Unilateral tongue atrophy as the initial clinical manifestation in a patient with prostate cancer
A. Patient with left tongue atrophy, arrow indicating protrusion. B. Magnetic Resonance Imaging (MRI) of the Brain in Axial Cut, Flair Sequence. In image B, hyperintensity is observed in the left half of the tongue, highlighting marked atrophy (indicated by the arrow). Key Clinical MessageUnilateral tongue atrophy can be a rare and crucial early indicator of metastatic prostate cancer, highlighting the need for vigilant monitoring in clinical assessments. This case underscores the importance of considering cranial nerve involvement, especially the twelfth, for timely intervention and comprehensive patient care.AbstractPros...
Source: Clinical Case Reports - March 8, 2024 Category: General Medicine Authors: Mohammed Zahran, Henry Larios, Victor Rosales, Adrian Coulson Tags: CASE REPORT Source Type: research

Paraneoplastic movement disorder due to suspected metastatic Leiomyosarcoma of tongue: A case report
FDG-avid metastatic pulmonary nodules in a patient with leiomyosarcoma. Key Clinical MessageParaneoplastic movement disorders, though rare, can be the initial symptoms of malignancies like leiomyosarcoma, as in our case. Clinicians should keep malignancies in their differential diagnosis in cases of unexplained movement abnormalities. (Source: Clinical Case Reports)
Source: Clinical Case Reports - March 8, 2024 Category: General Medicine Authors: Pradeep Khanal, Pitambar Khanal, Sandip Paudel, Ashbita Pokhrel, Subodh Chapagain Tags: CASE REPORT Source Type: research

Approach using the bath preparation containing rice extract for severe pruritus in a patient receiving hemodialysis: A case report
Key Clinical MessageSevere pruritus in a hemodialysis patient who had difficulty applying topical medication markedly reduced with the use of bath preparation containing rice extract. The bath preparation could be effective and an option for treating pruritus. (Source: Clinical Case Reports)
Source: Clinical Case Reports - March 8, 2024 Category: General Medicine Authors: Hiroshi Suzuki, Katsuya Yamauchi, Shinya Uchida Tags: CASE REPORT Source Type: research

Kayser –Fleischer rings: The pathognomonic for Wilson's disease
Key Clinical MessageWilson's disease is a genetic disorder of copper metabolism that primarily manifests with hepatic and neurological features. Kayser –Fleischer rings (KF rings) are pathognomonic of Wilson's disease and helps in establishing its diagnosis. (Source: Clinical Case Reports)
Source: Clinical Case Reports - March 8, 2024 Category: General Medicine Authors: Priyanka Singh, Bachaspati Subedi, Devraj Mahato, Mitesh Karn Tags: CASE IMAGE Source Type: research

Acute pancreatitis secondary to moderate hypertriglyceridemia: A case report
We report a case of a 26-year-old para-2, living-2 (P2L2) female who presented with epigastric pain and fever, with a serum tri glyceride level of 579 mg/dL. A diagnosis of acute pancreatitis was made based on the clinical features and radiological findings, despite no identifiable risk factors. Hypertriglyceridemia was managed with no complications of acute pancreatitis during treatment. (Source: Clinical Case Reports)
Source: Clinical Case Reports - March 8, 2024 Category: General Medicine Authors: Anil Nepali, Satyam Kharga, Malavika Jayan, Prakriti Adhikari, Amit Shah, Vivek Sanker Tags: CASE REPORT Source Type: research

Mixed treatment for same ‐severe mixed urinary incontinence: A novel method
This study reports treatment of a MUI case in a 56-year-old, with a history of MUI of 7-year duration, which was persistent to pharmacological treatment, pelvic muscle training, biofeedback, and anti-incontinence surgery (Burch Colposuspension). PRP-Fibrin Glue-Stem Cell injection, Botox injection, and TVT were performed in a one surgery session. Patient was discharged with ability to urinate with acceptable amount of post void residue. After 3-month follow-up, patient was completely satisfied and happy. Further research is needed to substantiate the efficacy of these mixed treatments for MUI. (Source: Clinical Case Reports)
Source: Clinical Case Reports - March 8, 2024 Category: General Medicine Authors: Daryoush Hamidi  Alamdari, Armina Douzandeh, Maliheh Keshvari Shirvan, Behzad Narouie, Negar Radpour Tags: CASE REPORT Source Type: research

Laparoscopic transhiatal en ‐mass thoracic duct ligation for persistent bilateral spontaneous Chylothorax: A case report
We describe a successful laparoscopic transhiatal en-mass TDL in a 61-year-old lady for persistent spontaneous chylothorax after failed optimal conservative management and three sessions of pleurodesis. The study shows that laparoscopic transhiatal thoracic duct ligation is an effective alternative in a case where thoracoscopy is not feasible due to various reasons. (Source: Clinical Case Reports)
Source: Clinical Case Reports - March 7, 2024 Category: General Medicine Authors: Kunal Bikram Deo, Sumit Kumar Deo, Sujan Gautam, Narendra Pandit, Shailesh Adhikary Tags: CASE REPORT Source Type: research

The skin as a window to the gut: A case of carcinoid syndrome
We report the case of a 66-year-old woman presenting with chronic diarrhea, facial venous telangiectasia and elevated urinary 5-hydrocyindoleacetic acid levels. A 68-Ga DOTATOC PET/CT scan revealed an ileal mass and lesions consistent with liver, ovary and bone metastasis. A liver biopsy confirmed the diagnosis of well-differentiated NET G1. Therapy with somatostatin analogs achieved symptom control, but the liver disease progressed and the patient passed away after 2  years of follow-up. The challenge of diagnosing CS resides in its heterogeneous manifestations, which may range from mild to life-threatening conditions. ...
Source: Clinical Case Reports - March 7, 2024 Category: General Medicine Authors: Catarina Alves Costa, T ânia Lopes, Ana Patrícia Rodrigues, Nuno Jorge Lamas, Célia Cruz Tags: CASE REPORT Source Type: research

