The effect of proteasome inhibitor (AM114) on apoptosis in IL-1 β-treated peripheral blood macrophage cultured cells from rheumatoid arthritis patients
Conclusions The AM114 is efficacious than aspirin-treated IL-1β-treated PBMCC from RA patients by inducing apoptosis and increase in caspase-3 activity. (Source: Indian Journal of Rheumatology)
Source: Indian Journal of Rheumatology - June 17, 2016 Category: Rheumatology Source Type: research
Erratum to “Rheumatology Quiz” [Indian J. Rheumatol. 10 (3) (2015) 147–148]
Publication date: June 2016 Source:Indian Journal of Rheumatology, Volume 11, Issue 2 Author(s): Vivek Arya, Varun Dhir (Source: Indian Journal of Rheumatology)
Source: Indian Journal of Rheumatology - May 27, 2016 Category: Rheumatology Source Type: research
Erratum to “Cost-effective management of rheumatoid arthritis in India” [Indian J. Rheumatol. 8 (4) (2013) 179–182]
Publication date: June 2016 Source:Indian Journal of Rheumatology, Volume 11, Issue 2 Author(s): Vinay R. Joshi, Vivek B. Poojary (Source: Indian Journal of Rheumatology)
Source: Indian Journal of Rheumatology - May 27, 2016 Category: Rheumatology Source Type: research
Methotrexate versus leflunomide: Which one to choose?
Publication date: June 2016 Source:Indian Journal of Rheumatology, Volume 11, Issue 2 Author(s): Gurmeet Singh (Source: Indian Journal of Rheumatology)
Source: Indian Journal of Rheumatology - May 27, 2016 Category: Rheumatology Source Type: research
Development and analysis of validity and reliability of the Kannada version of Oswestry Disability Index
Conclusion ODI-K is reliable and valid tool that can be used in patient oriented outcome studies for evaluating disability related to back pain among Kannada speaking population. (Source: Indian Journal of Rheumatology)
Source: Indian Journal of Rheumatology - April 29, 2016 Category: Rheumatology Source Type: research
Vanishing toe in a patient with rheumatoid arthritis
Publication date: Available online 27 April 2016 Source:Indian Journal of Rheumatology Author(s): Masao Sato (Source: Indian Journal of Rheumatology)
Source: Indian Journal of Rheumatology - April 26, 2016 Category: Rheumatology Source Type: research
Comparative evaluation of efficacy of leflunomide versus combination of methotrexate and hydroxychloroquine in patients of rheumatoid arthritis – An Indian experience
Conclusions LEF was found to have equal efficacy as the combination of MTX and HCQ in reducing DAS28 and CDAI score (i.e. from severe to moderate disease activity) and so may be considered as initial therapy in RA. (Source: Indian Journal of Rheumatology)
Source: Indian Journal of Rheumatology - April 22, 2016 Category: Rheumatology Source Type: research
Telescopic fingers: The severe form of arthritis mutilans
Publication date: Available online 23 April 2016 Source:Indian Journal of Rheumatology Author(s): Marta Oliveira, António Marinho, Vânia Gomes, Márcia Meireles, Fábia Patinha Presented is a case of a 55-year-old woman who was diagnosed with psoriatic arthritis at the age of 48. She is being followed up by the Internal Medicine department since 2008, when she presented with bone resorption of the distal interphalangeal joints, osteolysis at risk of proximal progression, and an active disease that caused substantial functional disability. The patient underwent an orthopedic surgery in 2012, which allowed he...
Source: Indian Journal of Rheumatology - April 22, 2016 Category: Rheumatology Source Type: research
Vaccination in adults with autoimmune inflammatory rheumatic diseases
Publication date: Available online 21 April 2016 Source:Indian Journal of Rheumatology Author(s): Sham Santhanam, Subramanian Swaminathan There is an increased risk of infections in patients with autoimmune inflammatory rheumatic diseases (AIRDs). The risk is more due to immune dysfunction and increased use of immunosuppressive drugs (mainly with the introduction of biologicals). Some of these are vaccine-preventable infections. In this narrative review we have appraised the recent literature on vaccinations in AIRDs along with relevant recommendations available in India. (Source: Indian Journal of Rheumatology)
Source: Indian Journal of Rheumatology - April 21, 2016 Category: Rheumatology Source Type: research
Takayasu's arteritis
Publication date: Available online 16 April 2016 Source:Indian Journal of Rheumatology Author(s): Durga Prasanna Misra, Vir Singh Negi Takayasu's arteritis (TA) is a granulomatous large vessel vasculitis more common in India. We review recently published literature in this field over the past year. Multiple reports based on genetic data and studies in peripheral blood of patients with TA suggest perturbation of the Th17-IL17 axis in these patients, which may be amenable to targeted therapy. Abnormal pro-atherogenic lipid profiles in TA (increased LDL-C and Apo A1, decreased HDL-C and Apo-B) may drive disease proces...
Source: Indian Journal of Rheumatology - April 17, 2016 Category: Rheumatology Source Type: research
Proposed modifications to Beighton criteria for the diagnosis of joint hypermobility in children
Conclusion On the basis of pediatrics physiological and mechanical characteristics, it appears that the Shiari–Javadi criteria are able to detect hypermobile children more accurate. Also, the new criteria appears to be more practical, faster and easier. (Source: Indian Journal of Rheumatology)
Source: Indian Journal of Rheumatology - April 7, 2016 Category: Rheumatology Source Type: research
Childbirth in a woman with antisynthetase syndrome and severe lung disease on long-term rituximab therapy
Publication date: Available online 21 March 2016 Source:Indian Journal of Rheumatology Author(s): Joan Dalmau-Carolà (Source: Indian Journal of Rheumatology)
Source: Indian Journal of Rheumatology - March 21, 2016 Category: Rheumatology Source Type: research
Unusual diffuse, dark blue-black nail dyschromia in a Sri Lankan patient with systemic lupus erythematosus
Publication date: Available online 17 March 2016 Source:Indian Journal of Rheumatology Author(s): Basnayake Mudiyanselage Duminda Bandara Basnayake, Thamara Kannangara (Source: Indian Journal of Rheumatology)
Source: Indian Journal of Rheumatology - March 18, 2016 Category: Rheumatology Source Type: research
A case of severe knee enthesitis on MRI as an initial presentation of enteropathic arthritis
Publication date: Available online 15 March 2016 Source:Indian Journal of Rheumatology Author(s): Qasim Akram, Michael Hughes, Subhasis Basu (Source: Indian Journal of Rheumatology)
Source: Indian Journal of Rheumatology - March 15, 2016 Category: Rheumatology Source Type: research
STAT4 rs7574865 polymorphism in Iranian patients with rheumatoid arthritis
Conclusions Although most studies have proposed STAT4 polymorphisms as a susceptible risk factor for RA, we did not detect any significant association between the STAT4 polymorphism and RA in our study. Population-based studies help to identify genetic determinants of disease susceptibility. Possible explanations for differences in susceptible genetic factors among populations could be different genetic predispositions and contribution of gene–gene or gene–environment interactions. (Source: Indian Journal of Rheumatology)
Source: Indian Journal of Rheumatology - March 15, 2016 Category: Rheumatology Source Type: research
