The AI Roadmap - charting our future in healthcare communications [Formula: see text]
Curr Med Res Opin. 2023 Oct 4:1-3. doi: 10.1080/03007995.2023.2261737. Online ahead of print.NO ABSTRACTPMID:37791596 | DOI:10.1080/03007995.2023.2261737 (Source: Current Medical Research and Opinion)
Source: Current Medical Research and Opinion - October 4, 2023 Category: Research Authors: Matt Lewis Elizabeth Mercer Source Type: research

Building trust in real world evidence (RWE): moving transparency in RWE towards the randomized controlled trial standard
Curr Med Res Opin. 2023 Oct 3:1-5. doi: 10.1080/03007995.2023.2263353. Online ahead of print.ABSTRACTThe increasing use of RWE in regulatory and reimbursement decision-making indicates the significant progress that has been made in building trust in RWE through greater transparency. This review of the published literature and key online sources was conducted to provide an update on progress towards greater transparency in RWE, based on four key barriers to trust identified in a 2016 paper and applying learnings from transparency initiatives established for RCTs, such as the US FDA Amendments Act (FDAAA) 2007 Final Rule. Mu...
Source: Current Medical Research and Opinion - October 3, 2023 Category: Research Authors: Richard White Source Type: research

Building trust in real world evidence (RWE): moving transparency in RWE towards the randomized controlled trial standard
Curr Med Res Opin. 2023 Oct 3:1-8. doi: 10.1080/03007995.2023.2263353. Online ahead of print.ABSTRACTThe increasing use of RWE in regulatory and reimbursement decision-making indicates the significant progress that has been made in building trust in RWE through greater transparency. This review of the published literature and key online sources was conducted to provide an update on progress towards greater transparency in RWE, based on four key barriers to trust identified in a 2016 paper and applying learnings from transparency initiatives established for RCTs, such as the US FDA Amendments Act (FDAAA) 2007 Final Rule. Mu...
Source: Current Medical Research and Opinion - October 3, 2023 Category: Research Authors: Richard White Source Type: research

Bioethics of somatic gene therapy: what do we know so far?
CONCLUSION: Our study provides a database of existing challenges and arguments of somatic gene therapy and may serve as the basis of normative analysis. By presenting collected arguments, we contribute to the discussion about the ethics and social dimensions of somatic gene therapy.PMID:37772315 | DOI:10.1080/03007995.2023.2257600 (Source: Current Medical Research and Opinion)
Source: Current Medical Research and Opinion - September 29, 2023 Category: Research Authors: Paola Buedo Alahi Bianchini Katarzyna Klas Marcin Waligora Source Type: research

Medication persistence among people with multiple sclerosis in Slovenia treated with dimethyl fumarate
Conclusions The results of our study proved a high persistence rate among our patients. The most frequent discontinuation reason was gastrointestinal adverse effects. Medication persistence requires interventions in younger patients with an unstable disease course.PMID:37772491 | DOI:10.1080/03007995.2023.2265299 (Source: Current Medical Research and Opinion)
Source: Current Medical Research and Opinion - September 29, 2023 Category: Research Authors: Maj Jo žef Igor Locatelli Gregor BreclJakob Mitja Kos Uro š Rot Source Type: research

Bioethics of somatic gene therapy: what do we know so far?
CONCLUSION: Our study provides a database of existing challenges and arguments of somatic gene therapy and may serve as the basis of normative analysis. By presenting collected arguments, we contribute to the discussion about the ethics and social dimensions of somatic gene therapy.PMID:37772315 | DOI:10.1080/03007995.2023.2257600 (Source: Current Medical Research and Opinion)
Source: Current Medical Research and Opinion - September 29, 2023 Category: Research Authors: Paola Buedo Alahi Bianchini Katarzyna Klas Marcin Waligora Source Type: research

Medication persistence among people with multiple sclerosis in Slovenia treated with dimethyl fumarate
Conclusions The results of our study proved a high persistence rate among our patients. The most frequent discontinuation reason was gastrointestinal adverse effects. Medication persistence requires interventions in younger patients with an unstable disease course.PMID:37772491 | DOI:10.1080/03007995.2023.2265299 (Source: Current Medical Research and Opinion)
Source: Current Medical Research and Opinion - September 29, 2023 Category: Research Authors: Maj Jo žef Igor Locatelli Gregor BreclJakob Mitja Kos Uro š Rot Source Type: research

Bioethics of somatic gene therapy: what do we know so far?
CONCLUSION: Our study provides a database of existing challenges and arguments of somatic gene therapy and may serve as the basis of normative analysis. By presenting collected arguments, we contribute to the discussion about the ethics and social dimensions of somatic gene therapy.PMID:37772315 | DOI:10.1080/03007995.2023.2257600 (Source: Current Medical Research and Opinion)
Source: Current Medical Research and Opinion - September 29, 2023 Category: Research Authors: Paola Buedo Alahi Bianchini Katarzyna Klas Marcin Waligora Source Type: research

Medication persistence among people with multiple sclerosis in Slovenia treated with dimethyl fumarate
Conclusions The results of our study proved a high persistence rate among our patients. The most frequent discontinuation reason was gastrointestinal adverse effects. Medication persistence requires interventions in younger patients with an unstable disease course.PMID:37772491 | DOI:10.1080/03007995.2023.2265299 (Source: Current Medical Research and Opinion)
Source: Current Medical Research and Opinion - September 29, 2023 Category: Research Authors: Maj Jo žef Igor Locatelli Gregor BreclJakob Mitja Kos Uro š Rot Source Type: research

Bioethics of somatic gene therapy: what do we know so far?
CONCLUSION: Our study provides a database of existing challenges and arguments of somatic gene therapy and may serve as the basis of normative analysis. By presenting collected arguments, we contribute to the discussion about the ethics and social dimensions of somatic gene therapy.PMID:37772315 | DOI:10.1080/03007995.2023.2257600 (Source: Current Medical Research and Opinion)
Source: Current Medical Research and Opinion - September 29, 2023 Category: Research Authors: Paola Buedo Alahi Bianchini Katarzyna Klas Marcin Waligora Source Type: research

Medication persistence among people with multiple sclerosis in Slovenia treated with dimethyl fumarate
Conclusions The results of our study proved a high persistence rate among our patients. The most frequent discontinuation reason was gastrointestinal adverse effects. Medication persistence requires interventions in younger patients with an unstable disease course.PMID:37772491 | DOI:10.1080/03007995.2023.2265299 (Source: Current Medical Research and Opinion)
Source: Current Medical Research and Opinion - September 29, 2023 Category: Research Authors: Maj Jo žef Igor Locatelli Gregor BreclJakob Mitja Kos Uro š Rot Source Type: research