Survival and safety analysis of COVID ‐19 vaccine in Chinese patients with non‐small cell lung cancer
ConclusionsCOVID-19 vaccination is safe for Chinese NSCLC patients actively receiving different antitumor treatments without increasing the incidence of adverse reactions, and vaccination does not affect cancer patient survival. (Source: Cancer Medicine)
Source: Cancer Medicine - April 23, 2024 Category: Cancer & Oncology Authors: Wei Xu, Jing Zhao, Fang Luan, Zhizhao Zhang, Lei Liu, Hui Zhao, Bin Feng, Guobin Fu Tags: RESEARCH ARTICLE Source Type: research

Effectiveness and infectious complications of BCMA T ‐cell engagers in treating multiple myeloma: Real‐world evidence from Sweden
ConclusionsDespite the risk of infectious complications, the prognosis of MM patients can be significantly improved with vigilant monitoring and proactive management of infections. This real-world data highlight the potential of BCMA T-cell engagers in treating MM, emphasizing the need for careful patient monitoring to mitigate infection risks. (Source: Cancer Medicine)
Source: Cancer Medicine - April 23, 2024 Category: Cancer & Oncology Authors: Katarina Uttervall, Love T ätting, Konstantinos Lemonakis, Mousa Majd, Jacob Crafoord, Mikael Olsson, Ulf‐Henrik Mellqvist, Markus Hansson, Hareth Nahi Tags: RESEARCH ARTICLE Source Type: research

PD ‐1 inhibition with retifanlimab and/or arginase inhibition with INCB001158 in Japanese patients with solid tumors: A phase I study
ConclusionRetifanlimab, INCB001158, and their combination had acceptable safety profiles. Promising retifanlimab antitumor activity warrants further investigation in Japanese patients. (Source: Cancer Medicine)
Source: Cancer Medicine - April 23, 2024 Category: Cancer & Oncology Authors: Yasutoshi Kuboki, Takafumi Koyama, Nobuaki Matsubara, Yoichi Naito, Shunsuke Kondo, Kenichi Harano, Kan Yonemori, Kiyotaka Yoh, Yuan Gu, Tetsuya Mita, Xuejun Chen, Eiji Ueda, Noboru Yamamoto, Toshihiko Doi, Toshio Shimizu Tags: RESEARCH ARTICLE Source Type: research

Flow cytometric minimal residual disease measurement accounting for cytogenetics in children with non ‐high‐risk acute lymphoblastic leukemia treated according to the ALL‐MB 2008 protocol
ConclusionOur data show that combining clinical risk factors with MFC-MRD measurement is the most useful tool for risk group stratification of children with BCP-ALL in the reduced-intensity protocols. However, this algorithm can be supplemented with cytogenetic data for part of the ImR group. (Source: Cancer Medicine)
Source: Cancer Medicine - April 23, 2024 Category: Cancer & Oncology Authors: Alexander Popov, Guenter Henze, Grigory Tsaur, Oleg Budanov, Julia Roumiantseva, Mikhail Belevtsev, Tatiana Verzhbitskaya, Liudmila Movchan, Svetlana Lagoyko, Liudmila Zharikova, Yulia Olshanskaya, Tatiana Riger, Alena Valochnik, Natalia Miak Tags: RESEARCH ARTICLE Source Type: research

Survival trends for left and right sided colon cancer using population ‐based SEER database: A forty‐five‐year analysis from 1975 to 2019
ConclusionLSCC was associated with superior survival compared to right sided tumors. With the adoption of modern chemotherapy regimens, prognosis between LSCC and RSCC became more divergent in favor of LSCC. Colon cancer clinical trials should strongly consider tumor sidedness as an enrollment factor. (Source: Cancer Medicine)
Source: Cancer Medicine - April 23, 2024 Category: Cancer & Oncology Authors: Mark B. Ulanja, Kwabena Oppong Asafo ‐Agyei, Vijay Neelam, Bryce D. Beutler, Daniel Antwi‐Amoabeng, Samuel B. Governor, Ganiyu A. Rahman, Francis T. Djankpa, Reginald N. Ulanja, Grace B. Nteim, Tarig Mabrouk, Millicent Amankwah, Olatunji B Tags: RESEARCH ARTICLE Source Type: research

Effects of resistance training on sleep quality and disorders among individuals diagnosed with cancer: A systematic review and meta ‐analysis of randomized controlled trials
ConclusionRT interventions of 60  minutes per session, performed 2–3 times a week for 12 weeks, with exercise intensity ranging from 60% to 80% of one-repetition maximum can be administered to cancer survivors, aiming to improve sleep outcomes. (Source: Cancer Medicine)
Source: Cancer Medicine - April 23, 2024 Category: Cancer & Oncology Authors: Dora Maric, Salvatore Ficarra, Luca Di  Bartolo, Carlo Rossi, Zoi Asimakopoulou, Apostolos Vantarakis, Ana Carbonell‐Baeza, David Jiménez‐Pavón, Beatriz Gomes, Paula Tavares, Rebecca Baxter, Susanna Pusa, Petra Thaller, Sofia Papakonst Tags: REVIEW Source Type: research

