Interactions of obesity, body shape, diabetes and sex steroids with respect to prostate cancer risk in the UK Biobank cohort
ConclusionsObesity and diabetes showed synergistic inverse associations with prostate cancer risk, likely involving testosterone reduction for diabetes and oestrogen generation for obesity, which were attenuated for high-ABSI. HI and SHBG showed synergistic inverse associations with prostate cancer risk. (Source: Cancer Medicine)
Source: Cancer Medicine - January 18, 2024 Category: Cancer & Oncology Authors: Sofia Christakoudi,
Konstantinos K. Tsilidis,
Evangelos Evangelou,
Elio Riboli Tags: RESEARCH ARTICLE Source Type: research
Incidence, clinical features, and survival outcomes of primary malignant lacrimal gland tumors: A population ‐based analysis
ConclusionsAlthough primary MLGT is rare, its incidence has steadily increased in the past 46 years, and surgery was related to a better prognosis. (Source: Cancer Medicine)
Source: Cancer Medicine - January 17, 2024 Category: Cancer & Oncology Authors: Lin ‐feng He,
Jin‐di Zhang,
Teng‐fei Zhu,
Peng‐cheng Zhao,
Pei Mou,
Shi‐yi Tang Tags: RESEARCH ARTICLE Source Type: research
Unveiling the potential anti ‐cancer activity of calycosin against multivarious cancers with molecular insights: A promising frontier in cancer research
ConclusionCalycosin exhibits excellent potential as a therapeutic drug against several cancer types and should be consumed until standard chemotherapeutics are available in pharma markets. (Source: Cancer Medicine)
Source: Cancer Medicine - January 17, 2024 Category: Cancer & Oncology Authors: Md Sohel,
Fatema Tuj Zahra Shova,
Shahporan shuvo,
Taiyara Mahjabin,
Md. Mojnu Mia,
Dibyendu Halder,
Hafizul Islam,
Md Roman Mogal,
Partha Biswas,
Hasi Rani Saha,
Bidhan Chandra Sarkar,
Abdullah Al Mamun Tags: REVIEW Source Type: research
The adverse characteristics of hepatocellular carcinoma in the non ‐cirrhotic liver disproportionately disadvantage Black patients
ConclusionsNon-cirrhotic patients had more advanced HCC than cirrhotic patients. Black patients (with or without cirrhosis) had more advanced HCC than comparable non-Black patients and higher mortality rates. Improved access to healthcare (commercial insurance) may increase early diagnosis (within Milan criteria) and reduce disparities. (Source: Cancer Medicine)
Source: Cancer Medicine - January 17, 2024 Category: Cancer & Oncology Authors: Tali Shaltiel,
Umut Sarpel,
Andrea D. Branch Tags: RESEARCH ARTICLE Source Type: research
Phenotype analysis of families with TP53 germline variants at the Center for Familial Breast and Ovarian Cancer, Cologne
ConclusionThe tumor spectrum and age of onset found in this study showed that tumors other than BC had low disease penetrance inTP53 PV carriers identified using the GC-HBOC criteria for genetic testing. (Source: Cancer Medicine)
Source: Cancer Medicine - January 17, 2024 Category: Cancer & Oncology Authors: K. Kast,
K. Rhiem,
M. Larsen,
B. Wappenschmidt,
R. Schmutzler Tags: RESEARCH ARTICLE Source Type: research
