Transitioning from having no metabolic abnormality nor obesity to metabolic impairment in a cohort of apparently healthy adults
The global prevalence of metabolic syndrome and its association with increased morbidity and mortality has been rigorously studied. However, the true prevalence of “metabolic health”, i.e. individuals without ... (Source: Cardiovascular Diabetology)
Source: Cardiovascular Diabetology - August 26, 2023 Category: Cardiology Authors: Hadas Ben-Assayag, Rafael Y. Brzezinski, Shlomo Berliner, David Zeltser, Itzhak Shapira, Ori Rogowski, Sharon Toker, Roy Eldor and Shani Shenhar-Tsarfaty Tags: Research Source Type: research

Comprehensive transcriptomics and metabolomics analyses reveal that hyperhomocysteinemia is a high risk factor for coronary artery disease in a chinese obese population aged 40 –65: a prospective cross-sectional study
This study aimed to characterize the intermediate metabolism phenotypes among obese patients with CAD and... (Source: Cardiovascular Diabetology)
Source: Cardiovascular Diabetology - August 24, 2023 Category: Cardiology Authors: Chong-Yu Zhang, Ru-Qin Xu, Xiao-Qiao Wang, Lin-Feng Sun, Pei Mo, Ren-Jie Cai, Xiao-Zhen Lin, Cheng-Feng Luo, Wen-Chao Ou, Lie-Jing Lu, Yun Zhong and Jia-Yuan Chen Tags: Research Source Type: research

Effect of semaglutide on major adverse cardiovascular events by baseline kidney parameters in participants with type 2 diabetes and at high risk of cardiovascular disease: SUSTAIN 6 and PIONEER 6 post hoc pooled analysis
Semaglutide is a glucose-lowering treatment for type 2 diabetes (T2D) with demonstrated cardiovascular benefits; semaglutide may also have kidney-protective effects. This post hoc analysis investigated the associ... (Source: Cardiovascular Diabetology)
Source: Cardiovascular Diabetology - August 24, 2023 Category: Cardiology Authors: Peter Rossing, Stephen C. Bain, Heidrun Bosch-Traberg, Ekaterina Sokareva, Hiddo J. L. Heerspink, S øren Rasmussen and Linda G. Mellbin Tags: Research Source Type: research

Impact of early postoperative blood glucose variability on serum endocan level in cardiac surgery patients: a sub study of the ENDOLUNG observational study
This study aimed to describe the relationship between postoperativ... (Source: Cardiovascular Diabetology)
Source: Cardiovascular Diabetology - August 24, 2023 Category: Cardiology Authors: Etienne Chazal, Lucas Morin, Sidney Chocron, Philippe Lassalle, Sebastien Pili-Floury, Lucie Salomon du Mont, David Ferreira, Emmanuel Samain, Andrea Perrotti and Guillaume Besch Tags: Research Source Type: research

Prognostic value of high-sensitivity C-reactive protein in patients undergoing percutaneous coronary intervention with different glycemic metabolism status
High-sensitivity C-reaction protein (hsCRP), a biomarker of residual inflammatory risk, has been demonstrated with poor cardiovascular outcomes. We aimed to investigate the prognostic value of hsCRP in patient... (Source: Cardiovascular Diabetology)
Source: Cardiovascular Diabetology - August 24, 2023 Category: Cardiology Authors: Le Li, Shangyu Liu, Zhuxin Zhang, Likun Zhou, Zhenhao Zhang, Yulong Xiong, Zhao Hu and Yan Yao Tags: Research Source Type: research

The triglyceride-glucose index is associated with atherosclerosis in patients with symptomatic coronary artery disease, regardless of diabetes mellitus and hyperlipidaemia
Diabetes and hyperlipidaemia are both risk factors for coronary artery disease, and both are associated with a high triglyceride-glucose index (TyG index). The TyG index has been presented as a marker of insul... (Source: Cardiovascular Diabetology)
Source: Cardiovascular Diabetology - August 24, 2023 Category: Cardiology Authors: Jiao Li, Zixian Dong, Hao Wu, Yue Liu, Yafang Chen, Si Li, Yufan Zhang, Xin Qi and Liping Wei Tags: Research Source Type: research

Early vascular aging as an index of cardiovascular risk in healthy adults: confirmatory factor analysis from the EVasCu study
The concept of early vascular aging (EVA) represents a potentially beneficial model for future research into the pathophysiological mechanisms underlying the early manifestations of cardiovascular disease. For... (Source: Cardiovascular Diabetology)
Source: Cardiovascular Diabetology - August 17, 2023 Category: Cardiology Authors: Alicia Saz-Lara, Iv án Cavero-Redondo, Carlos Pascual-Morena, Irene Martínez-García, Eva Rodríguez-Gutiérrez, Maribel Lucerón-Lucas-Torres, Bruno Bizzozero-Peroni, Nerea Moreno-Herráiz and Arturo Martínez-Rodrigo Tags: Research Source Type: research

Association between cumulative atherogenic index of plasma exposure and risk of myocardial infarction in the general population
Atherogenic index of plasma (AIP) has been confirmed as a novel marker for myocardial infarction (MI), but few evidence on the long-term AIP and MI risk in general populations. We thus aimed to evaluate the re... (Source: Cardiovascular Diabetology)
Source: Cardiovascular Diabetology - August 17, 2023 Category: Cardiology Authors: Yijun Zhang, Shuohua Chen, Xue Tian, Penglian Wang, Qin Xu, Xue Xia, Xiaoli Zhang, Jing Li, Fen Liu, Shouling Wu and Anxin Wang Tags: Research Source Type: research

