Erratum: Tissue-scale coordination of cellular behaviour promotes epidermal wound repair in live mice
Nature Cell Biology 19, 407 (2017).
doi:10.1038/ncb3503
Author: Sangbum Park, David G. Gonzalez, Boris Guirao, Jonathan D. Boucher, Katie Cockburn, Edward D. Marsh, Kailin R. Mesa, Samara Brown, Panteleimon Rompolas, Ann M. Haberman, Yohanns Bellaïche & Valentina Greco (Source: Nature Cell Biology)
Source: Nature Cell Biology - March 31, 2017 Category: Cytology Authors: Sangbum Park David G. Gonzalez Boris Guirao Jonathan D. Boucher Katie Cockburn Edward D. Marsh Kailin R. Mesa Samara Brown Panteleimon Rompolas Ann M. Haberman Yohanns Bella ïche Valentina Greco Tags: Erratum Source Type: research
Hippo interferes with antiviral defences
Nature Cell Biology 19, 267 (2017).
doi:10.1038/ncb3502
Authors: Natalia Muñoz-Wolf & Ed C. Lavelle
The Hippo pathway responds to environmental factors including nutrient availability, cell density and substrate stiffness to regulate organ size. This pathway is now shown to also regulate antiviral defence by modulating the TBK1-mediated control of interferon production. (Source: Nature Cell Biology)
Source: Nature Cell Biology - March 31, 2017 Category: Cytology Authors: Natalia Mu ñoz-Wolf Ed C. Lavelle Tags: News and Views Source Type: research
Talin gets SHANKed in the fight for integrin activation
Nature Cell Biology 19, 265 (2017).
doi:10.1038/ncb3501
Authors: Paul Atherton & Christoph Ballestrem
Genetic mutations in the SHANK family of proteins are linked to multiple neuropsychiatric disorders including autism spectrum disorders. A study now elucidates critical roles for SHANK in regulating integrin-mediated cell–extracellular matrix adhesion, by sequestering integrin activators. (Source: Nature Cell Biology)
Source: Nature Cell Biology - March 31, 2017 Category: Cytology Authors: Paul Atherton Christoph Ballestrem Tags: News and Views Source Type: research
PARL paves the way to apoptosis
Nature Cell Biology 19, 263 (2017).
doi:10.1038/ncb3504
Authors: Naotada Ishihara & Katsuyoshi Mihara
Although the mitochondrial inner membrane rhomboid peptidase PARL is known to participate in critical signalling cascades, its role in apoptosis has remained unclear. PARL is now shown to process the mitochondrial pro-apoptotic protein Smac (also known as DIABLO) for its subsequent release into the cytosol where it antagonizes XIAP-mediated caspase inhibition to promote apoptosis. (Source: Nature Cell Biology)
Source: Nature Cell Biology - March 31, 2017 Category: Cytology Authors: Naotada Ishihara Katsuyoshi Mihara Tags: News and Views Source Type: research
Demystifying blood stem cell fates
Nature Cell Biology 19, 261 (2017).
doi:10.1038/ncb3494
Authors: Fiona K. Hamey & Berthold Göttgens
Determining the differentiation potential of stem and progenitor cells is essential for understanding their function, yet our ability to do so is limited by the restrictions of experimental assays. Based on single-cell functional and molecular profiling experiments, a new computational approach shows how lineage commitment may occur in human haematopoiesis. (Source: Nature Cell Biology)
Source: Nature Cell Biology - March 31, 2017 Category: Cytology Authors: Fiona K. Hamey Berthold G öttgens Tags: News and Views Source Type: research
On data availability, reproducibility and reuse
Nature Cell Biology 19, 259 (2017).
doi:10.1038/ncb3506
Data sharing is an inherent principle of research publication, and information on how data may be accessed is key for the replication and furthering of scientific findings. Here we revisit the policies of Nature Cell Biology on data availability. (Source: Nature Cell Biology)
Source: Nature Cell Biology - March 31, 2017 Category: Cytology Tags: Editorial Source Type: research
Basolateral protrusion and apical contraction cooperatively drive Drosophila germ-band extension
Nature Cell Biology 19, 375 (2017).
