Effect of ultrasound-guided stellate ganglion block on cerebral oxygen metabolism and S100B protein during carotid endarterectomy
CONCLUSION: SGB before CEA effectively suppresses the stress response, maintains intraoperative hemodynamic stability, improves brain tissue oxygen supply, and demonstrates a neuroprotective effect.PMID:38586110 | PMC:PMC10994798 | DOI:10.62347/RXRN7802 (Source: American Journal of Translational Research)
Source: American Journal of Translational Research - April 8, 2024 Category: Research Authors: Fen Yang Yulong Du Chen Yuan Li Han Yue Zhao Yang Xie Wenyong Peng Source Type: research

Efficacy of the combination of BRII-196/BRII-198 in the treatment of COVID-19 vaccine breakthrough infections
CONCLUSIONS: The initial levels of SARS-CoV-2 IgG antibody and lymphocytes in fully vaccinated patients with breakthrough infections are inversely correlated with the severity of the disease. Early treatment with BRII-196/BRII-198 can shorten NA negative conversion time in severe COVID-19 patients and increase in vivo neutralizing antibody levels post-conversion, providing lasting protection. However, BRII-196/BRII-198 does not influence lymphocyte count recovery in patients with either ordinary and/or severe COVID-19.PMID:38586111 | PMC:PMC10994788 | DOI:10.62347/NDGV1857 (Source: American Journal of Translational Research)
Source: American Journal of Translational Research - April 8, 2024 Category: Research Authors: Xiao-Ling Guo Kun Wang Jie Jin Li-Li Dai Source Type: research

Efficacy of levetiracetam combined with oxcarbazepine in the treatment of adults with temporal lobe epilepsy and its impact on memory and cognitive function
CONCLUSION: Levetiracetam combined with oxcarbazepine effectively improves cognitive dysfunction in adults with temporal lobe epilepsy, with superior efficacy to levetiracetam alone, and good safety.PMID:38586112 | PMC:PMC10994801 | DOI:10.62347/KNTE8578 (Source: American Journal of Translational Research)
Source: American Journal of Translational Research - April 8, 2024 Category: Research Authors: Zhangxia Li Xiongfei Zhao Guoxun Zhang Cong Xi Liying Yang Source Type: research

Obesity attenuates the beneficial effect of an intrauterine infusion of autologous platelet-rich plasma during in vitro fertilization
CONCLUSION: PRP improved embryo implantation and clinical pregnancy rates; however, these beneficial effects were attenuated by obesity. PRP presumptively promoted a change in the uterine environment to mimic the normal findings associated with normal-weight women.PMID:38586113 | PMC:PMC10994790 | DOI:10.62347/RDXA5841 (Source: American Journal of Translational Research)
Source: American Journal of Translational Research - April 8, 2024 Category: Research Authors: Dinorah Hern ández-Melchor H éctor Carrillo Alfredo Mart ín Rivera Leonardo M Porchia Priscila M Bartolo-G ómez Jazm ín Martínez Am érica Padilla-Viveros Martha Elba Gonzalez-Mej ía Esther L ópez-Bayghen Source Type: research

Human immunoglobulin in combination with antimicrobial agents enhances the treatment efficacy and reduces inflammatory response in children with severe pneumonia
CONCLUSION: The combination of human immunoglobulin and antibiotics for the treatment of pediatric severe pneumonia is beneficial, because it improves efficacy, boosts the immune system, and reduces inflammation.PMID:38586114 | PMC:PMC10994785 | DOI:10.62347/KQUW5330 (Source: American Journal of Translational Research)
Source: American Journal of Translational Research - April 8, 2024 Category: Research Authors: Wenli Zhang Yue Jin Source Type: research

Decoding the DSCC1 gene as a pan-cancer biomarker in human cancers via comprehensive multi-omics analyses
CONCLUSION: Overall, this study provides comprehensive insights into the pivotal role of DSCC1 in KIRP, LIHC, and LUAD initiation, progression, and therapeutic responsiveness, laying the foundation for further investigations and personalized treatment strategies.PMID:38586115 | PMC:PMC10994803 | DOI:10.62347/YORR3755 (Source: American Journal of Translational Research)
Source: American Journal of Translational Research - April 8, 2024 Category: Research Authors: Jingru Wang Sana Fatima Gilani Nazia Noor Muhammad Rashid Ahmed Mehmooda Munazir Ayesha Zubair Rizwana Sultan Mostafa A Abdel-Maksoud Ibrahim A Saleh Naser Zomot Ahmad S Kodous Shebl Salah Ibrahim Mohamed A El-Tayeb Mohammed Aufy Mohamed Y Zaky Syed Sairu Source Type: research

Exploration of the molecular mechanism guiding Xinfeng capsule regulatory mechanism for rheumatoid arthritis inflammation
CONCLUSIONS: XFC could effectively improve the clinical inflammatory indexes of RA. The active ingredients of XFC improved the inflammatory state of RA by regulating the TLR-signaling pathway.PMID:38586085 | PMC:PMC10994809 | DOI:10.62347/TPOQ4910 (Source: American Journal of Translational Research)
Source: American Journal of Translational Research - April 8, 2024 Category: Research Authors: Ziheng Zhu Lei Wan Source Type: research