Adaptive radiotherapy for head and neck cancer: Pitfalls and possibilities from the radiation oncologist's point of view
ConclusionAlthough based on mainly non-randomized and retrospective trials, there is accumulating evidence that ART has the potential to reduce toxicity and improve quality of life and tumor control in HNC patients treated with RT. However, several questions remain regarding accurate patient selection, the ideal frequency and timing of replanning, and the appropriate way for image registration and dose calculation. Well-designed randomized prospective trials, with a predetermined protocol for both image registration and dose summation, are urgently needed to further investigate the dosimetric and clinical benefits of ART. ...
Source: Cancer Medicine - April 23, 2024 Category: Cancer & Oncology Authors: Sandra Nuyts, Heleen Bollen, Avrahram Eisbruch, Primoz Strojan, William M. Mendenhall, Sweet Ping Ng, Alfio Ferlito Tags: REVIEW Source Type: research

Incidence and prevalence of musculoskeletal health conditions in survivors of childhood and adolescent cancers: A report from the Swiss childhood cancer survivor study
ConclusionMSHCs are prevalent in survivors, the risk is increasing in younger survivor cohorts, and MSHCs usually occur in multimorbid survivors. Strengthening of rehabilitation services and appropriate referrals are needed to mitigate the effects of the cancer and cancer treatment. (Source: Cancer Medicine)
Source: Cancer Medicine - April 23, 2024 Category: Cancer & Oncology Authors: Salome Christen, Katharina Roser, Luzius Mader, Maria Otth, Katrin Scheinemann, Grit Sommer, Claudia Kuehni, Gisela Michel Tags: RESEARCH ARTICLE Source Type: research

Disparities in incidence and survival for patients with Ewing sarcoma in Florida
ConclusionsFlorida Hispanic males have a higher-than-expected incidence of osseous ES compared to the US. Hispanics of both sexes show remarkably worse survival for nonmetastatic disease compared to NHW. This disparity is likely multifactorial and requires further in-depth studies. (Source: Cancer Medicine)
Source: Cancer Medicine - April 23, 2024 Category: Cancer & Oncology Authors: Aditi Dhir, Rachna Rahul, Qinran Liu, Dan Pham, Rachel Kronenfeld, Tulay Koru ‐Sengul, Paulo S. Pinheiro Tags: RESEARCH ARTICLE Source Type: research

Metabolite signature of human malignant thyroid tissue: A systematic review and meta ‐analysis
ConclusionIt appears that the field of TC metabolomics will experience notable advancement, leading to the discovery of trustworthy diagnostic and prognostic biomarkers. (Source: Cancer Medicine)
Source: Cancer Medicine - April 22, 2024 Category: Cancer & Oncology Authors: S. Adeleh Razavi, Babak Khorsand, Pouya Salehipour, Mehdi Hedayati Tags: REVIEW Source Type: research

Review of patient ‐reported outcomes (PROs) and non‐PROs in randomized controlled trials addressing head/neck cancers
ConclusionsThere has been a growth in the types of PROs in more recent years, and they were more frequently reported in RCTs. However, head/neck cancer trials with a combination of PROs and non-PROs were the most prevalent. (Source: Cancer Medicine)
Source: Cancer Medicine - April 22, 2024 Category: Cancer & Oncology Authors: Michelle Gode, Clovis Mariano Faggion Jr Tags: REVIEW Source Type: research

Trends in colorectal cancer screening compliance and incidence among 60 ‐ to 74‐year‐olds in China
ConclusionThis study reported several risk factors associated with the screening behaviors for CRC. Patterns and trends in CRC, AA, ACN, and CN compliance and detection rates correlate with risk factors. (Source: Cancer Medicine)
Source: Cancer Medicine - April 18, 2024 Category: Cancer & Oncology Authors: Mingqing Zhang, Yongdan Zhang, Lu Guo, Lizhong Zhao, Haoren Jing, Xiao Yang, Wen Zhang, Yong Zhang, Zhenguo Nie, Siwei Zhu, Shiwu Zhang, Xipeng Zhang Tags: RESEARCH ARTICLE Source Type: research

Long noncoding RNA small nucleolar RNA host genes as prognostic molecular biomarkers in hepatocellular carcinoma: A meta ‐analysis
ConclusionsIn conclusion, upregulation of SNHGs expression correlates with shorter OS, RFS, DFS, tumor size and numbers, histologic grade, lymphatic metastasis, vein invasion, tumor stage, PVTT, and AFP level, suggesting that SNHGs may serve as prognostic biomarkers in HCC. (Source: Cancer Medicine)
Source: Cancer Medicine - April 18, 2024 Category: Cancer & Oncology Authors: Meng Huang, Zhiwen Zhao, Lihua Yang Tags: REVIEW Source Type: research

Current treatment and novel insights regarding ROS1 ‐targeted therapy in malignant tumors
ConclusionsFurther research on next-generation TKIs regarding the localization of ROS1 and its fusion partners, binding sites for targeted drugs, and coadministration with other drugs is required. The correlation between TKIs and chemotherapy or immunotherapy in clinical practice requires further study. (Source: Cancer Medicine)
Source: Cancer Medicine - April 17, 2024 Category: Cancer & Oncology Authors: Shizhe Li, He Zhang, Ting Chen, Xiaowen Zhang, Guanning Shang Tags: REVIEW Source Type: research

Understanding the financial cost of cancer clinical trial participation
ConclusionCancer clinical trial-related financial hardship, most often stemming from travel expenses, affected almost half of trial-enrolled patients. Interventions are needed to reduce adverse financial participation effects and potentially improve cancer clinical trial participation. (Source: Cancer Medicine)
Source: Cancer Medicine - April 17, 2024 Category: Cancer & Oncology Authors: Courtney P. Williams, Luqin Deng, Nicole E. Caston, Kathleen Gallagher, Rebekah Angove, Maria Pisu, Andres Azuero, Rebecca Arend, Gabrielle B. Rocque Tags: RESEARCH ARTICLE Source Type: research