doi:10.1038/ncb3497
Authors: Zijun Sun, Christopher Amourda, Murat Shagirov, Yusuke Hara, Timothy E. Saunders & Yusuke Toyama
Throughout development, tissues undergo complex morphological changes, resulting from cellular mechanics that evolve over time and in three-dimensional space. During Drosophila germ-band extension (GBE), cell intercalation is the key mechanism for tissue extension, and the associated apical junction remodelling is driven by polarized myosin-II-dependent contraction. However, the contribution of the basolateral cellular mechanics to GBE remains poo...
Source: Nature Cell Biology - March 27, 2017 Category: Cytology Authors: Zijun Sun Christopher Amourda Murat Shagirov Yusuke Hara Timothy E. Saunders Yusuke Toyama Tags: Letter Source Type: research
Hippo signalling governs cytosolic nucleic acid sensing through YAP/TAZ-mediated TBK1 blockade
Nature Cell Biology 19, 362 (2017).
doi:10.1038/ncb3496
Authors: Qian Zhang, Fansen Meng, Shasha Chen, Steven W. Plouffe, Shiying Wu, Shengduo Liu, Xinran Li, Ruyuan Zhou, Junxian Wang, Bin Zhao, Jianming Liu, Jun Qin, Jian Zou, Xin-Hua Feng, Kun-Liang Guan & Pinglong Xu (Source: Nature Cell Biology)
Source: Nature Cell Biology - March 27, 2017 Category: Cytology Authors: Qian Zhang Fansen Meng Shasha Chen Steven W. Plouffe Shiying Wu Shengduo Liu Xinran Li Ruyuan Zhou Junxian Wang Bin Zhao Jianming Liu Jun Qin Jian Zou Xin-Hua Feng Kun-Liang Guan Pinglong Xu Tags: Article Source Type: research
Endocytic proteins are partitioned at the edge of the clathrin lattice in mammalian cells
Nature Cell Biology 19, 352 (2017).
doi:10.1038/ncb3498
Authors: Kem A. Sochacki, Andrea M. Dickey, Marie-Paule Strub & Justin W. Taraska (Source: Nature Cell Biology)
Source: Nature Cell Biology - March 27, 2017 Category: Cytology Authors: Kem A. Sochacki Andrea M. Dickey Marie-Paule Strub Justin W. Taraska Tags: Article Source Type: research
Altering the threshold of an excitable signal transduction network changes cell migratory modes
Nature Cell Biology 19, 329 (2017).
doi:10.1038/ncb3495
Authors: Yuchuan Miao, Sayak Bhattacharya, Marc Edwards, Huaqing Cai, Takanari Inoue, Pablo A. Iglesias & Peter N. Devreotes (Source: Nature Cell Biology)
Source: Nature Cell Biology - March 27, 2017 Category: Cytology Authors: Yuchuan Miao Sayak Bhattacharya Marc Edwards Huaqing Cai Takanari Inoue Pablo A. Iglesias Peter N. Devreotes Tags: Article Source Type: research
Friction forces position the neural anlage
Nature Cell Biology 19, 306 (2017).
doi:10.1038/ncb3492
Authors: Michael Smutny, Zsuzsa Ákos, Silvia Grigolon, Shayan Shamipour, Verena Ruprecht, Daniel Čapek, Martin Behrndt, Ekaterina Papusheva, Masazumi Tada, Björn Hof, Tamás Vicsek, Guillaume Salbreux & Carl-Philipp Heisenberg (Source: Nature Cell Biology)
Source: Nature Cell Biology - March 27, 2017 Category: Cytology Authors: Michael Smutny Zsuzsa Ákos Silvia Grigolon Shayan Shamipour Verena Ruprecht Daniel Čapek Martin Behrndt Ekaterina Papusheva Masazumi Tada Bj örn Hof Tam ás Vicsek Guillaume Salbreux Carl-Philipp Heisenberg Tags: Article Source Type: research
The TDH –GCN5L1–Fbxo15–KBP axis limits mitochondrial biogenesis in mouse embryonic stem cells
Nature Cell Biology 19, 341 (2017).