Clusters of prediabetes and type 2 diabetes stratify all-cause mortality in a cohort of participants undergoing invasive coronary diagnostics
Heterogeneous metabolic clusters have been identified in diabetic and prediabetic states. It is not known whether such pathophysiologic clusters impact survival in at-risk persons being evaluated for coronary ... (Source: Cardiovascular Diabetology)
Source: Cardiovascular Diabetology - August 17, 2023 Category: Cardiology Authors: Katsiaryna Prystupa, Graciela E. Delgado, Angela P. Moissl, Marcus E. Kleber, Andreas L. Birkenfeld, Martin Heni, Andreas Fritsche, Winfried M ärz and Robert Wagner Tags: Research Source Type: research

A six-month low-carbohydrate diet high in fat does not adversely affect endothelial function or markers of low-grade inflammation in patients with type 2 diabetes: an open-label randomized controlled trial
While a low-carbohydrate diet (LCD) reduces HbA1c in patients with type 2 diabetes (T2D), the associated high intake of fat may adversely affect cardiovascular risk factors. To address this, we examined the ef... (Source: Cardiovascular Diabetology)
Source: Cardiovascular Diabetology - August 17, 2023 Category: Cardiology Authors: Eva M. Gram-Kampmann, Thomas B. Olesen, Camilla D. Hansen, Mie B. Hugger, Jane M. Jensen, Aase Handberg, Henning Beck-Nielsen, Aleksander Krag, Michael H. Olsen and Kurt H øjlund Tags: Research Source Type: research

GIP receptor agonism improves dyslipidemia and atherosclerosis independently of body weight loss in preclinical mouse model for cardio-metabolic disease
Agonism at the receptor for the glucose-dependent insulinotropic polypeptide (GIPR) is a key component of the novel unimolecular GIPR:GLP-1R co-agonists, which are among the most promising drugs in clinical de... (Source: Cardiovascular Diabetology)
Source: Cardiovascular Diabetology - August 17, 2023 Category: Cardiology Authors: Stephan Sachs, Anna G ötz, Brian Finan, Annette Feuchtinger, Richard D. DiMarchi, Yvonne Döring, Christian Weber, Matthias H. Tschöp, Timo D. Müller and Susanna M. Hofmann Tags: Research Source Type: research

Empagliflozin improves insulin sensitivity in patients with recent acute coronary syndrome and newly detected dysglycaemia
Empagliflozin reduces the risk of cardiovascular disease (CVD) in patients with type 2 diabetes (T2DM) and high cardiovascular risk via mechanisms which have not been fully explained. The mechanisms of such be... (Source: Cardiovascular Diabetology)
Source: Cardiovascular Diabetology - August 11, 2023 Category: Cardiology Authors: Elena Fortin, Magnus Lundin, Linda Mellbin, Anna Norhammar, Per N äsman, Stina Smetana, Peder Sörensson, Ele Ferrannini, Lars Rydén and Giulia Ferrannini Tags: Research Source Type: research

Elevated urine albumin creatinine ratio increases cardiovascular mortality in coronary artery disease patients with or without type 2 diabetes mellitus: a multicenter retrospective study
Albuminuria has been suggested as an atherosclerotic risk factor among the general population. However, whether this association will be amplified in patients with coronary artery disease (CAD) is unknown. It ... (Source: Cardiovascular Diabetology)
Source: Cardiovascular Diabetology - August 10, 2023 Category: Cardiology Authors: Xueqin Lin, Wei Song, Yang Zhou, Yuwei Gao, Yani Wang, Yun Wang, Yuchen Liu, Lin Deng, Yin Liao, Bo Wu, Shiqun Chen, Liling Chen and Yong Fang Tags: Research Source Type: research

Hepatic steatosis with significant fibrosis is associated with an increased 10-year estimated risk of cardiovascular disease in adults with type 1 diabetes mellitus
We assessed whether hepatic steatosis with or without significant fibrosis (determined by validated non-invasive biomarkers) is associated with an increased 10-year estimated risk for cardiovascular disease (C... (Source: Cardiovascular Diabetology)
Source: Cardiovascular Diabetology - August 10, 2023 Category: Cardiology Authors: Alessandro Mantovani, Mario Luca Morieri, Luisa Palmisano, Maria Masulli, Efisio Cossu, Marco Giorgio Baroni, Katia Bonomo, Flavia Agata Cimini, Gisella Cavallo, Raffaella Buzzetti, Carmen Mignogna, Frida Leonetti, Simonetta Bacci, Roberto Trevisan, Ricca Tags: Research Source Type: research

Nonlinear relationship between atherogenic index of plasma and the risk of prediabetes: a retrospective study based on Chinese adults
The atherogenic index of plasma (AIP) can reflect the burden of atherosclerosis. Hyperglycemia is one of the leading causes of atherosclerosis. However, the relationship between AIP and prediabetes is rarely s... (Source: Cardiovascular Diabetology)
Source: Cardiovascular Diabetology - August 10, 2023 Category: Cardiology Authors: Xiaodan Zheng, Xin Zhang, Yong Han, Haofei Hu and Changchun Cao Tags: Research Source Type: research