Nonlinear relationship between untraditional lipid parameters and the risk of prediabetes: a large retrospective study based on Chinese adults
Abnormal lipid metabolism poses a risk for prediabetes. However, research on lipid parameters used to predict the risk of prediabetes is scarce, and the significance of traditional and untraditional lipid para... (Source: Cardiovascular Diabetology)
Source: Cardiovascular Diabetology - January 6, 2024 Category: Cardiology Authors: Mingkang Li, Wenkang Zhang, Minhao Zhang, Linqing Li, Dong Wang, Gaoliang Yan, Yong Qiao and Chengchun Tang Tags: Research Source Type: research

Triglyceride-glucose index as a suitable non-insulin-based insulin resistance marker to predict cardiovascular events in patients undergoing complex coronary artery intervention: a large-scale cohort study
Insulin resistance (IR), a hallmark of proceeding diabetes and cardiovascular (CV) disease, has been shown to predict prognosis in patients undergoing percutaneous coronary intervention (PCI). The triglyceride... (Source: Cardiovascular Diabetology)
Source: Cardiovascular Diabetology - January 6, 2024 Category: Cardiology Authors: Jining He, Chenxi Song, Sheng Yuan, Xiaohui Bian, Zhangyu Lin, Min Yang and Kefei Dou Tags: Research Source Type: research

Association between the cumulative average triglyceride glucose-body mass index and cardiovascular disease incidence among the middle-aged and older population: a prospective nationwide cohort study in China
Findings from earlier research have established that insulin resistance (IR) is implicated in atherosclerosis progression, representing a noteworthy risk factor for cardiovascular disease (CVD). Recently, the ... (Source: Cardiovascular Diabetology)
Source: Cardiovascular Diabetology - January 6, 2024 Category: Cardiology Authors: Fadong Li, Yue Wang, Boqun Shi, Shuaifeng Sun, Shen Wang, Shuo Pang and Xiaofan Wu Tags: Research Source Type: research

Semaglutide modulates prothrombotic and atherosclerotic mechanisms, associated with epicardial fat, neutrophils and endothelial cells network
Obesity has increased in recent years with consequences on diabetes and other comorbidities. Thus, 1 out of 3 diabetic patients suffers cardiovascular disease (CVD). The network among glucose, immune system, e... (Source: Cardiovascular Diabetology)
Source: Cardiovascular Diabetology - January 3, 2024 Category: Cardiology Authors: David Garc ía-Vega, David Sánchez-López, Gemma Rodríguez-Carnero, Rocío Villar-Taibo, Juan E. Viñuela, Adán Lestegás-Soto, Ana Seoane-Blanco, María Moure-González, Susana B. Bravo, Ángel L. Fernández, José R. González-Juanatey and Sonia Eira Tags: Research Source Type: research

Central and peripheral blood pressures in relation to the triglyceride-glucose index in a Chinese population
The triglyceride-glucose (TyG) index has been proposed as a surrogate marker of insulin resistance. However, the relationship between the TyG index and central blood pressure (BP), has not been well studied in... (Source: Cardiovascular Diabetology)
Source: Cardiovascular Diabetology - January 3, 2024 Category: Cardiology Authors: Yin-Hua Sun, Nai-Qing Hu, Xian-Yi Huang, Zheng-Xin Liu, Qi-Yan Li, Qing-Lu Li and Li-Hua Li Tags: Research Source Type: research

Impact of PCSK9 inhibitors in glycaemic control and new-onset diabetes
The diabetogenic effect of statins has been well established by clinical trials, Mendelian randomisation studies and meta-analyses. According to large clinical trials, PCSK9 inhibitors (PCSK9i) have no deleter... (Source: Cardiovascular Diabetology)
Source: Cardiovascular Diabetology - January 3, 2024 Category: Cardiology Authors: Ana M. Gonz ález-Lleó, Rosa M. Sánchez-Hernández, Núria Plana, Daiana Ibarretxe, Pere Rehues, Josep Ribalta, Dídac Llop, Ana M. Wägner, Lluís Masana and Mauro Boronat Tags: Research Source Type: research

Relationship between triglyceride-glucose index baselines and trajectories with incident cardiovascular diseases in the elderly population
The triglyceride-glucose (TyG) index is regarded as a sophisticated surrogate biomarker for insulin resistance, offering a refined means for evaluating cardiovascular diseases (CVDs). However, prospective coho... (Source: Cardiovascular Diabetology)
Source: Cardiovascular Diabetology - January 3, 2024 Category: Cardiology Authors: Yue Wang, Xueyu Chen, Jie Shi, Mingyi Du, Shengnan Li, Jinhong Pang, Junpeng Qiao, Yingying Zhao, Qiaoqiao Chen, Yuanyuan Guo, Yan Xi and Weiwei Chi Tags: Research Source Type: research

Association of long-term triglyceride-glucose index patterns with the incidence of chronic kidney disease among non-diabetic population: evidence from a functional community cohort
The triglyceride-glucose (TyG) index is a reliable surrogate marker of insulin resistance and previous studies have confirmed the association of TyG index with incident chronic kidney disease (CKD). However, t... (Source: Cardiovascular Diabetology)
Source: Cardiovascular Diabetology - January 3, 2024 Category: Cardiology Authors: Ning Chen, Lin-Lin Ma, Yu Zhang, Xi Chu, Jing Dong and Yu-Xiang Yan Tags: Research Source Type: research