doi:10.1038/ncb3491
Authors: Valerio Donato, Massimo Bonora, Daniele Simoneschi, Davide Sartini, Yasusei Kudo, Anita Saraf, Laurence Florens, Michael P. Washburn, Matthias Stadtfeld, Paolo Pinton & Michele Pagano (Source: Nature Cell Biology)
Source: Nature Cell Biology - March 20, 2017 Category: Cytology Authors: Valerio Donato Massimo Bonora Daniele Simoneschi Davide Sartini Yasusei Kudo Anita Saraf Laurence Florens Michael P. Washburn Matthias Stadtfeld Paolo Pinton Michele Pagano Tags: Article Source Type: research
Human haematopoietic stem cell lineage commitment is a continuous process
Nature Cell Biology 19, 271 (2017).
doi:10.1038/ncb3493
Authors: Lars Velten, Simon F. Haas, Simon Raffel, Sandra Blaszkiewicz, Saiful Islam, Bianca P. Hennig, Christoph Hirche, Christoph Lutz, Eike C. Buss, Daniel Nowak, Tobias Boch, Wolf-Karsten Hofmann, Anthony D. Ho, Wolfgang Huber, Andreas Trumpp, Marieke A. G. Essers & Lars M. Steinmetz (Source: Nature Cell Biology)
Source: Nature Cell Biology - March 20, 2017 Category: Cytology Authors: Lars Velten Simon F. Haas Simon Raffel Sandra Blaszkiewicz Saiful Islam Bianca P. Hennig Christoph Hirche Christoph Lutz Eike C. Buss Daniel Nowak Tobias Boch Wolf-Karsten Hofmann Anthony D. Ho Wolfgang Huber Andreas Trumpp Marieke A. G. Essers Lars M. Tags: Article Source Type: research
Endoplasmic-reticulum-mediated microtubule alignment governs cytoplasmic streaming
Nature Cell Biology 19, 399 (2017).
doi:10.1038/ncb3490
Authors: Kenji Kimura, Alexandre Mamane, Tohru Sasaki, Kohta Sato, Jun Takagi, Ritsuya Niwayama, Lars Hufnagel, Yuta Shimamoto, Jean-François Joanny, Seiichi Uchida & Akatsuki Kimura
Cytoplasmic streaming refers to a collective movement of cytoplasm observed in many cell types. The mechanism of meiotic cytoplasmic streaming (MeiCS) in Caenorhabditis elegans zygotes is puzzling as the direction of the flow is not predefined by cell polarity and occasionally reverses. Here, we demonstrate that the endoplasmic reticulum (ER) network structure is required...
Source: Nature Cell Biology - March 13, 2017 Category: Cytology Authors: Kenji Kimura Alexandre Mamane Tohru Sasaki Kohta Sato Jun Takagi Ritsuya Niwayama Lars Hufnagel Yuta Shimamoto Jean-Fran çois Joanny Seiichi Uchida Akatsuki Kimura Tags: Letter Source Type: research
PARL mediates Smac proteolytic maturation in mitochondria to promote apoptosis
Nature Cell Biology 19, 318 (2017).
doi:10.1038/ncb3488
Authors: Shotaro Saita, Hendrik Nolte, Kai Uwe Fiedler, Hamid Kashkar, A. Saskia Venne, René P. Zahedi, Marcus Krüger & Thomas Langer (Source: Nature Cell Biology)
Source: Nature Cell Biology - March 13, 2017 Category: Cytology Authors: Shotaro Saita Hendrik Nolte Kai Uwe Fiedler Hamid Kashkar A. Saskia Venne Ren é P. Zahedi Marcus Kr üger Thomas Langer Tags: Article Source Type: research
