Docetaxel, cisplatin, and fluorouracil with pegfilgrastim on day 3 as neoadjuvant chemotherapy for esophageal cancer
ConclusionAdministration of pegfilgrastim on day 3 was not sufficient to prevent FN due to DCF treatment, and prophylactic administration of both pegfilgrastim and antibiotics could be a solution. (Source: Cancer Medicine)
Source: Cancer Medicine - February 1, 2024 Category: Cancer & Oncology Authors: Osamu Maeda, Satoshi Furune, Mitsuro Kanda, Kazushi Miyata, Dai Shimizu, Shizuki Sugita, Kazuki Nishida, Masahiko Ando, Yasuhiro Kodera, Yuichi Ando Tags: RESEARCH ARTICLE Source Type: research

Assessment of salivary cadmium levels and breast density in the Marin Women's Study
ConclusionSalivary Cd is a viable quantification source in large epidemiologic studies. Association analyses between Cd levels and breast density may provide additional information for breast cancer risk assessment, risk reduction plans, and future research directions. Further work is needed to demonstrate a more robust testing protocol before the extent of its usefulness can be established. (Source: Cancer Medicine)
Source: Cancer Medicine - February 1, 2024 Category: Cancer & Oncology Authors: Michaela F. George, Shayne Paff, Jenyse Rojo, Mark Powell, Christopher Benz, Karl Pope, Karla Kerlikowske, John Shepard, Matthew Willis, Rochelle Ereman, LeeAnn Prebil Tags: RESEARCH ARTICLE Source Type: research

Anti ‐tumorigenic effects of naive and TLR4‐primed adipose‐derived mesenchymal stem cells on pancreatic ductal adenocarcinoma cells
ConclusionsThese findings underscore the significance of both the naive state and different inflammatory phenotypes of MSCs in the microenvironment and represent a pivotal step toward the development of novel therapeutic approaches for pancreatic cancer. Understanding the intricate interactions between MSCs and cancer cells may open new avenues for targeted interventions in cancer therapy. (Source: Cancer Medicine)
Source: Cancer Medicine - February 1, 2024 Category: Cancer & Oncology Authors: Demet Ka çaroğlu, Seher Yaylacı, Nilgun Gurbuz Tags: RESEARCH ARTICLE Source Type: research

Comparison of percutaneous ablation and hepatectomy for liver metastasis: A single center retrospective study
ConclusionsPercutaneous thermal ablation was performed for many cancer types than hepatectomy. It is performed in elderly patients. We suggested that ablation for colorectal liver metastasis sized ≤2 cm is a suitable indication. (Source: Cancer Medicine)
Source: Cancer Medicine - February 1, 2024 Category: Cancer & Oncology Authors: Seiichi Tawara, Tetsuro Miyazaki, Ryosuke Kiyota, Yuki Maegawa, Takeshi Shimizu, Takuo Yamai, Shoichiro Kawai, Takuya Inoue, Hisateru Komatsu, Akira Tomokuni, Masaaki Motoori, Takayuki Yakushijin Tags: RESEARCH ARTICLE Source Type: research

Cancer and the family: Variations by sex and race/ethnicity
ConclusionThere are considerable differences by sex and race/ethnicity in the characteristics of cancer survivors with minor children. Clinicians should make consideration of family circumstances a routine part of their history. Doing so will help to identify potential sources of support and responsibility that may affect adherence. (Source: Cancer Medicine)
Source: Cancer Medicine - February 1, 2024 Category: Cancer & Oncology Authors: Charlotte Asiedu, Nicole S. McKinney, Alliric I. Willis, Frances M. Lewis, Shannon Virtue, Adam Davey Tags: RESEARCH ARTICLE Source Type: research

Gemcitabine ‐based conditioning compared to BEAM/BEAC conditioning prior to autologous stem cell transplantation for non‐Hodgkin lymphoma: No difference in outcomes
ConclusionsThe GBM/GBC regimen is effective and well-tolerated, offering outcomes that are highly comparable to those in NHL patients conditioned with BEAM/BEAC, as demonstrated in a prognostically matched cohort. (Source: Cancer Medicine)
Source: Cancer Medicine - February 1, 2024 Category: Cancer & Oncology Authors: Huimin Liu, Hesong Zou, Dandan Shan, Wei Liu, Wenyang Huang, Weiwei Sui, Shuhui Deng, Tingyu Wang, Rui Lv, Mingwei Fu, Yan Xu, Shuhua Yi, Gang An, Yaozhong Zhao, Lugui Qiu, Dehui Zou Tags: RESEARCH ARTICLE Source Type: research

Understanding communication between patients and healthcare professionals regarding comprehensive biomarker testing in precision oncology: A scoping review
ConclusionsPatient education by knowledgeable and confident HCPs, information management and a caring patient-HCP relationship communicating continuity of care regardless of cBT results are crucial to empower patients and shared decision-making in precision oncology. More data on the process and structure of cBT-related communication, distinction between and characterization of different timepoints of patient-HCP interactions are needed. (Source: Cancer Medicine)
Source: Cancer Medicine - February 1, 2024 Category: Cancer & Oncology Authors: Theresia Pichler, Friederike Mumm, Navdeep Dehar, Erin Dickman, Celia D íez de Los Ríos de la Serna, Andreas Dinkel, Kathrin Heinrich, Merel Hennink, Anndra D. Parviainen, Vincent Raske, Nicole Wicki, Amy C. Moore Tags: REVIEW Source Type: research

