Control of N ‐Heterocyclic Carbene Catalyzed Reactions of Enals: Asymmetric Synthesis of Oxindole‐γ‐Amino Acid Derivatives
AngewchemControl of N ‐Heterocyclic Carbene Catalyzed Reactions of Enals: Asymmetric Synthesis of Oxindole‐γ‐Amino Acid Derivatives: A strategy to control the switch between a non ‐cycloaddition reaction and a cycloaddition reaction of enals, using N‐heterocyclic carbene (NHC) catalyisis, has been developed. The new scalable protocol... (Source: Organometallic Current)
Source: Organometallic Current - December 8, 2017 Category: Chemistry Tags: Asymmetric Heterocycles organocatalysis Source Type: blogs

A Versatile Route to Unstable Diazo Compounds via Oxadiazolines and their Use in Aryl –Alkyl Cross‐Coupling Reactions
AngewchemA Versatile Route to Unstable Diazo Compounds via Oxadiazolines and their Use in Aryl –Alkyl Cross‐Coupling Reactions: Coupling of readily available boronic acids and diazo compounds has emerged recently as a powerful metal ‐free carbon–carbon bond forming method. However, the difficulty in forming the unstable diazo compound... (Source: Organometallic Current)
Source: Organometallic Current - December 8, 2017 Category: Chemistry Tags: Cross Coupling Photochemical Rxn Source Type: blogs

Divergent Total Syntheses of ( −)‐Daphnilongeranin B and (−)‐Daphenylline
AngewchemDivergent Total Syntheses of ( −)‐Daphnilongeranin B and (−)‐Daphenylline: ( −)‐Daphnilongeranin B and (−)‐daphenylline are two hexacyclic Daphniphyllum alkaloids, each containing a complex cagelike backbone. Described herein are the first asymmetric total synthesis of (−)‐daphnilongeranin B... (Source: Organometallic Current)
Source: Organometallic Current - December 8, 2017 Category: Chemistry Tags: Natural products Total synthesis Source Type: blogs

1,1 ‐Hydroboration and a Borane Adduct of Diphenyldiazomethane: A Potential Prelude to FLP‐N2 Chemistry
Angewchem1,1 ‐Hydroboration and a Borane Adduct of Diphenyldiazomethane: A Potential Prelude to FLP‐N2 Chemistry: Diphenyldiazomethane reacts with HB(C6F5)2 and B(C6F5)3, resulting in 1,1 ‐hydroboration and adduct formation, respectively. The hydroboration proceeds via a concerted reaction involving initial formation... (Source: Organometallic Current)
Source: Organometallic Current - December 8, 2017 Category: Chemistry Tags: Hydroboration Source Type: blogs

Site ‐Selective O‐Arylation of Glycosides
AngewchemSite ‐Selective O‐Arylation of Glycosides: Direct and site ‐selective O‐arylation of carbohydrates has been a challenge in synthesis. Herein we report a method based on copper‐catalyzed O‐arylation to address this challenge. Proper choice of the... (Source: Organometallic Current)
Source: Organometallic Current - December 8, 2017 Category: Chemistry Tags: Arylation Carbohydrates Cu catalyzed Source Type: blogs

Iron(II) ‐Catalyzed Direct Synthesis of NH Sulfoximines from Sulfoxides
AngewchemIron(II) ‐Catalyzed Direct Synthesis of NH Sulfoximines from Sulfoxides: Free NH ‐sulfoximines were directly prepared from sulfoxides through iron catalysis by applying a readily available, shelf‐stable hydroxylamine triflic acid salt. No additional oxidant is needed, and the... (Source: Organometallic Current)
Source: Organometallic Current - December 8, 2017 Category: Chemistry Tags: Fe catalyzed Source Type: blogs

Palladium ‐Catalyzed Intermolecular Acylation of Aryl Diazoesters with ortho‐Bromobenzaldehydes
AngewchemPalladium ‐Catalyzed Intermolecular Acylation of Aryl Diazoesters with ortho‐Bromobenzaldehydes: In this work, we describe a palladium ‐catalyzed intermolecular O acylation of α‐diazoesters with ortho‐bromobenzaldehydes. The C(sp2)−H bond activation of the aldehyde is enabled by migratory insertion... (Source: Organometallic Current)
Source: Organometallic Current - December 8, 2017 Category: Chemistry Tags: Acylation Pd Catalyzed Source Type: blogs

