Regulation of mitochondrial biogenesis in erythropoiesis by mTORC1-mediated protein translation
Nature Cell Biology 19, 626 (2017).
doi:10.1038/ncb3527
Authors: Xin Liu, Yuannyu Zhang, Min Ni, Hui Cao, Robert A. J. Signer, Dan Li, Mushan Li, Zhimin Gu, Zeping Hu, Kathryn E. Dickerson, Samuel E. Weinberg, Navdeep S. Chandel, Ralph J. DeBerardinis, Feng Zhou, Zhen Shao & Jian Xu (Source: Nature Cell Biology)
Source: Nature Cell Biology - May 15, 2017 Category: Cytology Authors: Xin Liu Yuannyu Zhang Min Ni Hui Cao Robert A. J. Signer Dan Li Mushan Li Zhimin Gu Zeping Hu Kathryn E. Dickerson Samuel E. Weinberg Navdeep S. Chandel Ralph J. DeBerardinis Feng Zhou Zhen Shao Jian Xu Tags: Article Source Type: research
The mitochondrial respiratory chain is essential for haematopoietic stem cell function
Nature Cell Biology 19, 614 (2017).
doi:10.1038/ncb3529
Authors: Elena Ansó, Samuel E. Weinberg, Lauren P. Diebold, Benjamin J. Thompson, Sébastien Malinge, Paul T. Schumacker, Xin Liu, Yuannyu Zhang, Zhen Shao, Mya Steadman, Kelly M. Marsh, Jian Xu, John D. Crispino & Navdeep S. Chandel (Source: Nature Cell Biology)
Source: Nature Cell Biology - May 15, 2017 Category: Cytology Authors: Elena Ans ó Samuel E. Weinberg Lauren P. Diebold Benjamin J. Thompson S é bastien Malinge Paul T. Schumacker Xin Liu Yuannyu Zhang Zhen Shao Mya Steadman Kelly M. Marsh Jian Xu John D. Crispino Navdeep S. Chandel Tags: Article Source Type: research
Wounding induces dedifferentiation of epidermal Gata6+ cells and acquisition of stem cell properties
Nature Cell Biology 19, 603 (2017).
doi:10.1038/ncb3532
Authors: Giacomo Donati, Emanuel Rognoni, Toru Hiratsuka, Kifayathullah Liakath-Ali, Esther Hoste, Gozde Kar, Melis Kayikci, Roslin Russell, Kai Kretzschmar, Klaas W. Mulder, Sarah A. Teichmann & Fiona M. Watt (Source: Nature Cell Biology)
Source: Nature Cell Biology - May 15, 2017 Category: Cytology Authors: Giacomo Donati Emanuel Rognoni Toru Hiratsuka Kifayathullah Liakath-Ali Esther Hoste Gozde Kar Melis Kayikci Roslin Russell Kai Kretzschmar Klaas W. Mulder Sarah A. Teichmann Fiona M. Watt Tags: Article Source Type: research
Leptin-receptor-expressing bone marrow stromal cells are myofibroblasts in primary myelofibrosis
Nature Cell Biology 19, 677 (2017).
doi:10.1038/ncb3530
Authors: Matthew Decker, Leticia Martinez-Morentin, Guannan Wang, Yeojin Lee, Qingxue Liu, Juliana Leslie & Lei Ding (Source: Nature Cell Biology)
Source: Nature Cell Biology - May 8, 2017 Category: Cytology Authors: Matthew Decker Leticia Martinez-Morentin Guannan Wang Yeojin Lee Qingxue Liu Juliana Leslie Lei Ding Tags: Article Source Type: research
Regulated IRE1-dependent mRNA decay sets the threshold for dendritic cell survival
Nature Cell Biology 19, 698 (2017).
doi:10.1038/ncb3518
Authors: Simon J. Tavernier, Fabiola Osorio, Lana Vandersarren, Jessica Vetters, Nele Vanlangenakker, Gert Van Isterdael, Karl Vergote, Riet De Rycke, Eef Parthoens, Lianne van de Laar, Takao Iwawaki, Juan R. Del Valle, Chih-Chi Andrew Hu, Bart N. Lambrecht & Sophie Janssens (Source: Nature Cell Biology)
Source: Nature Cell Biology - May 1, 2017 Category: Cytology Authors: Simon J. Tavernier Fabiola Osorio Lana Vandersarren Jessica Vetters Nele Vanlangenakker Gert Van Isterdael Karl Vergote Riet De Rycke Eef Parthoens Lianne van de Laar Takao Iwawaki Juan R. Del Valle Chih-Chi Andrew Hu Bart N. Lambrecht Sophie Janssens Tags: Article Source Type: research
Shh-mediated centrosomal recruitment of PKA promotes symmetric proliferative neuroepithelial cell division
Nature Cell Biology 19, 493 (2017).
doi:10.1038/ncb3512
Authors: Murielle Saade, Elena Gonzalez-Gobartt, Rene Escalona, Susana Usieto & Elisa Martí (Source: Nature Cell Biology)
Source: Nature Cell Biology - April 27, 2017 Category: Cytology Authors: Murielle Saade Elena Gonzalez-Gobartt Rene Escalona Susana Usieto Elisa Mart í Tags: Article Source Type: research
Context-specific roles of EMT programmes in cancer cell dissemination
Nature Cell Biology 19, 416 (2017).
