Factors Associated With Prolonged Mechanical Ventilation in Nontraumatic Subarachnoid Hemorrhage
No abstract available (Source: Critical Care Medicine)
Source: Critical Care Medicine - July 16, 2022 Category: Emergency Medicine Tags: Online Letters to the Editor Source Type: research

Neurologic Outcomes of Survivors of COVID-19–Associated Acute Respiratory Distress Syndrome Requiring Intubation
CONCLUSIONS: COVID-19–associated acute respiratory distress syndrome requiring intubation led to slight-to-severe functional disability in about 60% of survivors 4 months after ICU discharge. Cognitive impairment, muscle weakness, and psychologic symptoms were frequent. A large multicenter study is warranted to allow identification of modifiable factors for improving long-term outcome. (Source: Critical Care Medicine)
Source: Critical Care Medicine - July 16, 2022 Category: Emergency Medicine Tags: Online Clinical Investigations Source Type: research

Relative Hypoglycemia and Lower Hemoglobin A1c-Adjusted Time in Band Are Strongly Associated With Increased Mortality in Critically Ill Patients
OBJECTIVES: To determine the associations of relative hypoglycemia and hemoglobin A1c-adjusted time in blood glucose (BG) band (HA-TIB) with mortality in critically ill patients. DESIGN: Retrospective cohort investigation. SETTING: University-affiliated adult medical-surgical ICU. PATIENTS: Three thousand six hundred fifty-five patients with at least four BG tests and hemoglobin A1c (HbA1c) level admitted between September 14, 2014, and November 30, 2019. INTERVENTIONS: None. MEASUREMENTS AND MAIN RESULTS: Patients were stratified for HbA1c bands of (Source: Critical Care Medicine)
Source: Critical Care Medicine - July 16, 2022 Category: Emergency Medicine Tags: Online Clinical Investigations Source Type: research

Home-Ward Bound?*
No abstract available (Source: Critical Care Medicine)
Source: Critical Care Medicine - July 16, 2022 Category: Emergency Medicine Tags: Editorials Source Type: research

Is “Set It and Forget It” Bad Medicine for Sedation and Analgesia for Intubated Emergency Department Patients?*
No abstract available (Source: Critical Care Medicine)
Source: Critical Care Medicine - July 16, 2022 Category: Emergency Medicine Tags: Editorials Source Type: research

A Call for a Consensus Approach to the Design, Implementation, and Evaluation of Early Warning Systems*
No abstract available (Source: Critical Care Medicine)
Source: Critical Care Medicine - July 16, 2022 Category: Emergency Medicine Tags: Editorials Source Type: research

Sepsis Awareness Is Good, Please Do Not Let It Be Misunderstood*
No abstract available (Source: Critical Care Medicine)
Source: Critical Care Medicine - July 16, 2022 Category: Emergency Medicine Tags: Editorials Source Type: research

Does Interrupting Self-Induced Lung Injury and Respiratory Drive Expedite Early Spontaneous Breathing in the Setting of Early Severe Diffuse Acute Respiratory Distress Syndrome?
No abstract available (Source: Critical Care Medicine)
Source: Critical Care Medicine - July 16, 2022 Category: Emergency Medicine Tags: Viewpoints Source Type: research

Can We Always Trust the Wisdom of the Body?
No abstract available (Source: Critical Care Medicine)
Source: Critical Care Medicine - July 16, 2022 Category: Emergency Medicine Tags: Viewpoints Source Type: research

Emergency Department ICUs Add Value
No abstract available (Source: Critical Care Medicine)
Source: Critical Care Medicine - July 16, 2022 Category: Emergency Medicine Tags: Viewpoints Source Type: research

Outcomes After Direct Discharge Home From Critical Care Units: A Population-Based Cohort Analysis*
CONCLUSIONS: There was no difference in outcomes for patients DDH compared with ward transfer prior to discharge when two approaches were used to minimize confounding within a large health systemwide observational cohort. We did not evaluate how patients are selected for DDH. Our results suggest that with careful patient selection, this practice might be feasible for routine implementation to ensure efficient and safe use of limited healthcare resources. (Source: Critical Care Medicine)
Source: Critical Care Medicine - July 16, 2022 Category: Emergency Medicine Tags: Clinical Investigations Source Type: research

Acquired von Willebrand Syndrome and Desmopressin Resistance During Venovenous Extracorporeal Membrane Oxygenation in Patients With COVID-19: A Prospective Observational Study
CONCLUSIONS: In patients with COVID-19-associated ARDS, AVWS developed soon after initiation of vvECMO. The vWF:A/vWF:Ag ratio was a suitable screening test for AVWS. As desmopressin was ineffective, bleeding during vvECMO-associated AVWS should preferably be treated with concentrates containing vWF. (Source: Critical Care Medicine)
Source: Critical Care Medicine - July 16, 2022 Category: Emergency Medicine Tags: Clinical Investigations Source Type: research

Platelet Phenotype and Function Changes With Increasing Duration of Extracorporeal Membrane Oxygenation
OBJECTIVES: To investigate platelet pathophysiology associated with pediatric extracorporeal membrane oxygenation (ECMO). DESIGN: Prospective observational study of neonatal and pediatric ECMO patients from September 1, 2016, to December 31, 2019. SETTING: The PICU in a large tertiary referral pediatric ECMO center. PATIENTS: Eighty-seven neonates and children ( (Source: Critical Care Medicine)
Source: Critical Care Medicine - July 16, 2022 Category: Emergency Medicine Tags: Clinical Investigations Source Type: research

The Feasibility of Implementing Targeted SEDation in Mechanically Ventilated Emergency Department Patients: The ED-SED Pilot Trial*
OBJECTIVES: Deep sedation in the emergency department (ED) is common, increases deep sedation in the ICU, and is negatively associated with outcome. Limiting ED deep sedation may, therefore, be a high-yield intervention to improve outcome. However, the feasibility of conducting an adequately powered ED-based clinical sedation trial is unknown. Our objectives were to assess trial feasibility in terms of: 1) recruitment, 2) protocol implementation and practice change, and 3) safety. Patient-centered clinical outcomes were assessed to better plan for a future large-scale clinical trial. DESIGN: Pragmatic, multicent...
Source: Critical Care Medicine - July 16, 2022 Category: Emergency Medicine Tags: Clinical Investigations Source Type: research

Electrical Impedance Tomography in Acute Respiratory Distress Syndrome Management
CONCLUSIONS: Electrical impedance tomography is a potential tool for the individualized management of ARDS throughout its different stages. Clinical trials should aim to determine whether a specific approach can improve clinical outcomes in ARDS management. (Source: Critical Care Medicine)
Source: Critical Care Medicine - July 16, 2022 Category: Emergency Medicine Tags: Feature Articles Source Type: research