A case of leukemia cutis showing annular erythema during the course of Philadelphia chromosome ‐positive acute B‐lymphoblastic leukemia
We report a case of leukemia cutis showing annular erythema during the course of Philadelphia chromosome-positive acute B-lymphoblastic leukemia. The annular appearance may be developed by immunomodulatory effects of blinatumomab. (Source: Clinical Case Reports)
Source: Clinical Case Reports - February 10, 2024 Category: General Medicine Authors: Hizuru Tomita, Yoshimasa Nobeyama, You Sakayori, Rika Matsumoto, Satomi Chujo, Hikaru Suzuki, Akihiko Asahina Tags: CASE REPORT Source Type: research

Symmetrical peripheral gangrene following testicular torsion surgery: A case report
Key Clinical MessageSymmetrical peripheral gangrene (SPG) is very rare condition associated with symmetrical ischemia and gangrene affecting two or more distal extremities. It is almost always associated with septicemia and has a high mortality rate. The rarity of this condition and lack of prospective trials makes its recognition and management difficult. Care providers should maintain a high index of suspicion for SPG in patients with sepsis who develop cyanosis and ischemia of extremities. Doing early culture and sensitivity studies is key in guiding apropriate antibiotic treatment.AbstractSymmetrical peripheral gangren...
Source: Clinical Case Reports - February 9, 2024 Category: General Medicine Authors: Kamoga Dickson, Kato Ronald Tags: CASE REPORT Source Type: research

Focal central neurological disorder in patients with autoimmune thyroid disease without encephalopathy
Key Clinical MessageThe report underscores the necessity for a comprehensive evaluation in patients with suggestive laboratory findings or AITD history. Prompt diagnosis and appropriate management are imperative in averting long-term complications. (Source: Clinical Case Reports)
Source: Clinical Case Reports - February 9, 2024 Category: General Medicine Authors: Parisa Sharifi, Sepideh Paybast, Abdorreza Naser  Moghadasi Tags: CASE SERIES Source Type: research

Perforation of the terminal ileum caused by brucellosis: A case report
We present a case of a 69-year-old man diagnosed with acute diffuse peritonitis and intestinal perforation due toBrucella infection. Surgical intervention revealed ileocecal perforation with wheel spoke-like necrosis. The patient underwent partial resection, ileum closure, and ileostomy. Positive blood culture andBrucella agglutination confirmed the diagnosis. Targeted tetracycline and aminoglycoside treatment led to recovery. (Source: Clinical Case Reports)
Source: Clinical Case Reports - February 9, 2024 Category: General Medicine Authors: Chun Wang, Xiaoran Yang, Jia Zhou, Xu Liu, Yong Yang, Xuzhao Li Tags: CASE REPORT Source Type: research

Surgical management of complex lumbosacral anomaly with minimally invasive spinal fusion: A clinical image
Key Clinical MessageLumbosacral junction anomalies represent a rather frequent finding in patients with low back pain. Involved healthcare professionals should be familiar with these dysplasias, in order to achieve proper diagnosis and optimize clinical outcomes.AbstractDysplastic alterations in lumbosacral junction represent a frequent finding in patients with low back pain. Lumbosacral transitional vertebra (LSTV), spina bifida occulta (SBO) and isthmic spondylolisthesis (IS) present recognized etiologies of low back pain. Herein, we present a rare case of concurrent presence of LSTV, SBO and IS in a middle-aged male ind...
Source: Clinical Case Reports - February 9, 2024 Category: General Medicine Authors: Stylianos Kapetanakis, Constantinos Chaniotakis, Joanna Bladowska, Nikolaos Gkantsinikoudis Tags: CASE IMAGE Source Type: research

Type V gastric ulcer: An unusual etiology of gastrosplenic fistula associated with upper gastrointestinal bleeding
Key Clinical MessageType V gastric ulcer is an unusual etiology of gastrosplenic fistula (GSF). Prompt diagnosis and early embolization of splenic vessels prior to esophagogastroduodenoscopy and surgical resection is crucial. (Source: Clinical Case Reports)
Source: Clinical Case Reports - February 9, 2024 Category: General Medicine Authors: Muhammad Nadeem Yousaf, Riyasha Dahal, Subeena Phull, Vinayak Aryal, Karun Neupane, Hamza Ertugrul, Ebubekir Daglilar Tags: CASE REPORT Source Type: research

The bending technique of a scoring balloon Aperta NSE leading to successful crossing into stents
AbstractA new scoring balloon Aperta NSE has 3 longitudinal nylon elements mounted on the non-compliant balloon surface. Although a high-pressure balloon is usually used as a post-dilation balloon in an implanted stent, it is difficult to pass into the stents because a balloon gets caught in stents in some cases. Aperta NSE has some grooves at elements; therefore, this balloon is bendable and shaped in an arc. The bent scoring balloon could eliminate interference between the balloon and the stents or lesions. Moreover, the point where the tip of the balloon contacts could change. As a result, it helps to improve crossabili...
Source: Clinical Case Reports - February 9, 2024 Category: General Medicine Authors: Naohiro Funayama, Keigo Kayanuma, Daisuke Sunaga, Makoto Furugen Tags: CASE REPORT Source Type: research

