Associations between the burdens of comorbid sleep problems, central sensitization, and headache-related disability in patients with migraine
Conclusion: The present study showed an association between migraine-related disability and the burden of multiple sleep problems, which was partially mediated by CS. (Source: Frontiers in Neurology)
Source: Frontiers in Neurology - February 26, 2024 Category: Neurology Source Type: research
Focused ultrasound therapy in movement disorders: management roadmap towards optimal pathway organization
MRI-guided focused ultrasound (MRgFUS) lesioning is an innovative, safe and effective treatment which provides an innovative development in the field of minimally invasive stereotactic neurosurgery. Based on the application of focused ultrasound energy under full MR planning and thermal imaging control, unilateral lesioning of the thalamus, subthalamic nucleus, and globus pallidus is indicated for the treatment of movement disorders, including essential tremor, Parkinson's disease, and dystonia.We started to apply this technique in February 2019 for the treatment of patients with movement disorders. The authors developed a...
Source: Frontiers in Neurology - February 26, 2024 Category: Neurology Source Type: research
Predictors of overload in parents of children with neuromuscular diseases
This study presents a model that reveals the influence of unemployment, having a child with a severe level of dependency, the presence of somatic symptomatology and life satisfaction on caregiver overload. Likewise, the caregiver's self-esteem could be a protective factor against overload. (Source: Frontiers in Neurology)
Source: Frontiers in Neurology - February 23, 2024 Category: Neurology Source Type: research
Low-contrast visual acuity test is associated with central inflammation and predicts disability development in newly diagnosed multiple sclerosis patients
The visual system is a prominent site of damage in MS since the earliest phases of the disease. Altered low-contrast visual acuity (LCVA) test has been associated with visual impairment and retinal degeneration, predicting medium-and long-term disability. However, it is unclear whether LCVA may also represent a reliable measure of neuroinflammation and a predictor of disease evolution in the very early stages of MS. We explored in a group of 76 consecutive newly diagnosed relapsingremitting MS (RR-MS) patients without visual impairment or altered visual evoked potentials, the association between LCVA scores at 2.5% and 1.2...
Source: Frontiers in Neurology - February 23, 2024 Category: Neurology Source Type: research
Combined cortical thickness and blink reflex recovery cycle to differentiate essential tremor with and without resting tremor
Conclusions: This study highlights the usefulness of adding a simple electrophysiological assessment such as BRrc to MRI cortical morphometric features for accurately distinguishing rET from ET patients, paving the way for a better classification of these ET syndromes. (Source: Frontiers in Neurology)
Source: Frontiers in Neurology - February 23, 2024 Category: Neurology Source Type: research
Bridging the gap: improving correspondence between low-field and high-field magnetic resonance images in young people. Original Research article
Conclusions. Applying super-resolution approaches to low-field imaging improves regional brain volume and surface area accuracy in young people. Finer-scale brain measurements, such as cortical thickness, remain challenging with the limited resolution of low-field systems. (Source: Frontiers in Neurology)
Source: Frontiers in Neurology - February 23, 2024 Category: Neurology Source Type: research
Higher fibrinogen and neutrophil-to-lymphocyte ratio are associated with the early poor response to intravenous thrombolysis in acute ischemic stroke
ConclusionsOur research indicates that the levels of fibrinogen and NLR at admission can be used as a prognostic factor to predict early poor response to intravenous thrombolysis. (Source: Frontiers in Neurology)
Source: Frontiers in Neurology - February 22, 2024 Category: Neurology Source Type: research
Promoting the process of determining brain death through standardized training
ConclusionThe FFT model is suitable for brain death (BD) determination training in China; however, the authors should pay attention to the professional characteristics of participants, strengthen the knowledge gap training, and strive to narrow the difference in training quality. (Source: Frontiers in Neurology)
Source: Frontiers in Neurology - February 22, 2024 Category: Neurology Source Type: research
Combined repetitive facilitative exercise under continuous neuromuscular electrical stimulation and task-oriented training for hemiplegic upper extremity during convalescent phase after stroke: before-and-after feasibility trial
DiscussionThe task-oriented RFE program was safe, well-tolerated, beneficial, and feasible within 80 min a day of occupational therapy, which means also within the procedural constraints of the Japanese health insurance system during the convalescent phase. Future studies are warranted to examine whether combined RFE and TOT enhances the efficacies of each program alone. (Source: Frontiers in Neurology)
Source: Frontiers in Neurology - February 22, 2024 Category: Neurology Source Type: research
Endovascular treatment of symptomatic severe intracranial atherosclerotic stenosis with a novel intracranial dedicated drug-eluting stent: a more effective treatment approach
Endovascular treatment of severe intracranial atherosclerotic stenosis (ICAS) using coronary drug-eluting stents (DESs) significantly reduces the risk of in-stent restenosis (ISR) and stroke recurrence. However, there are few reports regarding the treatment of ICAS with intracranial dedicated DES. Herein, we present our experience with the feasibility, safety, and medium-term follow-up outcomes of a novel intracranial DES, named NOVA stent, in patients with symptomatic severe ICAS ( 70%).From December 2021 to May 2022, patients with symptomatic severe ICAS who underwent implantation of the NOVA stent in our institution...
