Risk factors for and risk of all-cause and atherosclerotic cardiovascular disease mortality in people with type 2 diabetes and peripheral artery disease: an observational, register-based cohort study
Type 2 diabetes (T2D) and peripheral artery disease (PAD) are recognized as independent risk factors contributing to excess mortality. Contemporary observational studies exploring the associations of risk fact... (Source: Cardiovascular Diabetology)
Source: Cardiovascular Diabetology - April 15, 2024 Category: Cardiology Authors: Tarik Avdic, Hanne K. Carlsen, Aidin Rawshani, Soffia Gudbj örnsdottir, Zacharias Mandalenakis and Björn Eliasson Tags: Research Source Type: research
Relationships of serum FGF23 and α-klotho with atherosclerosis in patients with type 2 diabetes mellitus
Compelling evidence suggests that calcium/phosphorus homeostasis-related parameters may be linked to diabetes mellitus and cardiovascular events. However, few studies have investigated the association of fibro... (Source: Cardiovascular Diabetology)
Source: Cardiovascular Diabetology - April 15, 2024 Category: Cardiology Authors: Jiao Bi, Mei Zheng, Ke Li, Siwei Sun, Zihang Zhang, Nana Yan and Xueping Li Tags: Research Source Type: research
Circ_005077 accelerates myocardial lipotoxicity induced by high-fat diet via CyPA/p47PHOX mediated ferroptosis
The long-term high-fat diet (HFD) can cause myocardial lipotoxicity, which is characterized pathologically by myocardial hypertrophy, fibrosis, and remodeling and clinically by cardiac dysfunction and heart fa... (Source: Cardiovascular Diabetology)
Source: Cardiovascular Diabetology - April 15, 2024 Category: Cardiology Authors: Xinzhu Ni, Lian Duan, Yandong Bao, Jinyang Li, Xiaowen Zhang, Dalin Jia and Nan Wu Tags: Research Source Type: research
Clinically relevant plasma proteome for adiposity depots: evidence from systematic mendelian randomization and colocalization analyses
The accumulation of visceral and ectopic fat comprise a major cause of cardiometabolic diseases. However, novel drug targets for reducing unnecessary visceral and ectopic fat are still limited. Our study aims ... (Source: Cardiovascular Diabetology)
Source: Cardiovascular Diabetology - April 13, 2024 Category: Cardiology Authors: Min Cao and Bin Cui Tags: Research Source Type: research
Factors influencing hospitalization or emergency department visits and mortality in type 2 diabetes following the onset of new cardiovascular diagnoses in a population-based study
This study aimed to identi... (Source: Cardiovascular Diabetology)
Source: Cardiovascular Diabetology - April 10, 2024 Category: Cardiology Authors: Bj örn Agvall, Junmei Miao Jonasson, Alexander Galozy and Anders Halling Tags: Research Source Type: research
Frail hypertensive older adults with prediabetes and chronic kidney disease: insights on organ damage and cognitive performance - preliminary results from the CARYATID study
Hypertension and chronic kidney disease (CKD) pose significant public health challenges, sharing intertwined pathophysiological mechanisms. Prediabetes is recognized as a precursor to diabetes and is often acc... (Source: Cardiovascular Diabetology)
Source: Cardiovascular Diabetology - April 10, 2024 Category: Cardiology Authors: Gaetano Santulli, Valeria Visco, Michele Ciccarelli, Mario Nicola Vittorio Ferrante, Piero De Masi, Antonella Pansini, Nicola Virtuoso, Armando Pirone, Germano Guerra, Veronica Verri, Gaetano Macina, Alessandro Taurino, Klara Komici and Pasquale Mone Tags: Research Source Type: research
Association between triglyceride –glucose index trajectories and radiofrequency ablation outcomes in patients with stage 3D atrial fibrillation
This study investigates the relationship between triglyceride-glucose (TyG) index trajectories and the results of ablation in patients with stage 3D atrial fibrillation (AF). (Source: Cardiovascular Diabetology)
Source: Cardiovascular Diabetology - April 5, 2024 Category: Cardiology Authors: Sixiang Jia, Yanping Yin, Xuanting Mou, Jing Zheng, Zhe Li, Tianli Hu, Jianqiang Zhao, Jiangbo Lin, Jiaqi Song, Fanli Cheng, Yiran Wang, Kaini Li, Wenting Lin, Chao Feng, Weili Ge and Shudong Xia Tags: Research Source Type: research
Repressive H3K27me3 drives hyperglycemia-induced oxidative and inflammatory transcriptional programs in human endothelium
Histone modifications play a critical role in chromatin remodelling and regulate gene expression in health and disease. Histone methyltransferases EZH1, EZH2, and demethylases UTX, JMJD3, and UTY catalyse trim... (Source: Cardiovascular Diabetology)
