Duodenal gastrointestinal stromal tumor presenting with life ‐threatening upper GI bleeding in a young patient: A case report and literature review
We present a case of a 31-year-old male patient presented with massive active hemateme sis and melena with hemorrhagic shock. The patient presented with massive hematemesis and melena of 1 h duration. Endoscopy showed pulsating active bleeding from the third part of the duodenum which was difficult to manage via endoscopy. Histopathologic evaluation showed spindle cell type GIST. In traoperatively, there was a nodular mass with active bleeding on the third part of the duodenum. Duodenectomy with end-to-end anastomosis was done. Discharged with no postoperative complication and was put on imatinib. There are considerable ...
Source: Clinical Case Reports - April 18, 2024 Category: General Medicine Authors: Samuel Addisu Abera,
Amanuel Kassa Tadesse,
Kirubel Addisu Abera,
Kassa Berie Zegeye,
Mohammed Alemu Ibrahim,
Ashenafi Amsalu Feleke,
Cheru lilay Gebrehiwet,
Segenet Bizuneh Mengistu,
Hirut Tesfahun Alemu,
Yohannis Derbew Molla Tags: CASE REPORT Source Type: research
Waldmann's disease: Primary intestinal lymphangiectasia diagnosed by 99mTc ‐labeled albumin macroaggregate scintigraphy—A case report in an adult patient
Key Clinical MessageRare yet significant, this case sheds light on the uncommon presentation of Waldmann's disease in adults, showcasing the diagnostic challenges it poses. A multidisciplinary approach, integrating clinical, endoscopic, histological, and radiological evaluations, is crucial for accurate diagnosis and management. Further research is needed to deepen our understanding of this complex disorder.AbstractWaldmann's disease, or primary intestinal lymphangiectasia, is a rare disorder characterized by protein-losing enteropathy due to dilation and leakage of intestinal lymphatic vessels. Although typically diagnose...
Source: Clinical Case Reports - April 17, 2024 Category: General Medicine Authors: Alex Jos é Castellón Méndez,
Allan Bodán Campbell,
Victor Rosales Obregón,
Mohammed Zahran Tags: CASE REPORT Source Type: research
Marchiafava ‐Bignami disease: Prompt diagnosis made by magnetic resonance brain imaging
Key Clinical MessageMarchiafava-Bignami disease, a rare condition often associated with alcoholism, shows myelin degeneration with tissue necrosis specifically in the corpus callosum. Urgent application of magnetic resonance imaging could lead to prompt diagnosis.AbstractA 66-year-old male with habitual alcohol drink complained acute deterioration of left-side muscle weakness as initial presentation. On the arrival, the patient was confused, with stable vital sign and unremarkable pyramidal sign. Although several potential diagnoses could be considered, brain computed tomography did not provide diagnostic information, and ...
Source: Clinical Case Reports - April 17, 2024 Category: General Medicine Authors: Satori Akita,
Takeshi Takakuwa,
Kouji Kajinami Tags: CASE IMAGE Source Type: research
Respiratory distress in a neonate: Inflation of a third branchial anomaly with positive airway pressure
We present a case of an unknown third branchial anomaly that was diagnosed following inflation with continuous positive airway pressure (CPAP), which exacerbated the infant's respiratory distress. (Source: Clinical Case Reports)
Source: Clinical Case Reports - April 17, 2024 Category: General Medicine Authors: Chantal Li,
Jennifer M. Siu,
Mary ‐Angela Woodward,
Nikolaus E. Wolter Tags: CASE REPORT Source Type: research
Comment on case of benralizumab ‐induced exacerbations of chronic spontaneous urticaria
(Source: Clinical Case Reports)
Source: Clinical Case Reports - April 17, 2024 Category: General Medicine Authors: Mustafa Ilker Inan,
Yasemin Akgul Balaban Tags: LETTER TO THE EDITOR Source Type: research
Acute acalculous cholecystitis complicated by infectious mononucleosis caused by cytomegalovirus
Key Clinical MessageWhen seeing patients who present with atypical lymphocytes and abdominal pain without accompanying symptoms of pharyngitis or lymphadenopathy, acalculous cholecystitis caused by CMV infection should be considered as a differential diagnosis.AbstractA teenage man presented with a fever and epigastric pain. The patient tested positive for cytomegalovirus IgG and IgM. Abdominal ultrasonography and contrast-enhanced CT revealed hepatosplenomegaly and gallbladder wall thickening. MRI did not identify gallstones or tumorous lesions. He was diagnosed with infectious mononucleosis and acalculous cholecystitis c...