Issue Information
(Source: Cancer Medicine)
Source: Cancer Medicine - January 31, 2024 Category: Cancer & Oncology Tags: ISSUE INFORMATION Source Type: research

Exploring the factors affecting the occurrence of postoperative MVI and the prognosis of hepatocellular carcinoma patients treated with hepatectomy: A multicenter retrospective study
ConclusionsMVI was found to be substantially linked with four subgroups of HCC patients with hepatocirrhosis, positive AFP, tumor diameter>50  mm, and LMR ≤3.4, and the prognosis of MVI-positive patients in all four subgroups tended to be worse. (Source: Cancer Medicine)
Source: Cancer Medicine - January 30, 2024 Category: Cancer & Oncology Authors: Jilin Yang, Junlin Qian, Zhao Wu, Wenjian Zhang, Zexin Yin, Wei Shen, Kun He, Yongzhu He, Liping Liu Tags: RESEARCH ARTICLE Source Type: research

Predicting survival in patients with buccal cancer: A study based on SEER database and external validation in China
ConclusionsThe nomograms developed with great performance predicted 1-, 3-, and 5-year OS and CSS of BMC patients. Use of the nomograms in clinical practices shall bring significant benefits to BMC patients. (Source: Cancer Medicine)
Source: Cancer Medicine - January 29, 2024 Category: Cancer & Oncology Authors: Yongmei Tan, Guoxing Huang, Jintao Hu, Shaoping Zhao, Yanyan Li, Zhihui Wen, Liansheng Wang, Suling Chen, Rongxi Chen, Haotian Cao, Jinsong Li Tags: RESEARCH ARTICLE Source Type: research

Beyond 5 ‐year survival. A report from the Cooperative Osteosarcoma Study Group (COSS)
ConclusionThis benchmark analysis clearly defined risk factors for the further course of 5-year survivors from osteosarcoma. It argues for large disease-oriented databases as well as for very long follow-up periods. Novel findings will most likely require innovative statistical models to analyze such cohorts. (Source: Cancer Medicine)
Source: Cancer Medicine - January 29, 2024 Category: Cancer & Oncology Authors: Julia S. Fernandes, Claudia Blattmann, Stefanie Hecker ‐Nolting, Leo Kager, Matthias Kevric, Vanessa Mettmann, Benjamin Sorg, Marc Fernandes, Stefan S. Bielack Tags: RESEARCH ARTICLE Source Type: research

LGBTQ+ inequity in crowdfunding cancer costs: The influence of online reach and LGBTQ+ state policy
Conclusions and RelevanceOur findings revealed LGBTQ+ inequity in cancer-related crowdfunding, suggesting that LGBTQ+ cancer survivors may be less able to address financial burden via crowdfunding in comparison to non-LGBTQ+ cancer survivors —potentially widening existing economic inequities. (Source: Cancer Medicine)
Source: Cancer Medicine - January 26, 2024 Category: Cancer & Oncology Authors: Austin R. Waters, Caleb W. Easterly, Cindy Turner, Lauren Ghazal, Ida Tovar, Megan Mulvaney, Matt Poquadeck, Stephen A. Rains, Kristin G. Cloyes, Anne C. Kirchhoff, Erin E. Kent, Echo L. Warner Tags: RESEARCH ARTICLE Source Type: research

Analysis of translesion polymerases in colorectal cancer cells following cetuximab treatment: A network perspective
ConclusionWe found that translesion polymerases are co-regulated with DNA mismatch repair and cell cycle-associated factors. We did not, however, identified any networks specific to cetuximab treatment indicating that the response to EGFR inhibitors relates to a general stress response mechanism. (Source: Cancer Medicine)
Source: Cancer Medicine - January 25, 2024 Category: Cancer & Oncology Authors: Anubrata Das, Georgios V. Gkoutos, Animesh Acharjee Tags: RESEARCH ARTICLE Source Type: research

The incremental healthcare cost associated with cancer in Belgium: A registry ‐based data analysis
ConclusionsIn our study, the direct attributable cost of the most prevalent cancer sites in Belgium was estimated to provide useful guidance for cost containment policies. Many of these cancers could be prevented by tackling risk factors such as smoking, obesity, and environmental stressors. (Source: Cancer Medicine)
Source: Cancer Medicine - January 25, 2024 Category: Cancer & Oncology Authors: Vanessa Gorasso, Stefanie Vandevijvere, Johan Van  der Heyden, Ingrid Pelgrims, Henk Hilderink, Wilma Nusselder, Claire Demoury, Masja Schmidt, Stijn Vansteelandt, Delphine De Smedt, Brecht Devleesschauwer Tags: RESEARCH ARTICLE Source Type: research

Target volumes comparison between postoperative simulation magnetic resonance imaging and preoperative diagnostic magnetic resonance imaging for prone breast radiotherapy after breast ‐conserving surgery
ConclusionsDespite using DIR technology, the spatial correspondence of target volumes between MRIpre and MRIpost was suboptimal. Therefore, relying solely on preoperative diagnostic MRI with DIR for postoperative LC delineation is not recommended. (Source: Cancer Medicine)
Source: Cancer Medicine - January 22, 2024 Category: Cancer & Oncology Authors: Ying Jin, Changhui Zhao, Lizhen Wang, Ya Su, Dongping Shang, Fengxiang Li, Jinzhi Wang, Xijun Liu, Jianbin Li, Wei Wang Tags: RESEARCH ARTICLE Source Type: research