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Understanding the impact of non-alcoholic steatohepatitis with metabolic comorbidities on adults: a real-world qualitative study
Conclusion: Our study provides insights into patients' perspectives of NASH symptoms and their impact on their daily lives. These findings may guide patient-physician conversations, supporting patient-centered treatment decisions and disease management.PMID:38363353 | DOI:10.1080/03007995.2024.2319820 (Source: Current Medical Research and Opinion)
Source: Current Medical Research and Opinion - February 16, 2024 Category: Research Authors: Shraddha Shinde Natalie Taylor Chanadda Chinthammit Rozanne Wilson Somali Misra Burgess Jiat-Ling Poon Source Type: research

Role of the brain-sparing effect on retinopathy of prematurity in newborns with fetal growth restriction
CONCLUSIONS: Gestational age at delivery <30 weeks and birth weight <1500g are independent risk factors for ROP in FGR whereas the BSE is not a risk factor.PMID:38362714 | DOI:10.1080/03007995.2024.2320289 (Source: Current Medical Research and Opinion)
Source: Current Medical Research and Opinion - February 16, 2024 Category: Research Authors: Osman Ahmet Polat Mehmet Mete Kirlangic Erdem Sahin Yusuf Madendag Cem Evereklioglu Fatih Horozoglu Cagatay Karaca Source Type: research

Good Publication Practice (GPP) Guidelines for company-sponsored biomedical research from the point of view of the diverse authors involved in its publication
Curr Med Res Opin. 2024 Feb 16:1-10. doi: 10.1080/03007995.2024.2320298. Online ahead of print.NO ABSTRACTPMID:38362764 | DOI:10.1080/03007995.2024.2320298 (Source: Current Medical Research and Opinion)
Source: Current Medical Research and Opinion - February 16, 2024 Category: Research Authors: Leslie Citrome Lisa M DeTora Dikran Toroser Angela Sykes Trevor Lane Eline Hanekamp Laura Dormer Faith DiBiasi Lise Baltzer Source Type: research

Publishing clinical trial results in plain language: a clash of ethical principles?
Curr Med Res Opin. 2024 Feb 14:1-11. doi: 10.1080/03007995.2024.2308729. Online ahead of print.ABSTRACTPlain language resources (PLR) are lay summaries of clinical trial results or plain language summaries of publications, in digital/visual/language formats. They aim to provide accurate information in jargon-free, and easy-to-understand language that can meet the health information needs of the general public, especially patients and caregivers. These are typically developed by the study sponsors or investigators, or by national public health bodies, research hospitals, patient organizations, and non-profit organizations. ...
Source: Current Medical Research and Opinion - February 14, 2024 Category: Research Authors: Avishek Pal Ingrid Klingmann Tenzin Wangmo Bernice Elger Source Type: research

Association between pan- ımmune ınflammatory value and ulcerative colitis
CONCLUSION: Based on the results of our study, we found that SII and PIV levels were significantly increased in ulcerative colitis patients at the time of diagnosis and were associated with disease severity in the endoscopic scores RACHMILEWITZ, UCEIS and DUBLIN scores, but not for MES score.PMID:38343292 | DOI:10.1080/03007995.2024.2316860 (Source: Current Medical Research and Opinion)
Source: Current Medical Research and Opinion - February 12, 2024 Category: Research Authors: Asl ıhan Mete Yıldırım O ğuzhan Yıldırım Source Type: research

Effectiveness and safety of anticoagulants among patients with venous thromboembolism and active cancer who also had prior bleed or prior renal disease
CONCLUSION: The incidence of MB was higher among those with prior bleed or renal disease. Effects of apixaban, warfarin, or LMWH were generally consistent regardless of prior bleed or renal disease status.PMID:38332714 | DOI:10.1080/03007995.2024.2313092 (Source: Current Medical Research and Opinion)
Source: Current Medical Research and Opinion - February 9, 2024 Category: Research Authors: Alexander T Cohen Virginia Noxon Amol D Dhamane Shrushti Shah Dionne M Hines Tamuno Alfred Jos é Chaves Xuemei Luo Source Type: research