Source: Clinical Case Reports - April 17, 2024 Category: General Medicine Authors: Noriko Ide,
Risa Hirata,
So Motomura,
Masaki Tago Tags: CASE IMAGE Source Type: research
A case of Sj ögren's syndrome in which diffuse cystic lung lesions led to an accurate diagnosis
Key Clinical MessageEven in the absence of other symptoms or other pulmonary manifestations suggesting Sj ögren's syndrome (SS), it is necessary to include SS in the differential diagnosis of diffuse cystic lung disease (CLD).AbstractA case of SS that presented initially with diffuse CLD is reported. This case is considered rare because diffuse pulmonary cysts were observed in the early stage with few symptoms, only cysts were observed without other lung lesions on imaging, cyst formation was histologically considered to be alveolar loss, and airway lesions not observed on imaging were suspected based on lung function tes...
Source: Clinical Case Reports - April 17, 2024 Category: General Medicine Authors: Satomi Mizutani,
Hidehiko Kuribayashi,
Noriyuki Saeki,
Hideki Ito,
Yasutaka Nakamura,
Makoto Masuda,
Yoshito Kamio,
Masashi Kawamoto,
Tatsuji Enomoto Tags: CASE REPORT Source Type: research
Netherton syndrome —A therapeutic challenge in childhood
We describe an 8-year-old boy with genetically proven NS treated with intravenous immunoglobulin for recurrent skin and systemic infections from infancy, growth retardation, and associated erythroderma. Under this therapy, his skin status, infectious exacerbations, and quality of life all improved. Knowledge of the cytokine-mediated pathogenesis of NS and the development of new biologic drugs open new possibilities for NS patients. However, the different therapeutic options have been applied in a limited number of cases, and variable responses have been shown. Randomized controlled trials with a sufficient number of patien...
Source: Clinical Case Reports - April 17, 2024 Category: General Medicine Authors: Polina Kostova,
Guergana Petrova,
Martin Shahid,
Vera Papochieva,
Dimitrinka Miteva,
Ivelina Yordanova,
Kossara Drenovska,
Irena Bradinova,
Camila K. Janniger,
Robert A. Schwartz,
Snejina Vassileva Tags: CASE REPORT Source Type: research
Adjuvant therapy for rare rectal gastrointestinal stromal tumors: A case report
Key Clinical MessageAnorectal gastrointestinal stromal tumors are extremely rare, constituting less than 0.1% of rectal tumors. Surgical resection using a transanal wide excision followed by adjuvant therapy with tyrosine kinase inhibitors can be a successful treatment combination to remove the mass and prevent recurrence while preserving the integrity of the anal sphincter.AbstractGastrointestinal stromal tumors (GISTs) are a rare subset of neoplasms, accounting for about 1% –2% of primary gastrointestinal malignancies. The stomach is the most common site for GISTs, with anorectal GISTs being exceptionally rare, represe...
Source: Clinical Case Reports - April 17, 2024 Category: General Medicine Authors: Ting ‐Yi Chu,
Ta‐Wei Pu,
Chao‐Yang Chen Tags: CASE REPORT Source Type: research
Successful management of cervical tuberculosis and severe kyphosis using polyetheretherketone expandable cage and titanium plate: A case report
This report details the successful treatment of a 27-year-old male with cervical tuberculosis and severe kyphosis. Surgical intervention involved prevertebral abscess evacuation, C5-C7 corpectomy, and insertion of a PEEK expandable cage with an anterior titanium plate. Postoperative care included a Philadelphia collar, and follow-up demonstrated restored cervical alignment and stability. The use of PEEK-based surgical interventions, as demonstrated in this case, represents a significant evolution in managing complex cervical conditions. The successful outcome highlights the potential benefits of PEEK expandable cages in ad...
