arthritis Research UK - February 27, 2017 Category: Rheumatology Source Type: news

Masonic Charitable Foundation awards grant to microbiome research
The Masonic Charitable Foundation has awarded£90,000 over three years to Arthritis Research UK, to support research into the role of the microbiome in rheumatoid arthritis.The grant will support Dr Frances Williams at King’s College London, to explore whether the mix of bacteria in and on our bodies (known as the microbiome) drives rheumatoid arthritis, or whether changes in these bacteria are a consequence of the disease or the drugs used to treat it.The researchAround 400,000 people in the UK have rheumatoid arthritis but the best drugs available do not work for everyone. We know that the microbiome in people...
Source: Arthritis Research UK - February 27, 2017 Category: Rheumatology Source Type: news

Binding immunoglobulin protein therapy shows promise for rheumatoid arthritis
A promising new approach to treating rheumatoidarthritis using binding immunoglobulin protein (BiP) therapy has shown its potential in a new clinical study. Carried out by King's College London and Guys and St Thomas' NHS Foundation Trust Hospital, the research has indicated that BiP-based treatment could represent a useful intervention for patients who have failed to respond to conventional disease-modifying antirheumaticdrugs (DMARDs). How it works BiP belongs to a class of compounds known as human endoplasmic reticulum-resident stress proteins, and has been shown in preclinical studies to offer anti-inflammatory...
Source: Arthritis Research UK - February 27, 2017 Category: Rheumatology Source Type: news

New early arthritis treatment technique used by UK hospital
A new surgical technique has been utilised by surgeons in Southampton as a means of treating early-stage kneearthritis. The method, known as intramedullary high tibial osteotomy, has been performed by consultant knee and limb reconstruction surgeon Amir Ali Qureshi on three patients at Southampton General Hospital, and could represent a promising new option for those whose conditions have not yet advanced. How the procedure works The technique involves inserting a nail or rod into the tibia and lengthening it externally with a remote-controlled magnet to relieve pressure on the damaged side of the knee, delaying the need f...
Source: Arthritis Research UK - February 22, 2017 Category: Rheumatology Source Type: news

Innovate UK-MoST funding for treatment of early osteoarthritis
An award that we funded as part of our medical technologies proof of concept funding round in 2015 in collaboration with the Innovation Knowledge Centre (University of Leeds), has recently been awarded a£2m Innovate UK-MoST grant, under UK-China Research and Innovation Bridges Competition 2015 scheme. This grant was awarded to continue the development of novel osteochondral scaffold technology for early intervention of osteoarthritis. We would like to congratulate the researchers, led by Dr Chaozong Liu (University College London) on this exciting news and look forward to seeing how the project develops. Os...
Source: Arthritis Research UK - February 15, 2017 Category: Rheumatology Source Type: news

Starter grants for clinical lecturers
Applications are open for the Academy of Medical Sciences starter grants for clinical lecturers scheme with a deadline of 5pm, Wednesday 8 March 2017. Arthritis Research UK is pleased to support these awards as a partner funder.  The grants provide modest‘starter’ funds of up to£30,000 to enable research active Clinical Lecturers to pursue their research work. Clinical Lecturer posts provide a salary but often do not come with the funding to support the costs of the research. This scheme was designed to help bridge this gap by providing Clinical Lecturers with access to modest research funds for up t...
Source: Arthritis Research UK - February 14, 2017 Category: Rheumatology Source Type: news

NSAID therapy 'may offer little actual benefit for back pain'
A study from the George Institute for Global Health in Sydney, Australia has indicated that commonly used non-steroidal anti-inflammatorydrugs (NSAIDs) such as ibuprofen and aspirin have little effect on remedying people's pain, while potentially putting them at risk of debilitating side effects. Doing more harm than good? Published in the Annals of the Rheumatic Diseases, the new study examined data from 35 existing trials, involving more than 6,000 people in total. It aimed to build on previous research showing that paracetamol is ineffective and opioids provide minimal benefit forback pain. Most clinical guidelines ...
Source: Arthritis Research UK - February 6, 2017 Category: Rheumatology Source Type: news

Research programme manager job opportunity
We’re looking for a highly skilled research programme manager to join our clinical studies and experimental medicine team based within the research directorate. Our team of research programme managers are responsible for the effective delivery of our varied research funding schemes and management of the current£100m research investment, which includes reporting research outputs and achievements that are vital to our continued success and growth.As research programme manager, you’ll:keep abreast of developments in clinical research and other assigned areas to help shape our future research funding activiti...
Source: Arthritis Research UK - February 1, 2017 Category: Rheumatology Source Type: news

Priorities in Clinical Research – Call for Applications
Clinical research delivers healthcare science that develops and evaluates the safety, efficacy and effectiveness of medications, devices, diagnostic products and treatment regimens intended for human use. These may be used for prevention, treatment, diagnosis or for relieving symptoms of a disease.Call for applications We are now inviting applications for clinical research funding in the areas highlighted in the current clinical studies group strategies. We aim to fund innovative research that seeks to address key clinical research priorities that will change practice and impact on quality of life, utilising novel tri...
Source: Arthritis Research UK - January 30, 2017 Category: Rheumatology Source Type: news

Eligibility for hip and knee replacement 'could become more restricted'
People with joint conditions in three regions could soon find it more difficult to get access to knee andhip replacement surgery, due to planned changes in eligibility criteria. The choice by three clinical commissioning groups (CCGs) to explore the idea has attracted criticism, as some believe this may suggest that CCGs are looking to change the scoring system used to decide which patients are suitable for these operations. As reported by the Health Service Journal, the Redditch and Bromsgrove, South Worcestershire, and Wyre Forest CCGs - all based in the West Midlands - are planning a reduction in the Oxford hip and knee...
Source: Arthritis Research UK - January 27, 2017 Category: Rheumatology Source Type: news

Immune cell study sheds new light on how inflammatory arthritis begins
This study, published in the medical journal Science Immunology, used multiphoton intravital microscopy - an imaging technology that allows immune cell movements to be tracked in real time - to follow the development of arthritis in lab mice withrheumatoid arthritis, in order to better understand how this works. It was revealed that the presence of immune complexes within the joint space leads to the production of a molecule called C5a, which is then displayed on the inner walls of adjacent blood vessels and causes immune cells called neutrophils to pass into the joint, setting off the process of inflammation. The implicat...
Source: Arthritis Research UK - January 25, 2017 Category: Rheumatology Source Type: news