Cardiac mass as the primary diagnostic clue of Edheim –Chester disease
Key Clinical MessageWe introduced one of the rare causes of intra-cardiac mass, that is, ECD and a new gene mutation (SLC29A3) that is probably related to this disease, and we noted the importance of using several diagnostic methods to rule out other intra-cardiac causes.AbstractEdheim –Chester disease is a rare histiocytosis affecting multiple organs. The infiltration of lipid-laden histiocytes characterizes the disease. Most patients experience bone involvement; over 50% of cases involve the cardiovascular system and other extra-osseous organs. In this case report, we present the case of a 42-year-old man who complaine...
Source: Clinical Case Reports - March 7, 2024 Category: General Medicine Authors: Azin Alizadehasl, Maryam Mohseni Salehi, Zeinab Soltani, Soudeh Roudbari, Mahsa Akbarian, Somaye Mohebbi, Pegah Salehi Tags: CASE REPORT Source Type: research

Management of a pure uterine corpus rhabdomyosarcoma in a postmenopausal patient: A rare case report and review of the literature
Key Clinical MessageRhabdomyosarcoma of the female genital tract often involves the vagina and cervix. It usually occurs in infants and children. Such tumors are uncommon in the uterus, especially in adults. Treatment options are based on studies of younger individuals.AbstractRhabdomyosarcoma (RMS) is a malignant mesenchymal neoplasm with a tendency to differentiate into skeletal muscle cells. RMS is an aggressive tumor that tends to develop in children and younger patients. A vast majority of genital tract RMSs occur in the vagina and cervix. Such tumors rarely occur in adults. Usually, these tumors either occur as a com...
Source: Clinical Case Reports - March 7, 2024 Category: General Medicine Authors: John Lugata, Caleigh Smith, Onesmo Mrosso, Doris Rwenyagila, Baraka Shao, Alex Mremi Tags: CASE REPORT Source Type: research

Rapidly growing distal choroidal artery aneurysm re ‐rupture following revascularization for hemorrhagic Moyamoya disease: A case report
This report raises questions regarding the causes and management of unstable postbypass hemodynamics. (Source: Clinical Case Reports)
Source: Clinical Case Reports - March 7, 2024 Category: General Medicine Authors: Jeong Taek Yoon, Kyung Mi Lee, Jiwook Ryu, Ju In Park Tags: CASE REPORT Source Type: research

Migrated subcutaneous sharp foreign body in the anterior chest wall: An unusual presentation
Key Clinical MessageMigration of any foreign body can cause potentially life threatening complications and should be reviewed by a multidisciplinary approach for the management. Diagnosis can be challenging; a history of foreign body injury could be suspicious.AbstractForeign body injury to the chest wall can be an emergency situation and require a multidisciplinary approach for the management of the condition. Migration of the foreign body, though rare, can lead to potentially life threatening complications and require a multidisciplinary approach for the localization of the foreign body and subsequent management of the c...
Source: Clinical Case Reports - March 7, 2024 Category: General Medicine Authors: Shritik Devkota, Prajjwal Pokharel, Samiksha Lamichhane, Harsha Bhola, Tajinder Bhalla Tags: CASE REPORT Source Type: research

Massive hemoptysis with end stage renal disease (ESRD): An initial symptom of rare disease
Key Clinical MessageMicroscopic polyangiitis is a rare autoimmune vasculitis, that could present with renal-pulmonary symptoms, posing diagnostic challenges in patients with preexisting kidney disease. Timely diagnosis is crucial to improve patient outcomes. (Source: Clinical Case Reports)
Source: Clinical Case Reports - March 7, 2024 Category: General Medicine Authors: Sakditad Saowapa, Nattanicha Chaisrimaneepan, Yaw Adu, Jerapas Thongpiya, Pitchaporn Yingchoncharoen, Amanda L. Bell, Natchaya Polpichai, Pharit Siladech, J. Drew Payne Tags: CASE REPORT Source Type: research

Successful treatment of refractory prurigo nodularis with abrocitinib
Key Clinical MessagePrurigo nodularis is frequently difficult to manage with conventional therapy. Given the pathogenesis and refractory nature, we demonstrate a case in which inhibition of JAK –STAT signaling may significantly improve prurigo nodularis. Based on the results, we would like to draw a conclusion that abrocitinib as an inhibitor of Jak is a promising choice for the treatment of prurigo nodularis. (Source: Clinical Case Reports)
Source: Clinical Case Reports - March 7, 2024 Category: General Medicine Authors: Fang Sun, Zhenzhen Wu Tags: CASE REPORT Source Type: research

Cryoglobulinemia vasculitis associated with adult ‐onset Still's disease
Key Clinical MessageThe present case indicates that cryoglobulinemia vasculitis should be considered in the differential diagnosis of purpura in patients with adult-onset Still's disease (AOSD).AbstractThe presence of purpura is suggested in adult-onset Still's disease (AOSD) hematological complications of hemophagocytic syndrome, disseminated intravascular coagulation, or thrombotic microangiopathy. We herein report a case of AOSD complicated by cryoglobulinemia vasculitis presenting with purpura. (Source: Clinical Case Reports)
Source: Clinical Case Reports - March 7, 2024 Category: General Medicine Authors: Noriharu Nakagawa, Ai Fujii, Yoshimichi Ueda, Masahide Yamazaki Tags: CASE IMAGE Source Type: research