Source: Clinical Case Reports - April 17, 2024 Category: General Medicine Authors: Javeed Iqbal,
Muhammad Mohsin Khan,
Abdulnasser Thabet,
Kazim Mohammed,
Gianluca Scalia,
Bipin Chaurasia Tags: CASE REPORT Source Type: research
Denosumab ‐induced autoimmune hepatitis: Case report
This report described a patient not known to have a hepatic disease, found to have a drug-induced autoimmune hepatitis from denosumab. This is an unreported side effect, and here, we presented the possible predisposing factors and suggested monitoring parameters. (Source: Clinical Case Reports)
Source: Clinical Case Reports - April 17, 2024 Category: General Medicine Authors: Jawaher J. Alotaibi,
Bushra Albuqami,
Wadha Alotaibi,
Rawan M. Al Ghamdi,
Mohammed Alaskar,
Hadi Kuriry,
Nasser Almasri Tags: CASE REPORT Source Type: research
Single ‐dose ibuprofen induced Stevens–Johnson Syndrome
We present a case of a 45-year-old woman who developed SJS following a single dose of ibuprofen. Despite its rarity, this case underscores the importance of heightened vigilance in healthcare and public awareness regarding the potential risks of commonly used medications. Prompt recognition of SJS symptoms and immediate medical intervention are crucial for patient outcomes. Healthcare providers should exercise caution when prescribing ibuprofen, particu larly in patients with a history of adverse drug reactions. This case emphasizes the need for ongoing monitoring, patient education, and informed decision-making to promote...
Source: Clinical Case Reports - April 16, 2024 Category: General Medicine Authors: Ahmed Qasim Mohammed Alhatemi,
Hashim Talib Hashim,
Muhamad Abdulrahman Shyea Al ‐Tarbosh,
Rand Abdulhussain,
Ali Talib Hashim Tags: CASE REPORT Source Type: research
Cystic meningiomas: A complex diagnostic challenge and clinicopathological insights from a unique case presentation
Key Clinical MessageMeningiomas present diverse clinical and radiological characteristics, with cystic formations constituting a lesser subset but posing significant diagnostic hurdles. We explore the complexities of cystic meningiomas through a distinctive case, highlighting the challenges in diagnosis and management due to their variable presentations. A 54-year-old female from Bengaluru, Karnataka, initially presented with transient memory disturbances. Brain MRI revealed a sizable left frontal cystic lesion exerting a mass effect and midline shift. However, rapid neurological decline led to an urgent surgical intervent...
Source: Clinical Case Reports - April 15, 2024 Category: General Medicine Authors: Deepa Singh,
Gianluca Scalia,
Veeresh U. Mathand,
Bipin Chaurasia Tags: CASE REPORT Source Type: research
Osteoblastoma of the frontal sinus: A rare case presenting with seizures and pneumocephalus
We present a case of osteoblastoma located in the frontal sinus, an exceptionally uncommon site, resulting in seizures secondary to pneumocephalus. A 21-year-old male presented with a generalized tonic –clonic seizure and postictal confusion. Imaging studies revealed a well-defined lesion in the left frontal sinus causing cortical breach, destruction of the posterior wall, and pneumocephalus. A total surgical excision was performed through bifrontal craniotomy. Histopathological analysis confirm ed the diagnosis of osteoblastoma. Postoperative recovery was uneventful, with a follow-up CT scan showing complete lesion exci...
Source: Clinical Case Reports - April 15, 2024 Category: General Medicine Authors: Dattatraya Mallik,
Nandyal Chandrashekhar,
Abhishek Kumar Rai,
Saransh Dhingra,
Gaurav Arora,
Sapan Gandhi,
Gianluca Scalia,
Bipin Chaurasia Tags: CASE REPORT Source Type: research
A case of celiac plexus block causing iatrogenic Cushing's syndrome
Key Clinical MessageTreatment with corticosteroids can lead to iatrogenic Cushing's syndrome when used for longer intervals and in high doses. Less common administration routes may conceal the exposure, raising the possibility of misdiagnosis and mismanagement. (Source: Clinical Case Reports)
Source: Clinical Case Reports - April 15, 2024 Category: General Medicine Authors: Ana ‐Maria Chindris,
Sarika N. Rao,
Razvan M. Chirila,
Adrian G. Dumitrascu Tags: CASE REPORT Source Type: research
