Primary antiphospholipid syndrome in a male presents with acute digital ischemia: Dramatic response to glucocorticoid
We present a rare case of primary antiphospholipid syndrome in a 38-year-old male who presented with painful digital ischemia. Early initiation of anticoagulation and addition of glucocorticoid led to a significant improvement in the patient. (Source: Clinical Case Reports)
Source: Clinical Case Reports - April 9, 2024 Category: General Medicine Authors: Tanvir Ahammed,
Mohammad Rasel,
Sourav Saha,
Ashif Istiak,
Sabreena Chowdhury Tags: CASE REPORT Source Type: research
Acquired methemoglobinemia due to nitrobenzene poisoning: An unusual acquaintance
Key Clinical MessageNitrobenzene poisoning is a rare yet life-threatening contention. The ensuing acute methemoglobinemia has a high fatality rate, hence early prompt intervention is required. Methylene blue (intravenous or oral) and ascorbic acid are the cornerstones of management. They must be administered to suspected patients without tardiness.AbstractAn aromatic organic chemical used in paints and the printing industry is nitrobenzene. Its poisoning causes potentially fatal methemoglobinemia. One aspect of its management involves reducing the iron moiety from its ferric to ferrous form by administering intravenous met...
Source: Clinical Case Reports - April 9, 2024 Category: General Medicine Authors: Sunil Bhatta,
Pusp Raj Awasthi Tags: CASE REPORT Source Type: research
Natural excretion of a metallic susceptor originating from an ingested heated tobacco stick
Key Clinical MessageClinicians should not only consider the presence of metallic foreign bodies within the digestive tract but also contemplate the possibility of nicotine poisoning during the diagnostic process.AbstractWhen clinicians encounter cases of accidental ingestion of some types of heated tobacco, they must consider not only nicotine poisoning but also the possibility of a metallic foreign body within the digestive tract during diagnosis. In children, even sharp or relatively large ingested foreign bodies can spontaneously pass below the esophagus. Considering that this 12-mm metal piece is small, natural excreti...
Source: Clinical Case Reports - April 9, 2024 Category: General Medicine Authors: Hirohito Doi,
Toshihiko Kakiuchi,
Masafumi Nishino,
Masato Yoshiura Tags: CASE IMAGE Source Type: research
A rare cause of amenorrhea: Hematocolpos in a post ‐cystocele repair patient
We present the case of a 48-year-old female who presented with amenorrhea and abdominal pain following surgical repair of a cystocele. Investigation revealed secondary hematocolpos due to surgical trauma. Surgical drainage and correction of the uterus were performed, resulting in immediate pain relief. This case underscores the importance of considering hematocolpos in patients with post-surgical amenorrhea, and further research is needed to better understand its causes, risk factors, and optimal management strategies. (Source: Clinical Case Reports)
Source: Clinical Case Reports - April 9, 2024 Category: General Medicine Authors: Tibyan Noorallah Mohammed,
Ammar Elgadi,
Gamal Mohi Eldeen Nuri Tags: CASE REPORT Source Type: research
A case of ulcerative colitis complicated by a simple appendiceal opening
Key Clinical MessageThis case report describes the clinical course of a 64-year-old male with intermittent abdominal pain attributed to recurrent ulcers at the appendiceal orifice. Initial investigations in November 2019 revealed chronic gastritis and ulcers at the appendiceal orifice, prompting consideration of ulcerative colitis (UC). The patient responded well to mesalazine therapy, experiencing relief from symptoms and improved colonoscopy findings in May 2020. Despite discontinuing medication, a recurrence of symptoms in August 2021 led to a repeat colonoscopy showing renewed ulcers. Mesalazine was reinstated, resulti...