Treatment patterns of galcanezumab versus standard of care preventive migraine medications over 24 months: a US retrospective claims study
CONCLUSION: Patients who initiated galcanezumab for migraine prevention had higher treatment adherence and persistence compared with those who initiated SOC medications after 24-month follow-up.PMID:38334320 | DOI:10.1080/03007995.2024.2316864 (Source: Current Medical Research and Opinion)
Source: Current Medical Research and Opinion - February 9, 2024 Category: Research Authors: Oralee J Varnado Michelle Vu Erin Buysman Gilwan Kim Gayle Allenback Margaret Hoyt Helen Trenz Feng Cao Lars Viktrup Source Type: research

Humanistic burden of mucopolysaccharidoses: a systematic literature review
CONCLUSIONS: This systematic literature review revealed the substantial humanistic burden of individuals affected by MPS as well as caregivers. Significant variation in HRQoL scores was observed, however studies indicate that quality of life of MPS patients is influenced primarily by severity of disease (MPS type and phenotype), and then by time of diagnosis, pain, cognitive involvement, mobility, dependence and time of treatment initiation. Further studies are needed to assess the global humanistic burden of MPS, particularly in MPS III, VI, VII, and IX subtypes, in adults, and for a longer follow-up period. Considering t...
Source: Current Medical Research and Opinion - February 8, 2024 Category: Research Authors: Joyce W Li Kevin Yan Chakrapani Balijepalli Eric Druyts Source Type: research

CercaTest Red, a novel urine-based point-of-care test for the detection of preeclampsia
CONCLUSION: This test is easy to use, cost-effective and portable with short turnaround time and no laboratory instrument requirement. In the future, the test may have the potential to become quantitative using spectroscopy (Chinese Clinical Trial Registry No. ChiCTR1800017692).PMID:38321953 | DOI:10.1080/03007995.2024.2314245 (Source: Current Medical Research and Opinion)
Source: Current Medical Research and Opinion - February 7, 2024 Category: Research Authors: Xuemin Liu Jun Xu Chao Liu Xingmin Li Source Type: research

Risk prediction models of mortality after hip fracture surgery in older individuals: a systematic review
CONCLUSION: Subsequent research endeavors should adopt more stringent experimental designs and employ advanced statistical methodologies in the construction of risk prediction models. Moreover, large-scale external validation studies are warranted to rigorously assess the generalizability and clinical utility of existing models, thereby enhancing their relevance as valuable clinical references.PMID:38323327 | DOI:10.1080/03007995.2024.2307346 (Source: Current Medical Research and Opinion)
Source: Current Medical Research and Opinion - February 7, 2024 Category: Research Authors: Ying Sun Yanhui Liu Yaning Zhu Ruzhen Luo Yiwei Luo Shanshan Wang Zihang Feng Source Type: research

Short-term COVID-19 vaccine adverse effects among adults in Ekiti State, Nigeria
CONCLUSION: This study found that self-reported adverse effects of the Oxford/AstraZeneca COVID-19 vaccine were mild and short in duration. This outcome has promising implications for improving COVID-19 vaccine uptake in the immediate environment and Nigeria.PMID:38323854 | DOI:10.1080/03007995.2024.2316217 (Source: Current Medical Research and Opinion)
Source: Current Medical Research and Opinion - February 7, 2024 Category: Research Authors: Bolade Folasade Dele-Ojo Adedapo Adesokan Joseph Olusesan Fadare Paul Oladapo Ajayi Taiwo Hussean Raimi Samuel Ayokunle Dada Ojo Owolabi Dele James Ayodele Ogunmodede Tope Michael Ipinimo Olumuyiwa Elijah Ariyo Brian Godman Source Type: research