Myocardial infarction with nonobstructive coronaries (MINOCA) following rabies postexposure prophylaxis: A case report
We present a case of a 43-year-old male with MINOCA following Rabies PEP. A 43-year-old male, nonsmoker and nonalcoholic, presented to the ER with complaints of acute onset left sided chest pain following the completion of the third dose of intradermal rabies vaccine, whose clinical features, ECG changes and lab reports were suggestive of acute presentation of inferior wall MI. Coronary angiography was performed, which however revealed normal coronaries with only slow flow being noted in the left anterior descending (LAD) artery. Echocardiography later showed a normal study with no other relevant diagnosis unveiled on furt...
Source: Clinical Case Reports - February 21, 2024 Category: General Medicine Authors: Reechashree Dhungana, Prajjwal Pokharel, Chandra Mani Poudel, Raja Ram Khanal, Smriti Shakya, Ratna Mani Gajurel Tags: CASE REPORT Source Type: research

Delayed amyotrophic lateral sclerosis diagnosis with subtle cardiac manifestations: Was anchoring bias contributory?
We report a case of a 55-year-old female who presented with a chief complaint of palpitations and minimal slurred speech on multiple encounters, subsequently leading to a focused cardiovascular workup. It was not until after several hospital encounters that a thorough functional and neuromuscular exam was performed, which ultimately helped to broaden the differential and lead to the diagnosis of ALS. Unfortunately, due to this delayed diagnosis, the patient's functionality was beyond repair. Given the underlying cognitive biases that are present in all clinicians, we hypothesize this patient's sex, presenting symptom, and ...
Source: Clinical Case Reports - February 21, 2024 Category: General Medicine Authors: Neyha Cherin, Shivani Patel, Michelle Jukic Tags: CASE REPORT Source Type: research

Case report of congenital neutropenia type 4 with glucose ‐6‐phosphatase catalytic subunit 3 (G6PC3) deficiency
Key Clinical MessageCongenital neutropenia syndromes encompass a group of genetic disorders characterized by persistent neutropenia and recurrent infections inherited in an autosomal recessive, dominant, or X-linked manner. These syndromes arise from mutations in various genes, and one of the significant genes involved is glucose-6-phosphatase catalytic subunit 3 (G6PC3), giving rise to a condition known as Dursun syndrome. As per existing knowledge, a total of 92 cases of Dursun syndrome have been reported globally, including eight cases from Saudi Arabia. Our study identified two additional cases exhibiting neutropenia s...
Source: Clinical Case Reports - February 21, 2024 Category: General Medicine Authors: Nabil S. Dhayhi, Mohammed A. Mahnashi, Alanoud I. Mokhasha, Lana F. Ahmed, Ahmed E. Shamakhi, Adeeb A. Ageel, Mohammed A. Tohary, Abdulaziz H. Alhazmi Tags: CASE REPORT Source Type: research

Zona pellucida removal resulted in a successful live birth: Report on a case with recurrent implantation failure due to embryonic bacteria contamination
In this study, we employed laser to eliminate the zona pellucida of a contaminated embryo. This approach helps to rescue embryo with bacterial contamination, and improve embryo-endometrium interaction.AbstractTo present a case report on the removal of a contaminated zona pellucida from an embryo of patient with a history of recurrent implantation failure (RIF), which was followed by a successful live birth. We present the case of a 34-year-old patient with a history of 3  years of infertility who underwent in vitro fertilization. During the culture process, the embryos became contaminated, leading to three failed implan...
Source: Clinical Case Reports - February 21, 2024 Category: General Medicine Authors: Son Truong Dang, Huy Phuong Tran, Tuong Nguyen Ho, Loc Thai Ly, Tuyet Thi ‐Diem Hoang, Trang Nguyen‐Khanh Huynh, Anh Tuan Do, Thuan Duc Nguyen, Phuong Thi Dao Tags: CASE REPORT Source Type: research

Correction to “Identification of a mutation in TNRC18 in a patient with clinical features of Fazio–Londe disease”
(Source: Clinical Case Reports)
Source: Clinical Case Reports - February 21, 2024 Category: General Medicine Tags: CORRIGENDUM Source Type: research

Acute myeloid leukemia with unreported translocation (x; 3) (q24; p13): A case report
Key Clinical MessageNovel and rare chromosomal aberrations in AML are important to understand, particularly if associated with tumorigenesis and how they contribute to prognostic risk. It is important that acute leukemia be treated right away. Herein, novel (x; 3) (q24; p13) is described.AbstractAcute myeloid leukemia (AML) is a cancer of the blood and bone marrow. It is the most common type of acute leukemia in adults. This type of cancer usually gets worse quickly if it is not treated. Here, we report an unusual case of AML with an unreported translocation associated with AML. (Source: Clinical Case Reports)
Source: Clinical Case Reports - February 21, 2024 Category: General Medicine Authors: Nasrin Gholami, Amirreza Khalaji, Maghsood Mehri, Saba Mehrtabar, Elham Habibzade Tags: CASE REPORT Source Type: research

Scrotal nodular scabies
Key Clinical MessageScabies is a highly infectious parasitic skin disease, The most common lesions are solid and 2 –3 mm in diameter (papules). Very few cases will develop into nodular scabies, and microscopy is frequently negative in patients with clinically diagnosed nodular scabies. The accuracy of microscopy depends on the expertise of the operator, particularly in finding burrows and extracting the rele vant material. (Source: Clinical Case Reports)
Source: Clinical Case Reports - February 21, 2024 Category: General Medicine Authors: Bo Sang, Zehu Liu, Xiujiao Xia Tags: CASE IMAGE Source Type: research