Source: Clinical Case Reports - April 9, 2024 Category: General Medicine Authors: Xiao Liu,
Fang Fang,
Qingfeng Luo Tags: CASE REPORT Source Type: research
Hemivertebra with pathogenic microdeletion of chromosome 9
Key Clinical MessageHemivertebra is a rare congenital abnormality of the spinal column. Hemivertebra with other structural and cytogenetic abnormalities are reported. The prognosis is favorable with partial hemivertebra and with a single spinal defect as compared to a defect involving full segments and affecting different levels of the spines. The perinatal outcome is obscured when it is associated with other syndromes or cytogenetic abnormality. It is imperative to do serial thorough anatomical ultrasound scanning and to screen for chromosomal abnormality when hemivertebra is detected during pregnancy. (Source: Clinical Case Reports)
Source: Clinical Case Reports - April 8, 2024 Category: General Medicine Authors: Yeshey Dorjey,
Tashi Gyeltshen Tags: CASE REPORT Source Type: research
Gallbladder volvulus in a 5 –years old Vietnamese female: A case report
Key Clinical MessageGallbladder volvulus (GV) is a medical emergency and a rare cause of acute abdominal pain among the pediatric population. GV is more prominent usually in boys in pediatric patients. If it is not diagnosed and surgically intervened promptly, GV will become a life-threating condition. Fortunately, a safe and effective laparoscopic cholecystectomy is now widely indicated. A 5 years old female patient with abdominal pain and heavy much vomiting was referred to the emergency room in our hospital. She was suspiciously diagnosed with acute inflammation of the gallbladder according to the results of abdomina...
Source: Clinical Case Reports - April 8, 2024 Category: General Medicine Authors: Cao Minh Tiep,
Tran Phan Ninh,
Nguyen Dinh Hung,
Nguyen Thi Tuyet Nga,
Nguyen Manh Toan,
Pham Ngoc Hung,
Dang Van Chuc Tags: CASE REPORT Source Type: research
Anesthetic management of a patient with Sturge –Weber syndrome in sagittal split ramus osteotomy surgery
This report presents airway management using submental intubation in sagittal split ramus osteotomy under general anesthesia and aimed to explore better anesthetic management for avoiding the rupture of angiomas in a pat ient with SWS. (Source: Clinical Case Reports)
Source: Clinical Case Reports - April 8, 2024 Category: General Medicine Authors: Aya Oda,
Mitsuhiro Yoshida,
Serika Imamura,
Tamayo Takahashi,
Kana Oue,
Mitsuru Doi,
Yoshitaka Shimizu,
Shigehiro Ono,
Takayuki Nakagawa,
Koichi Koizumi,
Tomonao Aikawa Tags: CASE REPORT Source Type: research
Fumarate hydratase mutation associated uterine leiomyomas: A case report and literature review
Key Clinical MessageThe patient was found to have multiple uterine myomas at the age of 19, underwent laparoscopic myomectomy at the age of 20, and underwent laparotomic myomectomy again at the age of 23 due to the recurrence of uterine myoma. At the age of 25, the patient reappeared with symptoms and recurrence, and was diagnosed with uterine leiomyomas (ULMs) of FH mutation and high-grade squamous intraepithelial lesion (HSIL/CIN III) with gland involvement, after complete examination. Fumarate hydratase (FH) mutation screening is important when gynecologists encounter patients with early onset and multiple ULMs, it can ...
Source: Clinical Case Reports - April 8, 2024 Category: General Medicine Authors: Junyan Zhu,
Shanji Li,
Zhiguo Zhuang,
Hao Chen,
Chao Chen,
Jie Zhu Tags: CASE REPORT Source Type: research
Compound heterozygous B3GALNT2 mutations in a fetus with encephalocele: A case report
We report that a fetus of a pregnant mother who had two consecutive pregnancies with ultrasound-detected encephalocele carried compound heterozygous variants inB3GALNT2 NM_152490.5:c.[1423C > T (p.Gln475Ter)]; [261-2A > G] of maternal and paternal origins, respectively, as confirmed by exome sequencing followed by Sanger sequencing validation. The present case implies that mutations inB3GALNT2, a well-known dystroglycanopathy causative gene, may result in a phenotype of neural tube defect, providing new insights into the clinical spectrum ofB3GALNT2-related disorders. Our study may contribute to prenatal s...