doi:10.1038/ncb3520
Author: M. Angela Nieto
The role of the epithelial-to-mesenchymal transition in tumour progression remains a topic of intense debate. Now, data on the role of Zeb1 in the metastatic spread of pancreatic cancer clarify apparently conflicting views by revealing context-specific, differential use of individual epithelial-to-mesenchymal transition transcription factors in cancer cell dissemination. (Source: Nature Cell Biology)
Source: Nature Cell Biology - April 27, 2017 Category: Cytology Authors: M. Angela Nieto Tags: News and Views Source Type: research
Metabolic changes promote rejection of oncogenic cells
Nature Cell Biology 19, 414 (2017).
doi:10.1038/ncb3521
Authors: Jonathan L. Coloff & Joan S. Brugge
Dysfunctional cells are eliminated from epithelial monolayers by a process known as cell extrusion to maintain tissue homeostasis. Normal epithelial cells are now shown to induce the extrusion of oncogene-transformed cells by inducing metabolic changes in the oncogene-expressing cells through PDK4-mediated inhibition of PDH and mitochondrial metabolism. (Source: Nature Cell Biology)
Source: Nature Cell Biology - April 27, 2017 Category: Cytology Authors: Jonathan L. Coloff Joan S. Brugge Tags: News and Views Source Type: research
SIRT2 and glycolytic enzyme acetylation in pluripotent stem cells
Nature Cell Biology 19, 412 (2017).
doi:10.1038/ncb3522
Authors: Tong Ming Liu & Ng Shyh-Chang
The metabolic transition from mitochondrial oxidative phosphorylation (OXPHOS) to glycolysis is critical for somatic reprogramming of induced pluripotent stem cells (iPSCs). SIRT2 has now been established as a previously unknown regulator of this metabolic transition during somatic reprogramming by controlling the acetylation status of glycolytic enzymes. (Source: Nature Cell Biology)
Source: Nature Cell Biology - April 27, 2017 Category: Cytology Authors: Tong Ming Liu Ng Shyh-Chang Tags: News and Views Source Type: research
Terminating the replication helicase
Nature Cell Biology 19, 410 (2017).
doi:10.1038/ncb3519
Authors: Vincent Gaggioli & Philip Zegerman
A feature of the cell cycle is that the events of one cycle must be reset before the next one begins. A study now shows that the replication machinery is removed from fully replicated DNA by a conserved ubiquitin- and CDC48 (also known as p97)-dependent pathway. This explains how eukaryotic chromosomes are returned to the unreplicated state. (Source: Nature Cell Biology)
Source: Nature Cell Biology - April 27, 2017 Category: Cytology Authors: Vincent Gaggioli Philip Zegerman Tags: News and Views Source Type: research
Science in the age of Trump
Nature Cell Biology 19, 409 (2017).
doi:10.1038/ncb3526
The steep cuts in science funding proposed in the 2018 US budget blueprint have raised alarm in scientific quarters, and signal the current administration's disregard for the significance of science and research in modern society. (Source: Nature Cell Biology)
Source: Nature Cell Biology - April 27, 2017 Category: Cytology Tags: Editorial Source Type: research
Shh-mediated centrosomal recruitment of PKA promotes symmetric proliferative neuroepithelial cell division
Nature Cell Biology 19, 493 (2017).
doi:10.1038/ncb3512
Authors: Murielle Saade, Elena Gonzalez-Gobartt, Rene Escalona, Susana Usieto & Elisa Martí (Source: Nature Cell Biology)
Source: Nature Cell Biology - April 27, 2017 Category: Cytology Authors: Murielle Saade Elena Gonzalez-Gobartt Rene Escalona Susana Usieto Elisa Mart í Tags: Article Source Type: research
Context-specific roles of EMT programmes in cancer cell dissemination
Nature Cell Biology 19, 416 (2017).
doi:10.1038/ncb3520
Author: M. Angela Nieto
The role of the epithelial-to-mesenchymal transition in tumour progression remains a topic of intense debate. Now, data on the role of Zeb1 in the metastatic spread of pancreatic cancer clarify apparently conflicting views by revealing context-specific, differential use of individual epithelial-to-mesenchymal transition transcription factors in cancer cell dissemination. (Source: Nature Cell Biology)
Source: Nature Cell Biology - April 27, 2017 Category: Cytology Authors: M. Angela Nieto Tags: News and Views Source Type: research
Metabolic changes promote rejection of oncogenic cells
Nature Cell Biology 19, 414 (2017).
doi:10.1038/ncb3521
Authors: Jonathan L. Coloff & Joan S. Brugge
Dysfunctional cells are eliminated from epithelial monolayers by a process known as cell extrusion to maintain tissue homeostasis. Normal epithelial cells are now shown to induce the extrusion of oncogene-transformed cells by inducing metabolic changes in the oncogene-expressing cells through PDK4-mediated inhibition of PDH and mitochondrial metabolism. (Source: Nature Cell Biology)
Source: Nature Cell Biology - April 27, 2017 Category: Cytology Authors: Jonathan L. Coloff Joan S. Brugge Tags: News and Views Source Type: research
SIRT2 and glycolytic enzyme acetylation in pluripotent stem cells
Nature Cell Biology 19, 412 (2017).
doi:10.1038/ncb3522
Authors: Tong Ming Liu & Ng Shyh-Chang
The metabolic transition from mitochondrial oxidative phosphorylation (OXPHOS) to glycolysis is critical for somatic reprogramming of induced pluripotent stem cells (iPSCs). SIRT2 has now been established as a previously unknown regulator of this metabolic transition during somatic reprogramming by controlling the acetylation status of glycolytic enzymes. (Source: Nature Cell Biology)
Source: Nature Cell Biology - April 27, 2017 Category: Cytology Authors: Tong Ming Liu Ng Shyh-Chang Tags: News and Views Source Type: research