Long-term effects of blood pressure 130 –139/80–89 mmHg on all-cause and cardiovascular mortality among Chinese adults with different glucose metabolism
This study aimed to investigate the risks of all-cause and cardiovascular mortality associated with blood pressure (BP) levels of 130 –139/80–89 mmHg in Chinese adults with different glucose metabolism, during ... (Source: Cardiovascular Diabetology)
Source: Cardiovascular Diabetology - December 21, 2023 Category: Cardiology Authors: Chang-Sheng Sheng, Haiyan Wang, Yanjun Liu, Yanyun Li, TianZhiChao Hou, Miaoyan Qiu, Yao Lu, Siming Sun, Junhan Yang, Xiaomin Song, Guang Ning and Jingyan Tian Tags: Research Source Type: research

Combined effect of adiposity and elevated inflammation on incident type 2 diabetes: a prospective cohort study
Adiposity and elevated inflammation are two hallmarks of hyperglycemia. However, it is unknown whether clustering of elevated inflammation and adiposity interact act on diabetogenesis and lead to a greater ris... (Source: Cardiovascular Diabetology)
Source: Cardiovascular Diabetology - December 20, 2023 Category: Cardiology Authors: Dan Wu, Yulong Lan, Shuohua Chen, Xiong Ding, Guanzhi Chen, Chutao Wu, Lois Balmer, Wencan Xu, Shouling Wu and Wei Wang Tags: Research Source Type: research

Primary aldosteronism and lower-extremity arterial disease: a two-sample Mendelian randomization study
Primary aldosteronism (PA) is an adrenal disorder of autonomous aldosterone secretion which promotes arterial injury. We aimed to explore whether PA is causally associated with lower-extremity arterial disease... (Source: Cardiovascular Diabetology)
Source: Cardiovascular Diabetology - December 20, 2023 Category: Cardiology Authors: Jinbo Hu, Qinglian Zeng, Xiangjun Chen, Wenjin Luo, Ziwei Tang, Mei Mei, Wenrui Zhao, Zhipeng Du, Zhiping Liu, Qifu Li, Qingfeng Cheng and Shumin Yang Tags: Research Source Type: research

Dapagliflozin treatment is associated with a reduction of epicardial adipose tissue thickness and epicardial glucose uptake in human type 2 diabetes
We recently demonstrated that treatment with sodium-glucose cotransporter-2 inhibitors (SGLT-2i) leads to an increase in myocardial flow reserve in patients with type 2 diabetes (T2D) with stable coronary arte... (Source: Cardiovascular Diabetology)
Source: Cardiovascular Diabetology - December 19, 2023 Category: Cardiology Authors: Francesca Cinti, Lucia Leccisotti, Gian Pio Sorice, Umberto Capece, Domenico D ’Amario, Margherita Lorusso, Shawn Gugliandolo, Cassandra Morciano, Andrea Guarneri, Maria Angela Guzzardi, Teresa Mezza, Amedeo Capotosti, Luca Indovina, Pietro Manuel Ferra Tags: Research Source Type: research

Early insulin resistance in normoglycemic low-risk individuals is associated with subclinical atherosclerosis
Elevated glycated hemoglobin (HbA1c) is associated with a higher burden of subclinical atherosclerosis (SA). However, the association with SA of earlier insulin resistance markers is poorly understood. The stu... (Source: Cardiovascular Diabetology)
Source: Cardiovascular Diabetology - December 19, 2023 Category: Cardiology Authors: Josep Iglesies-Grau, Ana Garcia-Alvarez, Bel én Oliva, Guiomar Mendieta, Inés García-Lunar, José J. Fuster, Ana Devesa, Cristina Pérez-Herreras, Antonio Fernández-Ortiz, Ramon Brugada, Borja Ibanez, Rodrigo Fernandez-Jimenez and Valentin Fuster Tags: Research Source Type: research

Prediabetes increases the risk of major limb and cardiovascular events
Prediabetes, an intermediate stage between normal blood sugar levels and a diabetes mellitus diagnosis, is increasing in prevalence. Severe prediabetes is associated with a similar risk of complications as dia... (Source: Cardiovascular Diabetology)
Source: Cardiovascular Diabetology - December 19, 2023 Category: Cardiology Authors: Jung-Chi Hsu, Yen-Yun Yang, Shu-Lin Chuang, Jen-Kuang Lee and Lian-Yu Lin Tags: Research Source Type: research

The triglyceride glucose index trajectory is associated with hypertension: a retrospective longitudinal cohort study
Previous studies have found that the triglyceride glucose index (TyG index) trajectories are associated with cardiovascular diseases. However, the association between the patterns of TyG index trajectories and... (Source: Cardiovascular Diabetology)
Source: Cardiovascular Diabetology - December 15, 2023 Category: Cardiology Authors: Fengling Xin, Shuyou He, Yu Zhou, Xueni Jia, Yulong Zhao and Hui Zhao Tags: Research Source Type: research