Source: Clinical Case Reports - April 6, 2024 Category: General Medicine Authors: Dandan Ling,
Wanqin Xie,
Xiao Mao,
Shengzhi Yang,
Haiyan Pang,
Ping Yang,
Ping Shen,
Yabing Tang Tags: CASE REPORT Source Type: research
Streptococcus gordonii ‐associated infective endocarditis: Case series, literature review, and genetic study
We describe three cases of infective endocarditis caused byS. gordonii during a four-week period in 2023, and the use of whole-genome sequencing to determine whether these isolates were genetically related. The available literature was reviewed. (Source: Clinical Case Reports)
Source: Clinical Case Reports - April 5, 2024 Category: General Medicine Authors: Gawahir A. Ali,
Andr és Pérez‐López,
Clement Tsui,
Khalid Shunnar,
Anju Sharma,
Emad B. Ibrahim,
Patrick Tang,
Hussam Alsoub,
Wael Goravey Tags: CASE REPORT Source Type: research
Bullous striae distensae in a nephrotic syndrome patient: First case report from the Middle East of a rare presentation and review of the literature
AbstractStriae distensae is a common cutaneous phenomenon that begins as reddish linear atrophic plaques (striae rubra) that over time progress to silvery-white coloration (stria alba). Striae distensae in rare occasions becomes edematous, ulcerative, emphysematous, or urticated. Bullous striae distensae is a sequela of conditions causing interstitial edema along with systemic glucocorticoids use. To our knowledge, only eight cases of bullous striae distensae have been reported in the literature. Herein, we report a 17-year-old female, known case of nephrotic syndrome, presented to our clinic with abdominal fluid-fill cuta...
Source: Clinical Case Reports - April 5, 2024 Category: General Medicine Authors: Sumayyah I. Alrefaie,
Sarah B. Aljoudi,
Houriah Y. Nukaly,
Waseem K. ALHawasawi,
Jehad O. Hariri Tags: CASE REPORT Source Type: research
Bilateral indirect ovarian inguinal hernia in a young female with type 1 Mayer –Rokitansky–Küster–Hauser syndrome: An extremely rare clinical context
Key Clinical MessageIncidence of bilateral inguinal hernia encompassing bilateral ovaries in adult female is very thin and concomitant association with Mayer –Rokitansky–Küster–Hauser syndrome is out of ordinary. Along with surgical management of hernia, these females need multidisciplinary slant to manage gynecological, social, and emotional issues.AbstractIn mature females, bilateral ovarian inguinal hernias are a rarity. In this situation, ultrasonography is the basic adjunct to confirm the diagnosis. Mayer –Rokitansky–Küster–Hauser syndrome is typically linked to ovarian hernias in grown-up females. The m...
Source: Clinical Case Reports - April 5, 2024 Category: General Medicine Authors: Sunil Bhatta,
Hemant Ojha,
Meraj Alam Ansari,
Anuj Shrestha Tags: CASE REPORT Source Type: research
Durable complete response to PET ‐CT driven stereotactic radiation therapy plus pembrolizumab for pleomorphic Pancoast cancer: Case report and literature review
Key Clinical MessagePET-driven SBRT plus pembrolizumab as first-line therapy against pleomorphic Pancoast cancer appears beneficial, probably due to high equivalent doses of SBRT on photopenic necrotic core and synergic immune system stimulation of immunoradiotherapy. (Source: Clinical Case Reports)
Source: Clinical Case Reports - April 5, 2024 Category: General Medicine Authors: Alessandra Castelluccia,
Angela Sardaro,
Artor Niccoli Asabella,
Antonio Rosario Pisani,
Dino Rubini,
Maurizio Portaluri,
Francesco Tramacere Tags: CASE REPORT Source Type: research
A patient with a rare co ‐occurrence of papillary and follicular thyroid carcinomas
We report on a case of a collision tumor consisting of papillary and follicular thyroid carcinoma treated successfully with surgery and radioiodine ablation. (Source: Clinical Case Reports)
Source: Clinical Case Reports - April 5, 2024 Category: General Medicine Authors: Vijayvardhan Kamalumpundi,
Erin Meyers,
Maisoon Torfah,
Marcelo Lima de Gusm ão Correia Tags: CASE REPORT Source Type: research