Effects of the novel sodium-dependent phosphate cotransporter 2b inhibitor DZ1462 on hyperphosphatemia in chronic kidney disease
CONCLUSIONS: This study revealed that a GI-restricted NPT2b inhibitor DZ1462 potently inhibits NPT2b in vitro and blocks intestinal phosphate uptake in multiple animal models with potential to reduce various cardiovascular events in CKD models. Therefore, DZ1462 may be useful to treat renal disease patients who have shown an unsatisfactory response to phosphate binders.PMID:38586086 | PMC:PMC10994808 | DOI:10.62347/UGTW5471 (Source: American Journal of Translational Research)
Source: American Journal of Translational Research - April 8, 2024 Category: Research Authors: Xiao Lu Ling-Zhi Yu Qiu-Li Guo Lin Zhang Shan-Xiang Jiang Source Type: research

Effects of multidisciplinary team continuous care model on psychological behavior and quality of life in children with β-thalassemia major
CONCLUSION: The MDT continuous care model can effectively promote mental health in children with β-TM, improve their quality of life, medical satisfaction, ameliorate the degree of anemia in children, reduce the incidence of complications and improve the prognosis; thus, it is worthy of wide clinical application.PMID:38586087 | PMC:PMC10994799 | DOI:10.62347/OBWD7382 (Source: American Journal of Translational Research)
Source: American Journal of Translational Research - April 8, 2024 Category: Research Authors: Xiuping Huang Jian Lu Rongxian Huang Qingmei Lu Yanni Luo Xiaoxiao Huang Liqiao An Yuke Chen Source Type: research

Electroacupuncture protects the intestinal mucosal barrier in diarrhea-predominant Irritable Bowel Syndrome rats by regulating the MCs/Tryptase/PAR-2/MLCK pathway
CONCLUSION: EA has a good therapeutic effect on IBS-D rats. Regulating the MCs/Tryptase/PAR-2/MLCK pathway may be a mechanism to protect the intestinal mucosal barrier.PMID:38586088 | PMC:PMC10994796 | DOI:10.62347/VZJL1218 (Source: American Journal of Translational Research)
Source: American Journal of Translational Research - April 8, 2024 Category: Research Authors: Xiao-Yu Han Xiao-Ge Song Wen-Li Ma Ming Fang Jing-Wei Zhu Jing-Ru Ruan Kui-Wu Li Ling Zou Lu-Min Liao Xiao-Min Li Zi-Ye Wang Yu-Cheng Fang Hao-Ran Chu Source Type: research

Artificial intelligence in cardiology: a bibliometric study
CONCLUSIONS: Enhancing cooperation between different countries and institutions is a critical step in leading to breakthroughs in the application of AI in cardiology. It is foreseeable that the application of machine learning and deep learning in various areas of cardiology will be a research priority in the coming years.PMID:38586089 | PMC:PMC10994793 | DOI:10.62347/HSFE6936 (Source: American Journal of Translational Research)
Source: American Journal of Translational Research - April 8, 2024 Category: Research Authors: Yalan Zhang Jingwen Xie Enlong Fu Wan Cai Wentan Xu Source Type: research

Thorough examination of the potential biological implications of the cuproptosis-related gene LIPT2 in the prognosis and immunotherapy in pan-cancer
CONCLUSION: Overall, our study highlights LIPT2 as a versatile player in cancer, influencing diverse aspects from molecular processes to clinical outcomes across different cancer types.PMID:38586090 | PMC:PMC10994786 | DOI:10.62347/QNNE5428 (Source: American Journal of Translational Research)
Source: American Journal of Translational Research - April 8, 2024 Category: Research Authors: Mi Luo Abdul Rehman Soha Haque Saba Izhar Fauzia Perveen Muhammad Haris Mostafa A Abdel-Maksoud Ibrahim A Saleh Naser Zomot Abdul Malik Abdulaziz Alamri Ahmad S Kodous Mohammed Aufy Mohamed Y Zaky Muhammad Zaeem Yasir Hameed Junwei Li Source Type: research

Serum monocyte chemotactic protein 1 and soluble mannose receptor aid predictive diagnosis of pediatric sepsis
CONCLUSIONS: Serum sMR and MCP-1 levels can help predict the diagnosis of pediatric sepsis.PMID:38586091 | PMC:PMC10994783 | DOI:10.62347/FZMM3162 (Source: American Journal of Translational Research)
Source: American Journal of Translational Research - April 8, 2024 Category: Research Authors: Danyang Song Xiurong Zheng Source Type: research

Significant enhancement of swallowing function and oral hygiene following multidisciplinary team nursing in tongue cancer patients after radical resection
CONCLUSION: MDT nursing have a positive impact on oral hygiene as well as the swallowing function of patients after radical resection of TC, and MDT is a protective factor for swallowing function in the patients after radical resection.PMID:38586092 | PMC:PMC10994800 | DOI:10.62347/TQFJ8242 (Source: American Journal of Translational Research)
Source: American Journal of Translational Research - April 8, 2024 Category: Research Authors: Lan Xiao Xie Yu Miao He Yi Men Source Type: research

Changes in TNF- α, IL-33, and MIP-1α before and after artificial liver support treatment and their prognostic value
CONCLUSION: ALST can significantly reduce TNF-α, IL-33, and MIP-1α levels in patients with ACLF, and postoperative TNF-α, IL-33, and MIP-1α levels have a high predictive value for patients' prognosis.PMID:38586093 | PMC:PMC10994792 | DOI:10.62347/CBKR4894 (Source: American Journal of Translational Research)
Source: American Journal of Translational Research - April 8, 2024 Category: Research Authors: Jian Zhou Zhengmao Yang Xiaoqing Yang Zhaoxun Wang Source Type: research