Corrigendum: Clinical value of serum complement component 1q levels in the prognostic analysis of aneurysmal subarachnoid hemorrhage: a prospective cohort study
(Source: Frontiers in Neurology)
Source: Frontiers in Neurology - March 22, 2024 Category: Neurology Source Type: research

A novel nomogram to predict futile recanalization in patients with acute ischemic stroke undergoing mechanical thrombectomy
ConclusionThe nomogram composed of age, SBP, OTR, and 24 h ICH can effectively predict the probability of FR after MT in AIS patients. (Source: Frontiers in Neurology)
Source: Frontiers in Neurology - March 22, 2024 Category: Neurology Source Type: research

Editorial: Movement disorders in neurometabolic conditions
(Source: Frontiers in Neurology)
Source: Frontiers in Neurology - March 22, 2024 Category: Neurology Source Type: research

Post-COVID postural orthostatic tachycardia syndrome (POTS): a new phenomenon
ConclusionOur sample of post-COVID POTS patients are similar to the diagnosed POTS general population including in comorbidities and autonomic testing. Fatigue was identified by patients as a common and debilitating symptom. We hope that our study will be an early step toward further investigation of post-COVID POTS with focus on the trends identified in this chart review. (Source: Frontiers in Neurology)
Source: Frontiers in Neurology - March 22, 2024 Category: Neurology Source Type: research

Modulations of resting-static functional connectivity on insular by electroacupuncture in subjective tinnitus
DiscussionElectroacupuncture treatment can effectively reduce or eliminate tinnitus symptoms in ST patients and improve the hearing by decreasing FC between the INS and the frontal and temporal brain regions. (Source: Frontiers in Neurology)
Source: Frontiers in Neurology - March 22, 2024 Category: Neurology Source Type: research

Pre-hospital stroke monitoring past, present, and future: a perspective
Integrated brain-machine interface signifies a transformative advancement in neurological monitoring and intervention modalities for events such as stroke, the leading cause of disability. Historically, stroke management relied on clinical evaluation and imaging. While today’s stroke landscape integrates artificial intelligence for proactive clinical decision-making, mainly in imaging and stroke detection, it depends on clinical observation for early detection. Cardiovascular monitoring and detection systems, which have become standard throughout healthcare and wellness settings, provide a model for future cerebrovascula...
Source: Frontiers in Neurology - March 22, 2024 Category: Neurology Source Type: research

TOAST stroke subtype classification in clinical practice: implications for the Get With The Guidelines-Stroke nationwide registry
DiscussionClinical practice TOAST classification subtype diagnoses entered into the GWTG-Stroke registry were accurate in only 61% of patients, a performance rate that, if similarly present at other centers, would hamper the ability of the national registry to provide dependable insights into subtype-related care. Development of an updated ischemic stroke subtype classification system, with algorithmic logic embedded in electronic medical records, is desirable. (Source: Frontiers in Neurology)
Source: Frontiers in Neurology - March 22, 2024 Category: Neurology Source Type: research

Clinical characteristics and MRI features of autoimmune glial fibrillary acidic protein astrocytopathy: a case series of 34 patients
ConclusionGFAP-A presented with meningoencephalomyelitis and meningoencephalitis. The brain lesions were often located in juxtacortical white matter, periventricular white matter, basal ganglia, brainstem, and thalamus. Long segments and transverse were the most frequent spine lesions. Leptomeningeal enhancement was the most frequent enhancement pattern, followed by linear perivascular radial enhancement, which may provide new insight into the differential diagnosis of GFAP-A. (Source: Frontiers in Neurology)
Source: Frontiers in Neurology - March 22, 2024 Category: Neurology Source Type: research

Serum biomarkers in patients with drug-resistant epilepsy: a proteomics-based analysis
ConclusionThe discovery of these differential proteins enriched our understanding of serum biomarkers in patients with DRE and potentially provides guidance for future targeted therapy. (Source: Frontiers in Neurology)
Source: Frontiers in Neurology - March 22, 2024 Category: Neurology Source Type: research

Altered tongue muscle contractile properties coincide with altered swallow function in the adult Ts65Dn mouse model of down syndrome
ConclusionTongue muscle contractile properties are altered in adult Ts65Dn and coincide with altered swallow function. (Source: Frontiers in Neurology)
Source: Frontiers in Neurology - March 22, 2024 Category: Neurology Source Type: research

Clinical experience in intracranial stenting of Wingspan stent system under local anesthesia
ConclusionOur study demonstrates the safety and efficacy of the Wingspan stent system when performed on selected patients under local anesthesia. This approach seems to reduce procedural-related morbidity and be a safe intervention. In addition, it is crucial for surgeons to be aware that patients with perforator-bearing artery stenosis may be at a higher risk of complications. (Source: Frontiers in Neurology)
Source: Frontiers in Neurology - March 22, 2024 Category: Neurology Source Type: research

Early cortico-muscular coherence and cortical network changes in Parkinson ’s patients treated with MRgFUS
DiscussionOne day after MRgFUS thalamotomy, PD patients showed a topographically reordered CMC and decreased cortico-cortical flow, together with a reduced local connection between different nodes. These findings suggest that the reordered cortico-muscular and cortical-networks in the beta band may represent an early physiological readjustment related to MRgFUS Vim lesion. (Source: Frontiers in Neurology)
Source: Frontiers in Neurology - March 22, 2024 Category: Neurology Source Type: research

Multiple sclerosis in a 4-year-old boy: A case report and literature review
We present a 4-year-old boy who initially presented with right-sided hemiparesis and demyelinating lesions on MRI. Follow-up MRI examinations 3 and 6 months later revealed new demyelinating lesions. Ten months after initial presentation, he presented with right-sided hemiparesis, central facial nerve palsy on the right side and new demyelinating lesions on MRI. Two clinical events and new MRI lesions on follow-up MRIs confirmed the diagnosis of POMS. He was treated with rituximab and experienced no further relapses or radiological progression during the follow-up period. (Source: Frontiers in Neurology)
Source: Frontiers in Neurology - March 22, 2024 Category: Neurology Source Type: research

Autosomal recessive primary microcephaly type 2 associated with a novel WDR62 splicing variant that disrupts the expression of the functional transcript
ConclusionThis study enhances our understanding of the genetic heterogeneity associated with MCPH and highlights the pivotal role of genetic testing in the diagnosing and managing of rare neurodevelopmental disorders. Furthermore, it highlights the potential of emerging genetic therapies in treating conditions such as MCPH2. (Source: Frontiers in Neurology)
Source: Frontiers in Neurology - March 21, 2024 Category: Neurology Source Type: research

Association of atopic dermatitis and headache disorder: a systematic review and meta-analyses
ConclusionThe findings of this meta-analysis suggest that atopic dermatitis is a potential risk indicator for headache disorder or migraine. Further studies are still needed to verify our findings due to the substantial heterogeneity in our analyses. (Source: Frontiers in Neurology)
Source: Frontiers in Neurology - March 21, 2024 Category: Neurology Source Type: research