Source: Frontiers in Neurology - February 22, 2024 Category: Neurology Source Type: research
Editorial: Job integration/reintegration of people with neuromuscular disorders in the epoch of “industry 4.0”
(Source: Frontiers in Neurology)
Source: Frontiers in Neurology - February 21, 2024 Category: Neurology Source Type: research
Atypical neurological manifestations in anti-IgLON5 disease: a case report
Anti-IgLON5 disease is a recently discovered autoimmune encephalopathy with sleep disorder as a hallmark in the majority of reported cases. Additional neurological manifestations include bulbar dysfunction, gait problems, movement disorders, oculomotor abnormalities, and hyperexcitability of the nervous system. At present, an increasing number of publications have dealt with the course and possible treatment options for anti-IgLON5 disease, and its clinical spectrum has expanded wider and more heterogeneous. Here, we report a case of a 66-year-old female with cognitive impairment accompanied by slow reaction, impaired memo...
Source: Frontiers in Neurology - February 21, 2024 Category: Neurology Source Type: research
Clinical characteristics and lateralization of the horizontal semicircular canal light cupula
ConclusionBesides utilizing the NP to determine the affected side, the fast phase direction of the bow nystagmus or lean nystagmus can also aid in identification. However, a simple comparison of the intensity of DCPN in SRT cannot provide accurate lateralization, especially in patients with supine positioning nystagmus. There is a high incidence of CP on the affected side of the light cupula. (Source: Frontiers in Neurology)
Source: Frontiers in Neurology - February 21, 2024 Category: Neurology Source Type: research
Evaluating the efficacy and acceptability of vagus nerve stimulation for fibromyalgia: a PRISMA-compliant protocol for a systematic review and meta-analysis
ConclusionThe findings of our study are anticipated to ascertain the efficacy and acceptability of VNS as a promising treatment option for fibromyalgia. This will not only fill current research gap but also identify potential areas for future research. The findings will provide essential guidance for evidence-based treatment decisions for fibromyalgia, benefiting both patients and clinicians. (Source: Frontiers in Neurology)
Source: Frontiers in Neurology - February 21, 2024 Category: Neurology Source Type: research
Case report: Resolution of Guillain-Barr é syndrome in a patient with dual primary tumors after treatment with rituximab
We report a rare case of GBS in a 64-year-old male patient with dual primary tumors of the colon and stomach who received toripalimab and chemotherapy for liver metastases. After five treatments, the patient experienced weakness and numbness in his limbs. Lumbar puncture, electromyography, and other tests confirmed the diagnosis of GBS. Intravenous immunoglobulin (IVIG) and methylprednisolone did not improve the patient’s symptoms, but rituximab, which is not a standard regimen for GBS, was effective in eliminating B cells and improving symptoms. Following this, we effectively shifted from a regimen combining immunothera...
Source: Frontiers in Neurology - February 21, 2024 Category: Neurology Source Type: research
