Are convictions more dangerous enemies of truth than lies?
This commentary refers to ‘Cardiac pacing in severe recurrent reflex syncope and tilt-induced asystole’, by M. Brignoleet al., doi:10.1093/eurheartj/ehaa936 and the discussion piece ‘Effectiveness of Closed Loop Stimulation pacing in patients with cardio-inhibitory vasovagal reflex syncope is questionable’, by W. Wieling and D.L. Jardine, doi:10.1093/eurheartj/ehab157. (Source: European Heart Journal)
Source: European Heart Journal - March 18, 2021 Category: Cardiology Source Type: research
The management of secondary mitral regurgitation in patients with heart failure: a joint position statement from the Heart Failure Association (HFA), European Association of Cardiovascular Imaging (EACVI), European Heart Rhythm Association (EHRA), and European Association of Percutaneous Cardiovascular Interventions (EAPCI) of the ESC
AbstractSecondary (or functional) mitral regurgitation (SMR) occurs frequently in chronic heart failure (HF) with reduced left ventricular (LV) ejection fraction, resulting from LV remodelling that prevents coaptation of the valve leaflets. Secondary mitral regurgitation contributes to progression of the symptoms and signs of HF and confers worse prognosis. The management of HF patients with SMR is complex and requires timely referral to a multidisciplinary Heart Team. Optimization of pharmacological and device therapy according to guideline recommendations is crucial. Further management requires careful clinical and imagi...
Source: European Heart Journal - March 18, 2021 Category: Cardiology Source Type: research
Past and future of channelopathies and a focus on cardiac arrest
(Source: European Heart Journal)
Source: European Heart Journal - March 14, 2021 Category: Cardiology Source Type: research
What we (don ’t) know about myocardial injury after COVID-19
(Source: European Heart Journal)
Source: European Heart Journal - March 13, 2021 Category: Cardiology Source Type: research
The Birth of Cardiology: The Golden Decade
William Harvey ’s1 momentous discovery and description of the circulation in 1628 is appropriately considered to be one of the great scientific achievements of the high Renaissance. It led to a relatively small number of scattered observations of cardiovascular structure, function, and disease over the following two centuries. One important clinical advance during this period was the stethoscope developed by Laennec2 in 1819, which enhanced examination of the heart and lungs. (Source: European Heart Journal)
Source: European Heart Journal - March 10, 2021 Category: Cardiology Source Type: research
The value of sotagliflozin in patients with diabetes and heart failure detracted by an unexpected ending
Comment on ‘Sotagliflozin in patients with diabetes and recent worsening heart failure’ published in theNew England Journal of Medicine, doi:10.1056/NEJMoa2030183.Key Points (Source: European Heart Journal)
Source: European Heart Journal - March 10, 2021 Category: Cardiology Source Type: research
The association between coronary graft patency and clinical status in patients with coronary artery disease
AbstractThe concept of a direct association between coronary graft patency and clinical status is generally accepted. However, the relationship is more complex and variable than usually thought. Key issues are the lack of a common definition of graft occlusion and of a standardized imaging protocol for patients undergoing coronary bypass surgery. Factors like the type of graft, the timing of the occlusion, and the amount of myocardium at risk, as well as baseline patients ’ characteristics, modulate the patency-to-clinical status association. Available evidence suggests that graft occlusion is more often associated with ...
Source: European Heart Journal - March 8, 2021 Category: Cardiology Source Type: research
Silent brain infarction after TAVR: common but of unclear significance
This editorial refers to ‘Silent brain infarcts and early cognitive outcomes after transcatheter aortic valve implantation: a systematic review and meta-analysis’††, by K. Woldendorpet al., on page1004. (Source: European Heart Journal)
Source: European Heart Journal - March 7, 2021 Category: Cardiology Source Type: research
Challenges in interventional cardiology: embolic complications, cancer patients, and duration of antithrombotic therapy
(Source: European Heart Journal)
Source: European Heart Journal - March 7, 2021 Category: Cardiology Source Type: research
Precision Medicine and cardiac channelopathies: when dreams meet reality
AbstractPrecision Medicine (PM) is an innovative approach that, by relying on large populations ’ datasets, patients’ genetics and characteristics, and advanced technologies, aims at improving risk stratification and at identifying patient-specific management through targeted diagnostic and therapeutic strategies. Cardiac channelopathies are being progressively involved in the evolution br ought by PM and some of them are benefiting from these novel approaches, especially the long QT syndrome. Here, we have explored the main layers that should be considered when developing a PM approach for cardiac channelopathies, wit...
Source: European Heart Journal - March 4, 2021 Category: Cardiology Source Type: research
Genome-wide association analysis in dilated cardiomyopathy reveals two new players in systolic heart failure on chromosomes 3p25.1 and 22q11.23
Conclusion This study provides a better understanding of the genetic architecture of DCM and sheds light on novel biological pathways underlying heart failure. (Source: European Heart Journal)
Source: European Heart Journal - March 3, 2021 Category: Cardiology Source Type: research
Ischaemic and bleeding risk in cancer patients undergoing PCI: another brick in the wall
(Source: European Heart Journal)
Source: European Heart Journal - March 3, 2021 Category: Cardiology Source Type: research
Percutaneous coronary intervention in patients with cancer and readmissions within 90 days for acute myocardial infarction and bleeding in the USA
ConclusionsFollowing PCI, patients with cancer have increased risk for readmissions for AMI or bleeding, with the magnitude of risk depending on both cancer type and the presence of metastasis. (Source: European Heart Journal)
Source: European Heart Journal - March 3, 2021 Category: Cardiology Source Type: research
How inflammation heats the heart
(Source: European Heart Journal)
Source: European Heart Journal - March 1, 2021 Category: Cardiology Source Type: research
A randomized trial supports the recommendation to continue treatment with ACEi or ARBs during hospitalization for COVID-19
Comment on “Effect of Discontinuing vs Continuing Angiotensin-Converting Enzyme Inhibitors and Angiotensin II Receptor Blockers on Days Alive and Out of the Hospital in Patients Admitted With COVID-19” published inJAMA (doi:10.1001/jama.2020.25864) (Source: European Heart Journal)
Source: European Heart Journal - February 28, 2021 Category: Cardiology Source Type: research