Transient blindness due to mild reversible encephalopathy in a 7 ‐year‐old boy
A lesion with restriction in the midspelenium of the corpus callosum on diffuse-weighted imaging. Key Clinical MessageMild encephalopathy with a reversible splenial lesion (MERS) is a rare phenomenon, which shows transient lesion in corpus callosum and causes temporary encephalopathy features. A disturbance of consciousness and abnormal and delirious behavior are the most significant neurological symptoms. A seven-year-old child with a history of fever and cough was admitted to our hospital due to sudden bilateral blindness. His physical examination showed confusion, fever, and delirious behavior. No sign of meningeal irri...
Source: Clinical Case Reports - February 20, 2024 Category: General Medicine Authors: Shima Shekari, Farima Farsi, Farah Ashrafzadeh, Shima Imannezhad, Ahmad Sohrab Niazi, Samane Kamali Tags: CASE REPORT Source Type: research

Penile cavernosal abscess after urethral injury
We present a patient catheterized for prostatic lesions who developed sepsis of urinary origin with a penile cavernosal abscess due to urethral injury caused by catheter ballooning. Urethral injury might lead to a life-threatening penile abscess. (Source: Clinical Case Reports)
Source: Clinical Case Reports - February 20, 2024 Category: General Medicine Authors: Koichiro Yamamoto, Hiroyuki Honda, Kou Hasegawa, Hideharu Hagiya, Fumio Otsuka Tags: CASE IMAGE Source Type: research

Phenotypic homozygous familial hypercholesterolemia successfully treated with proprotein convertase subtilisin/kexin type 9 inhibitors
Clinical impact of pharmacotherapy in phenotypic HoFH with large-scale CNVs deletion in heterozygotes. Key Clinical MessageRecent data reveal phenotypic HoFH patients may be responsive to PCSK9 inhibitors, challenging prior assumptions. Genetic testing advancements now more accurately forecast patient responses to these therapies, improving treatment strategies. (Source: Clinical Case Reports)
Source: Clinical Case Reports - February 20, 2024 Category: General Medicine Authors: Ryosuke Tani, Keiji Matsunaga, Yuta Toda, Tomoko Inoue, Hai Ying Fu, Tetsuo Minamino Tags: CASE REPORT Source Type: research

Daptomycin plus ceftaroline salvage therapy for persistent Staphylococcus epidermidis bacteremia
Key Clinical MessageInitial antibiotics for trueStaphylococcus epidermidis bacteremia include vancomycin or linezolid, but if bacteremia persists, consideration should be made for salvage combination therapy regimes such as daptomycin with ceftaroline. (Source: Clinical Case Reports)
Source: Clinical Case Reports - February 20, 2024 Category: General Medicine Authors: Hayden Zhang, Kylie Tran, Richard Lindley, Ravindra Dotel Tags: CASE REPORT Source Type: research

Marfan syndrome in a Ghanaian male: The diagnostic challenges
In this report, we explore the challenges of early diagnosis in this population. (Source: Clinical Case Reports)
Source: Clinical Case Reports - February 20, 2024 Category: General Medicine Authors: Aba A. Folson, Kwabena Oteng Agyapong, Dzifa Dey, Philip Eghan, Billey Quaye Tags: CASE REPORT Source Type: research

Primary cutaneous nocardiosis in an immunocompetent host
Clinical manifestations of primary cutaneous nocardiosis. Key Clinical MessageNocardiosis is a rare opportunistic infection that is classically observed in immunocompromised patients but can also affect immunocompetent individuals. It tends to involve the lung, central nervous system, and skin and is often misdiagnosed. (Source: Clinical Case Reports)
Source: Clinical Case Reports - February 19, 2024 Category: General Medicine Authors: Shihuan He, Youkun Lin Tags: CASE REPORT Source Type: research

A rare case of giant mediastinal thymolipoma in an 18 ‐year man
Key Clinical MessageThymolipoma is a rare benign thymic lesion that can manifest as a sizable anterior mediastinal mass. Considering their rarity and challenging preoperative diagnosis, it is crucial to consider these tumors when dealing with anterior mediastinal masses. (Source: Clinical Case Reports)
Source: Clinical Case Reports - February 19, 2024 Category: General Medicine Authors: Hourieh Soleimani, Behzad Aminzadeh, Ehsan Hassannejad, Asma Payandeh, Batul Oudi, Neda Karimabadi Tags: CASE REPORT Source Type: research

Atraumatic intra ‐articular, extra‐synovial ganglion cyst of the lateral knee deep to the iliotibial band: A case report and review of the literature
We present the first reported case of an atraumatic intraarticular, extra-synovial ganglion cyst of the lateral knee located deep to the iliotibial band that was successfully treated without operative intervention through repeated intra-articular aspirations of the knee. (Source: Clinical Case Reports)
Source: Clinical Case Reports - February 19, 2024 Category: General Medicine Authors: Alvarho Guzman, Nicholas Williams, Therese Dela  Rueda, Edward Xiao, Arina Caliman, James L. Chen, Patrick J. McGahan Tags: CASE REPORT Source Type: research