Assessment of fetal corpus callosum biometry by 3D super-resolution reconstructed T2-weighted magnetic resonance imaging
ConclusionSR yields CC biometry akin to US (excluding anterior CC). Thanks to superior 3D visualization and better through plane spatial resolution, SR allows to perform CC biometry more frequently than T2WS. (Source: Frontiers in Neurology)
Source: Frontiers in Neurology - March 26, 2024 Category: Neurology Source Type: research

Case report: Insulinoma masquerades as epilepsy – quantitative EEG analysis
Insulinomas are rare gastrointestinal tumors with an incidence of 1–3 per million inhabitants annually. These tumors result in excessive insulin production, culminating in hypoglycemia. Such hypoglycemia triggers various central nervous system (CNS) manifestations, including headache, confusion, abnormal behavior, and epileptic seizures, which can lead to misdiagnosis as epilepsy. This case report documents a 46-year-old male who presented seizure-like episodes. Episodes occurred mainly during the night, lasting several minutes to hours. Initial seizures were characterized by bizarre behavior and altered responsiveness. ...
Source: Frontiers in Neurology - March 26, 2024 Category: Neurology Source Type: research

Interactions between Schwann cell and extracellular matrix in peripheral nerve regeneration
Peripheral nerve injuries, caused by various reasons, often lead to severe sensory, motor, and autonomic dysfunction or permanent disability, posing a challenging problem in regenerative medicine. Autologous nerve transplantation has been the gold standard in traditional treatments but faces numerous limitations and risk factors, such as donor area denervation, increased surgical complications, and diameter or nerve bundle mismatches. The extracellular matrix (ECM) is a complex molecular network synthesized and released into the extracellular space by cells residing in tissues or organs. Its main components include collage...
Source: Frontiers in Neurology - March 26, 2024 Category: Neurology Source Type: research

The evolution of ventral intermediate nucleus targeting in MRI-guided focused ultrasound thalamotomy for essential tremor: an international multi-center evaluation
ConclusionAcross the study period, FUS centers have evolved their VIM targeting superiorly to target the center of the VIM (2 mm above the ICL) and increased the adoption of tractography to aid VIM localization. This phenomenon is observed across autonomous international centers, suggesting that it is a more optimal site for FUS thalamotomy in tremors. (Source: Frontiers in Neurology)
Source: Frontiers in Neurology - March 26, 2024 Category: Neurology Source Type: research

A systematic review of the clinical evidence for an association between type I hypersensitivity and inner ear disorders
Inner ear disorders have a variety of causes, and many factors can contribute to the exacerbation of cochlear and vestibular pathology. This systematic review aimed to analyze clinical data on the coexistence and potential causal interaction between allergic diseases and inner ear conditions. A search of PubMed and Web of Science identified 724 articles, of which 21 were selected for full-text analysis based on inclusion and exclusion criteria. The epidemiologic evidence found overwhelmingly supports an association between allergic disease and particular inner ear disorders represented by a high prevalence of allergic reac...
Source: Frontiers in Neurology - March 25, 2024 Category: Neurology Source Type: research

Optimal dose of fenfluramine in adjuvant treatment of drug-resistant epilepsy: evidence from randomized controlled trials
ConclusionThe higher range of the licensed dose achieves the optimal balance between efficacy, safety, and tolerability in patients with DS and LGS.Clinical trial registrationhttps://www.crd.york.ac.uk/PROSPERO/, identifier CRD42023392454. (Source: Frontiers in Neurology)
Source: Frontiers in Neurology - March 25, 2024 Category: Neurology Source Type: research

Clinical utility of plasma A β42/40 ratio by LC-MS/MS in Alzheimer’s disease assessment
ConclusionHigh-throughput plasma Aβ42/40 LC-MS/MS assays can help identify patients with low likelihood of AD pathology, which can reduce PET evaluations, allowing for cost savings. (Source: Frontiers in Neurology)
Source: Frontiers in Neurology - March 25, 2024 Category: Neurology Source Type: research

Linguistic changes in neurodegenerative diseases relate to clinical symptoms
ConclusionLinguistic changes such as the use of simpler vocabularies and syntax were detectable in patients with different neurodegenerative diseases and correlated with cognitive decline. Speech has the potential to be a sensitive measure for detecting cognitive impairments across various neurodegenerative diseases. (Source: Frontiers in Neurology)
Source: Frontiers in Neurology - March 25, 2024 Category: Neurology Source Type: research

Elevated troponin levels as a predictor of mortality in patients with acute stroke: a systematic review and meta-analysis
ConclusionElevated troponin levels can serve as a promising predictive marker for both in-hospital and last follow-up mortality in AIS and SAH patients but not in ICH patients. Further prospective studies are needed to validate our findings along with exploring the preventive management of mortality in acute stroke settings. (Source: Frontiers in Neurology)
Source: Frontiers in Neurology - March 25, 2024 Category: Neurology Source Type: research

The ratio of the maximum density values: a new method for predicting hemorrhagic transformation in acute ischemic stroke patients undergoing mechanical thrombectomy
ConclusionThe utilization of RMDV >1 on immediate NCCT scans after MT can predict early HT with good sensitivity and specificity. (Source: Frontiers in Neurology)
Source: Frontiers in Neurology - March 22, 2024 Category: Neurology Source Type: research

Comparative efficacy of acupuncture point stimulation treatments for dialysis patients with uremic pruritus: a systematic review and network meta-analysis
ConclusionOur network meta-analysis provided relative efficacy data for choosing the optimal adjuvant treatment for UP. Combined treatment with acupuncture was more effective than conventional treatment only and was the most promising intervention for treating UP.Systematic review registration: PROSPERO (CRD42023425739: https://www.crd.york.ac.uk/prospero/display_record.php?ID=CRD42023425739). (Source: Frontiers in Neurology)
Source: Frontiers in Neurology - March 22, 2024 Category: Neurology Source Type: research

Editorial: Development of the precision diagnostics and treatment for duchenne/becker muscular dystrophy
(Source: Frontiers in Neurology)
Source: Frontiers in Neurology - March 22, 2024 Category: Neurology Source Type: research

Corrigendum: Clinical value of serum complement component 1q levels in the prognostic analysis of aneurysmal subarachnoid hemorrhage: a prospective cohort study
(Source: Frontiers in Neurology)
Source: Frontiers in Neurology - March 22, 2024 Category: Neurology Source Type: research

A novel nomogram to predict futile recanalization in patients with acute ischemic stroke undergoing mechanical thrombectomy
ConclusionThe nomogram composed of age, SBP, OTR, and 24 h ICH can effectively predict the probability of FR after MT in AIS patients. (Source: Frontiers in Neurology)
Source: Frontiers in Neurology - March 22, 2024 Category: Neurology Source Type: research

Editorial: Movement disorders in neurometabolic conditions
(Source: Frontiers in Neurology)
Source: Frontiers in Neurology - March 22, 2024 Category: Neurology Source Type: research