Source: Cardiovascular Diabetology - April 5, 2024 Category: Cardiology Authors: Julia S ánchez-Ceinos, Shafaat Hussain, Abdul Waheed Khan, Liang Zhang, Wael Almahmeed, John Pernow and Francesco Cosentino Tags: Research Source Type: research
Oral-gut microbial transmission promotes diabetic coronary heart disease
This study aims to unravel the distinct characteristics of oral and gut microbiota in diabetic coronary heart disease (DCHD). Simultaneous... (Source: Cardiovascular Diabetology)
Source: Cardiovascular Diabetology - April 5, 2024 Category: Cardiology Authors: Yiwen Li, Yanfei Liu, Jing Cui, Mengmeng Zhu, Wenting Wang, Keji Chen, Luqi Huang and Yue Liu Tags: Research Source Type: research
Irisin attenuates type 1 diabetic cardiomyopathy by anti-ferroptosis via SIRT1-mediated deacetylation of p53
Diabetic cardiomyopathy (DCM) is a serious complication in patients with type 1 diabetes mellitus (T1DM), which still lacks adequate therapy. Irisin, a cleavage peptide off fibronectin type III domain-containi... (Source: Cardiovascular Diabetology)
Source: Cardiovascular Diabetology - April 2, 2024 Category: Cardiology Authors: Yuan-juan Tang, Zhen Zhang, Tong Yan, Ken Chen, Guo-fan Xu, Shi-qiang Xiong, Dai-qian Wu, Jie Chen, Pedro A. Jose, Chun-yu Zeng and Jin-juan Fu Tags: Research Source Type: research
The neutrophil-to-lymphocyte ratio is associated with all-cause and cardiovascular mortality among individuals with hypertension
Identifying reliable prognostic markers is crucial for the effective management of hypertension. The neutrophil-to-lymphocyte ratio (NLR) has emerged as a potential inflammatory marker linked to cardiovascular... (Source: Cardiovascular Diabetology)
Source: Cardiovascular Diabetology - April 2, 2024 Category: Cardiology Authors: Xuexue Zhang, Rui Wei, Xujie Wang, Wantong Zhang, Mengxuan Li, Tian Ni, Weiliang Weng and Qiuyan Li Tags: Research Source Type: research
Sodium-glucose cotransporter 2 inhibitors, inflammation, and heart failure: a two-sample Mendelian randomization study
Sodium-glucose cotransporter 2 (SGLT-2) inhibitors are increasingly recognized for their role in reducing the risk and improving the prognosis of heart failure (HF). However, the precise mechanisms involved re... (Source: Cardiovascular Diabetology)
Source: Cardiovascular Diabetology - April 2, 2024 Category: Cardiology Authors: Wenqin Guo, Lingyue Zhao, Weichao Huang, Jing Chen, Tingting Zhong, Shaodi Yan, Wei Hu, Fanfang Zeng, Changnong Peng and Hongbing Yan Tags: Research Source Type: research
The association of atherogenic index of plasma with cardiovascular outcomes in patients with coronary artery disease: A systematic review and meta-analysis
Atherogenic index of plasma (AIP) represents a novel marker in the current era of cardiovascular diseases. In this meta-analysis, we aimed to evaluate the association of AIP with cardiovascular prognosis in pa... (Source: Cardiovascular Diabetology)
Source: Cardiovascular Diabetology - April 2, 2024 Category: Cardiology Authors: Mehrdad Rabiee Rad, Ghazal Ghasempour Dabaghi, Bahar Darouei and Reza Amani-Beni Tags: Review Source Type: research
The effect of hyperlipidemia and body fat distribution on subclinical left ventricular function in obesity: a cardiovascular magnetic resonance study
Obesity is often associated with multiple comorbidities. However, whether obese subjects with hyperlipidemia in the absence of other complications have worse cardiac indices than metabolically healthy obese su... (Source: Cardiovascular Diabetology)
Source: Cardiovascular Diabetology - April 2, 2024 Category: Cardiology Authors: Jing Liu, Jing Li, Chunchao Xia, Wenzhang He, Xue Li, Sumin Shen, Xiaoyue Zhou, Nanwei Tong and Liqing Peng Tags: Research Source Type: research
Sex-specific trends in incidence of first myocardial infarction among people with and without diabetes between 1985 and 2016 in a German region
The reduction of myocardial infarction (MI) and narrowing the gap between the populations with and without diabetes are important goals of diabetes care. We analyzed time trends for sex-specific incidence rate... (Source: Cardiovascular Diabetology)
Source: Cardiovascular Diabetology - March 30, 2024 Category: Cardiology Authors: Heiner Claessen, Maria Narres, Margit Heier, Tatjana Kvitkina, Birgit Linkohr, Georg Wolff, Michael Roden, Andrea Icks and Annette Peters Tags: Research Source Type: research
