Sleep disturbances and behavioral symptoms in pediatric Sotos syndrome
ConclusionWe detected an SD in 71.1% of our sample, with a positive relation between SD and internalizing and externalizing symptom levels, especially hyperactivity and impulsivity. Our study demonstrated a high prevalence of SD in pediatric patients with SoS, highlighting that all patients should be screened for this problem, which has a great impact on the quality of life of patients and their families. (Source: Frontiers in Neurology)
Source: Frontiers in Neurology - February 16, 2024 Category: Neurology Source Type: research
Initial experience with radiomics of carotid perivascular adipose tissue in identifying symptomatic plaque
ConclusionThe RS model of PVAT of carotid plaque can be used as an objective indicator to evaluate the risk of plaque and provide a basis for risk stratification of carotid atherosclerotic disease. (Source: Frontiers in Neurology)
Source: Frontiers in Neurology - February 16, 2024 Category: Neurology Source Type: research
The short-term outcome of intracranial stenosis with distal thrombosis treated with balloon-assisted tracking
ConclusionIn conclusion, the use of the balloon-assisted tracking (BAT) technique for treating intracranial stenosis with distal thrombosis (IS&DT) showed promising results. However, a moderate rate of perioperative complications was observed, warranting further investigation and refinement of the procedure. (Source: Frontiers in Neurology)
Source: Frontiers in Neurology - February 16, 2024 Category: Neurology Source Type: research
Effectiveness and safety of auricular acupuncture on adjuvant analgesia in patients with total knee arthroplasty: a randomized sham-controlled trial
ConclusionIn this study, AA was shown to be an effective and safe complementary and alternative therapy for pain relief after TKA, which was able to reduce the total postoperative dose of additional painkillers, decrease serum CRP 1 day after surgery, and improve the degree of postoperative nausea.Clinical trial registrationwww.chictr.org.cn, ChiCTR2100054403. (Source: Frontiers in Neurology)
Source: Frontiers in Neurology - February 16, 2024 Category: Neurology Source Type: research
The relationship between migraine and Hashimoto ’s thyroiditis: a single center experience
ConclusionHT is very prevalent in migraine patients. This is the first study considering migraine and HT to be comorbid and suggesting that HT may influence the course of migraine causing its chronification. (Source: Frontiers in Neurology)
Source: Frontiers in Neurology - February 15, 2024 Category: Neurology Source Type: research
Cilostazol-based dual antiplatelet treatment in ischemic stroke or transient ischemic attack patients with asymptomatic carotid artery disease: a propensity score matching analysis
ConclusionPatients with asymptomatic carotid artery stenosis who received cilostazol-based dual antiplatelet therapy had a lower risk of composite events but a higher risk of minor extracranial hemorrhage than those who received a single antiplatelet agent. (Source: Frontiers in Neurology)
Source: Frontiers in Neurology - February 15, 2024 Category: Neurology Source Type: research
Novel artificial intelligence-based hypodensity detection tool improves clinician identification of hypodensity on non-contrast computed tomography in stroke patients
DiscussionAI-based automated hypodensity detection has potential to enhance clinician accuracy of detecting hypodensity in acute stroke diagnosis, especially for smaller lesions, and notably for less experienced clinicians. (Source: Frontiers in Neurology)
Source: Frontiers in Neurology - February 15, 2024 Category: Neurology Source Type: research
Optimizing the measurement of sample entropy in resting-state fMRI data
DiscussionWe developed an optimized approach to measuring sample entropy that addresses concerns about motion and that can be applied across datasets through user-identified adaptations that allow the method to be tailored to the dataset at hand. We offer preliminary results regarding reproducibility. We also include recommendations for fMRI data acquisition to optimize sample entropy measurement and considerations for the field. (Source: Frontiers in Neurology)
Source: Frontiers in Neurology - February 15, 2024 Category: Neurology Source Type: research
Case report: Dihydropyridine receptor (CACNA1S) congenital myopathy, a novel phenotype with early onset periodic paralysis
ConclusionThis novel phenotype supports the notion that there are age related differences in the clinical expression of CACNA1S gene mutations. This expands our understanding of mutations located in regions of the CACNA1S outside the highly conserved S4 segment, where most mutations thus far have been identified. (Source: Frontiers in Neurology)
Source: Frontiers in Neurology - February 15, 2024 Category: Neurology Source Type: research
Quantitative double echo steady state T2 mapping of upper extremity peripheral nerves and muscles
This study aims to (i) evaluate the effect of DLR methods on DESS-T2 values, and (ii) to evaluate the feasibility of using DESS-T2 maps to differentiate abnormal from normal nerves and muscles in the upper extremities, with abnormality as determined by electromyography.Methods and resultsAnalysis of images from 25 subjects found that DLR decreased DESS-T2 values in abnormal muscles (DLR = 37.71 ± 9.11 msec, standard reconstruction = 38.56 ± 9.44 msec, p = 0.005) and normal muscles (DLR: 27.18 ± 6.34 msec, standard reconstruction: 27.58 ± 6.34 msec, p < 0.001) consistent with a noise reduction bias. Mean DESS-T2, bot...
