Cuff Pressure Control: Are the Claims Inflated?*
No abstract available (Source: Critical Care Medicine)
Source: Critical Care Medicine - September 23, 2022 Category: Emergency Medicine Tags: Editorials Source Type: research

Terlipressin: Leading the Water to the Thirsty*
No abstract available (Source: Critical Care Medicine)
Source: Critical Care Medicine - September 23, 2022 Category: Emergency Medicine Tags: Editorials Source Type: research

Prophylactic Postoperative Noninvasive Ventilation in Adults Undergoing Upper Abdominal Surgery: A Systematic Review and Meta-Analysis
CONCLUSIONS: These findings suggest routine provision of either prophylactic NIV or CPAP following upper abdominal surgery may not be effective to reduce PPCs‚ including in those identified at higher risk. (Source: Critical Care Medicine)
Source: Critical Care Medicine - September 23, 2022 Category: Emergency Medicine Tags: Review Article Source Type: research

Trends in Early and Late Mortality in Patients With Severe Acute Pancreatitis Admitted to ICUs: A Nationwide Cohort Study
CONCLUSIONS: Over the 12-year period examined, mortality in patients with SAP admitted to Dutch ICUs did not change, although after 2010 late mortality decreased. Novel therapies should focus on preventing early mortality in SAP. (Source: Critical Care Medicine)
Source: Critical Care Medicine - September 23, 2022 Category: Emergency Medicine Tags: Clinical Investigations Source Type: research

Incidence and Outcomes of Cardiopulmonary Resuscitation in ICUs: Retrospective Cohort Analysis
OBJECTIVES: We aim to describe incidence and outcomes of cardiopulmonary resuscitation (CPR) efforts and their outcomes in ICUs and their changes over time. DESIGN: Retrospective cohort analysis. SETTING: Patient data documented in the Austrian Center for Documentation and Quality Assurance in Intensive Care database. PATIENTS: Adult patients (age ≥ 18 yr) admitted to Austrian ICUs between 2005 and 2019. INTERVENTIONS: None. MEASUREMENTS ANDN MAIN RESULTS: Information on CPR was deduced from the Therapeutic Intervention Scoring System. End points were overall occurrence rate of CPR ...
Source: Critical Care Medicine - September 23, 2022 Category: Emergency Medicine Tags: Clinical Investigations Source Type: research

Accuracy of the Initial Rhythm to Predict a Short No-Flow Time in Out-of-Hospital Cardiac Arrest
CONCLUSIONS: Our analysis demonstrated that the presence of a shockable rhythm at the time of initial assessment was poorly sensitive and only moderately specific for OHCA patients with a short NFT. The initial rhythm, therefore, should not be used as a surrogate for NFT in clinical decision-making. (Source: Critical Care Medicine)
Source: Critical Care Medicine - September 23, 2022 Category: Emergency Medicine Tags: Clinical Investigations Source Type: research

Right-to-Left Shunts Occur During Cardiopulmonary Resuscitation: Echocardiographic Observations
CONCLUSIONS: Right-to-left shunts can be appreciated during CPR in patients who experience OHCA. Further studies are needed to verify its clinical significance. (Source: Critical Care Medicine)
Source: Critical Care Medicine - September 23, 2022 Category: Emergency Medicine Tags: Clinical Investigations Source Type: research

Clinical Benefits of Early Concurrent Use of Cryoprecipitate and Plasma Compared With Plasma Only in Bleeding Trauma Patients
CONCLUSIONS: Cryo use combined with FFP was significantly associated with reduced mortality in bleeding trauma patients. Future randomized controlled trials are warranted to confirm these results. (Source: Critical Care Medicine)
Source: Critical Care Medicine - September 23, 2022 Category: Emergency Medicine Tags: Clinical Investigations Source Type: research

Interfacility Transport of Critically Ill Patients
CONCLUSIONS: Since 2004, there have been numerous advances in critical care interfacility transport. Clinical deterioration may be mitigated by appropriate patient selection, pretransport optimization, and transport by a well-resourced team and vehicle. There remains a dearth of high-quality controlled studies, but notable advances in monitoring, en route management, transport modality (air vs ground), as well as team composition and training serve as foundations for future inquiry. Guidance from professional organizations remains uncoupled from enforceable regulations, impeding standardization of transport program qua...
Source: Critical Care Medicine - September 23, 2022 Category: Emergency Medicine Tags: Clinical Investigations Source Type: research

Awareness With Paralysis Among Critically Ill Emergency Department Patients: A Prospective Cohort Study*
The objective was to assess the proportion of ED patients experiencing AWP and investigate modifiable variables associated with its occurrence. DESIGN: An a priori planned secondary analysis of a multicenter, prospective, before-and-after clinical trial. SETTING: The ED of three academic medical centers. PATIENTS: Mechanically ventilated adult patients that received neuromuscular blockers. INTERVENTIONS: None. MEASUREMENTS AND MAIN RESULTS: All data related to sedation and analgesia were collected. AWP was the primary outcome, assessed with the modified Brice questionnaire, and was indepe...
Source: Critical Care Medicine - September 23, 2022 Category: Emergency Medicine Tags: Feature Articles Source Type: research

Prehospital Bundle of Care Based on Antibiotic Therapy and Hemodynamic Optimization Is Associated With a 30-Day Mortality Decrease in Patients With Septic Shock*
CONCLUSIONS: A prehospital bundle of care, based on antibiotic therapy and hemodynamic optimization, is associated with a 30-day mortality decrease among patients suffering from SS cared for by an mICU. (Source: Critical Care Medicine)
Source: Critical Care Medicine - September 23, 2022 Category: Emergency Medicine Tags: Feature Articles Source Type: research

Effectiveness of Continuous Cuff Pressure Control in Preventing Ventilator-Associated Pneumonia: A Systematic Review and Meta-Analysis of Randomized Controlled Trials*
CONCLUSIONS: The use of CCPC was associated with a reduction in VAP incidence; however, this was based on very low certainty of evidence due to concerns related to risk of bias and inconsistency. (Source: Critical Care Medicine)
Source: Critical Care Medicine - September 23, 2022 Category: Emergency Medicine Tags: Feature Articles Source Type: research

The Comparative Effectiveness of Vasoactive Treatments for Hepatorenal Syndrome: A Systematic Review and Network Meta-Analysis*
OBJECTIVE: Hepatorenal syndrome (HRS) is associated with high rates of morbidity and mortality. Evidence examining commonly used drug treatments remains uncertain. We assessed the comparative effectiveness of inpatient treatments for HRS by performing a network meta-analysis of randomized clinical trials (RCTs). DATA SOURCES: We searched MEDLINE, Embase, Cochrane Central Register of Controlled Trials, Medline In-Process & Other Non-Indexed Citations, Scopus, and Web of Science from inception. STUDY SELECTION AND DATA EXTRACTION: Pairs of reviewers independently identified eligible RCTs that enrolled patie...
Source: Critical Care Medicine - September 23, 2022 Category: Emergency Medicine Tags: Feature Articles Source Type: research

The authors reply
No abstract available (Source: Critical Care Medicine)
Source: Critical Care Medicine - August 24, 2022 Category: Emergency Medicine Tags: Online Letters to the Editor Source Type: research

Amplify Care
No abstract available (Source: Critical Care Medicine)
Source: Critical Care Medicine - August 24, 2022 Category: Emergency Medicine Tags: Online Letters to the Editor Source Type: research