Conus medullaris neuroschistosomiasis mimicking Guillain –Barre syndrome: A case of delayed diagnosis leading to permanent neurological damage
In conclusion, spinal NS should be considered in patients presenting with myeloradicular symptoms in regions endemic for schistosomal infection, as delayed recognition can result in irreversible outcomes. (Source: Clinical Case Reports)
Source: Clinical Case Reports - February 9, 2024 Category: General Medicine Authors: Nabil Aljuma'ai, Saif A. Ghabisha, Faisal Ahmed, Taha Al ‐Mwald, Abdullatif Almohtadi, Mohamed Badheeb Tags: CASE REPORT Source Type: research

Delayed Sheehan's syndrome diagnosed during the evaluation of secondary infertility: A case report
Key Clinical MessageSheehan's syndrome may present with postpartum lactation failure and amenorrhea or with features of isolated hypopituitarism to panhypopituitarism. A high index of suspicion is required in a relevant clinical setting of postpartum hemorrhage. (Source: Clinical Case Reports)
Source: Clinical Case Reports - February 9, 2024 Category: General Medicine Authors: Surbhi Saxena, Vishesh Verma, Samir Samadarshi, Thinley Dorji, Jayaraman Muthukrishnan Tags: CASE REPORT Source Type: research

Vascular Ehlers ‐Danlos syndrome: A null COL3A1 variant found in a patient with loin pain without marked cutaneous features (case report)
Electropherogram produced by Sanger sequencing showing heterozygous COL3A1 variant NM_000090.4:c.712C 〉T p.(Arg238Ter) (indicated by arrow) detected in the proband. Key Clinical MessagePatients with null variants may have milder vascular Ehlers-Danlos syndrome, presenting with seemingly non-specific complaints and subtle cutaneous features that may be missed. A high index of suspicion and early genetic testing (aided by next-generation sequencing) were crucial for prevention of life-threatening complications in the patient and family members. (Source: Clinical Case Reports)
Source: Clinical Case Reports - February 9, 2024 Category: General Medicine Authors: Shreenidhi Ranganatha Subramaniam, Lam Fung Yeung, L. Y. Lois Choy, Jeffrey Sung Shing Kwok Tags: CASE REPORT Source Type: research

Treatment of hypoglycemia due to a rare pathogenic variant in AKT2 with waxy maize heat ‐modified starch
This report suggests waxy maize heat is a viable treatment option.AbstractThe serine –threonine kinase AKT2 is a critical mediator of insulin's anabolic effects, particularly cellular glucose uptake. The gain-of-function c.49G>A, p.(Glu17Lys)AKT2 variant results in hypoketotic hypoglycemia with suppressed insulin and free fatty acid levels due to constitutive activation of the insulin signaling cascade. Although biochemical similarities exist among the eight individuals identified to date, the associated phenotype varies considerably. Treatment of these patients remains challenging, consisting primarily of frequent fe...
Source: Clinical Case Reports - February 9, 2024 Category: General Medicine Authors: Madeline Parker, Daphne Yau Tags: CASE REPORT Source Type: research

A rare case of traumatic head arteriovenous fistula
We report a case of traumatic scalp and dural arteriovenous fistula with significant vascular malformation, which is important for our understanding of this disease. (Source: Clinical Case Reports)
Source: Clinical Case Reports - February 8, 2024 Category: General Medicine Authors: Lifan Shao, Guangxin Cao Tags: CASE IMAGE Source Type: research

Case report: Endovascular treatment of transplant renal artery stenosis in patient with normal color duplex ultrasound of the renal artery
We report a rare case of transplant renal artery stenosis in a mid-aged woman who presented with edema, hypertension, and increased creatinine 2  months after kidney transplant. The patient had normal renal arterial resistive index (RI) and perfusion index (PI), and there was only a modest decrease in perfusion on duplex ultrasound. Following the patient's renal stenting treatment, angiographic resolution was observed. After 14 days of r egulated blood pressure following renal artery stenting, she was discharged from the hospital with her edema resolved. Considering complications in patients with clinical manifestation...
Source: Clinical Case Reports - February 8, 2024 Category: General Medicine Authors: Javad Jalili, Hamid Tayebi Khosroshahi, Mehran Malekshoar, Mahshid Dehghan, Aisan Akhgari, Amirhosein Ghafouri  Asbagh Tags: CASE REPORT Source Type: research

A five ‐day‐old child with lipid hemihypertrophy: A case report
We present the case of a 5-day-old female neonate who presented with a visibly enlarged right thigh, right labia majora, and below the right mandible. This case report highlights the importance of early identification, comprehensive evaluation, and multidisciplinary management in neonates with lipid hemihypertrophy to optimize their long-term outcomes and quality of life. (Source: Clinical Case Reports)
Source: Clinical Case Reports - February 8, 2024 Category: General Medicine Authors: Kayvan Mirnia, Maryam Saeedi, Razieh Sangsari, Kimia Kazemzadeh Tags: CASE REPORT Source Type: research

Diagnostic challenge in a 2 ‐year‐old boy poisoned with carbon monoxide: A case report
Key Clinical MessageCarbon monoxide poisoning diagnosis is sometimes very difficult and should be considered in the differential diagnosis list of children's consciousness disorders even in summer.AbstractCarbon monoxide poisoning is very dangerous, and sometimes, it is difficult to diagnose. Especially, this poisoning may have non-specific manifestations in children and can be confused with other diseases. Here we present a 2-year-old child who suffered a disturbance of consciousness during the summer season. He and his family were travelers who had come to Mashhad from Kerman and were staying in a hotel room, after vario...
Source: Clinical Case Reports - February 8, 2024 Category: General Medicine Authors: Anahita Alizadeh, Nafiseh Pourbadakhshan, Nasrin Moazzen Tags: CASE REPORT Source Type: research