Source: Frontiers in Neurology - February 15, 2024 Category: Neurology Source Type: research
Digital neuropsychological measures by defense automated neurocognitive assessment: reference values and clinical correlates
This study aims to establish reference values for digital neuropsychological measures obtained through the smartphone-based cognitive assessment application, Defense Automated Neurocognitive Assessment (DANA), and to identify clinical risk factors associated with these measures.MethodsThe sample included 932 cognitively intact participants from the Framingham Heart Study, who completed at least one DANA task. Participants were stratified into subgroups based on sex and three age groups. Reference values were established for digital cognitive assessments within each age group, divided by sex, at the 2.5th, 25th, 50th, 75th,...
Source: Frontiers in Neurology - February 15, 2024 Category: Neurology Source Type: research
Factors associated with older adults ’ cognitive decline 6 months after gamma-variant SARS-CoV-2 infection
ConclusionOur study highlights a profile of cognitive risk aggravation over aging after COVID-19 infection, which is likely mitigated by wealth but worsened in the presence of overweight. Ageusia at the time of acute COVID-19, anxiety, being overweight, and absence of routine intellectual activities are risk factors for more prominent cognitive decline among those infected by COVID-19. (Source: Frontiers in Neurology)
Source: Frontiers in Neurology - February 15, 2024 Category: Neurology Source Type: research
Variability of large timescale functional networks in patients with disorders of consciousness
ConclusionThe functional networks of VS/UWS patients present the most invariant segregation and integration but divergent centrality on the large time scale networks than MCS and EMCS.SignificanceThe variations observed within large timescale functional networks significantly correlate with the degree of consciousness impairment. This finding augments our understanding of the neurophysiological mechanisms underpinning disorders of consciousness. (Source: Frontiers in Neurology)
Source: Frontiers in Neurology - February 15, 2024 Category: Neurology Source Type: research
Emerging biomarkers for improving pregnancy planning in multiple sclerosis
ConclusionWe found no significant differences in AMH, sNfL or GFAP values between MS patients and the control group within any of the age-matched categories. The assessment of AMH, sNFL and GFAP levels at MS onset facilitates personalized therapeutic and family planning strategies for childbearing-age women. (Source: Frontiers in Neurology)
Source: Frontiers in Neurology - February 15, 2024 Category: Neurology Source Type: research
Liquid chromatography coupled to mass spectrometry metabolomic analysis of cerebrospinal fluid revealed the metabolic characteristics of moyamoya disease
ConclusionUtilizing an LC-MS-based metabolomics approach holds promise for enhancing the clinical diagnosis of MMD. The identified biomarkers offer potential avenues for the development of novel diagnostic methods for MMD and offer fresh insights into the pathogenesis of the disease. (Source: Frontiers in Neurology)
Source: Frontiers in Neurology - February 15, 2024 Category: Neurology Source Type: research