Controlled Radical Polymerization of Ethylene Using Organotellurium Compounds
AngewchemControlled Radical Polymerization of Ethylene Using Organotellurium Compounds: The first successfully controlled radical polymerization (CRP) of ethylene is reported using several organotellurium chain ‐transfer agents (CTAs) under mild conditions (70 °C, 200 bar of ethylene) within... (Source: Organometallic Current)
Source: Organometallic Current - December 8, 2017 Category: Chemistry Tags: Polymerization Source Type: blogs

Internal Peptide Late ‐Stage Diversification: Peptide‐Isosteric Triazoles for Primary and Secondary C(sp3)−H Activation
AngewchemInternal Peptide Late ‐Stage Diversification: Peptide‐Isosteric Triazoles for Primary and Secondary C(sp3)−H Activation: Secondary C(sp3) −H arylations were accomplished by palladium catalysis with triazoles as peptide bond isosteres. The unique power of this approach is highlighted by the possibility of achieving secondary... (Source: Organometallic Current)
Source: Organometallic Current - December 8, 2017 Category: Chemistry Tags: Arylation Pd Catalyzed Peptide Modification sp3 C-H Activation Source Type: blogs

Fluorinated Vinylsilanes from the Copper ‐Catalyzed Defluorosilylation of Fluoroalkene Feedstocks
AngewchemFluorinated Vinylsilanes from the Copper ‐Catalyzed Defluorosilylation of Fluoroalkene Feedstocks: Herein, a copper ‐catalyzed C−F bond defluorosilylation reaction of tetrafluoroethylene and other polyfluoroalkenes is described. Mechanistic studies, based on a series of stoichiometric reactions with... (Source: Organometallic Current)
Source: Organometallic Current - December 8, 2017 Category: Chemistry Tags: C-F Bond Activation Cu catalyzed Source Type: blogs

Aluminabenzene –Rh and −Ir Complexes: Synthesis, Structure, and Application toward Catalytic C–H Borylation
JacsAluminabenzene –Rh and −Ir Complexes: Synthesis, Structure, and Application toward Catalytic C–H Borylation: Aluminabenzene –rhodium and −iridium complexes were synthesized, in which the aluminum atom played as a proximal Lewis acidic site. Based on their structural analysis, aluminabenzene ligand could coordinate to Rh and Ir as a η5-pentadienyl ligand. (Source: Organometallic Current)
Source: Organometallic Current - December 5, 2017 Category: Chemistry Tags: Borylation Ir catalyzed Rh Catalyzed Source Type: blogs

Selective Single C(sp3) –F Bond Cleavage in Trifluoromethylarenes: Merging Visible-Light Catalysis with Lewis Acid Activation
We report here the first example of single C(sp3) –F functionalization of trifluoromethylarenes via visible-light catalysis merged with Lewis acid activation. (Source: Organometallic Current)
Source: Organometallic Current - December 5, 2017 Category: Chemistry Tags: C-F Bond Activation Lewis acid catalysis Visible light Source Type: blogs

Gram-Scale Syntheses and Conductivities of [10]Cycloparaphenylene and Its Tetraalkoxy Derivatives
: [10]Cycloparaphenylene ([10]CPP) and its tetraalkoxy derivatives were synthesized on the gram scale in 7 steps starting from 1,4-benzoquinone or 2,5-dialkoxy-1,4-benzoquinone. The key steps involve the highlycis-selective bis-addition of 4-bromo-4 ′-lithiobiphenyl to the quinones to produce a five-ring unit containing cyclohexa-1,4-diene-3,6-diol moiety, the platinum-mediated dimerization of the five-ring unit, and the H2SnCl4-mediated reductive aromatization of cyclohexadienediol. (Source: Organometallic Current)
Source: Organometallic Current - December 5, 2017 Category: Chemistry Tags: Advanced materials Source Type: blogs

Design of a Photoredox Catalyst that Enables the Direct Synthesis of Carbamate-Protected Primary Amines via Photoinduced, Copper-Catalyzed N-Alkylation Reactions of Unactivated Secondary Halides
JacsDesign of a Photoredox Catalyst that Enables the Direct Synthesis of Carbamate-Protected Primary Amines via Photoinduced, Copper-Catalyzed N-Alkylation Reactions of Unactivated Secondary Halides: Design of a Photoredox Catalyst that Enables the Direct Synthesis of Carbamate-Protected Primary Amines via Photoinduced, Copper-Catalyzed N-Alkylation Reactions of Unactivated Secondary Halides (Source: Organometallic Current)
Source: Organometallic Current - December 5, 2017 Category: Chemistry Tags: Alkylation Cu catalyzed Photoredox Catalysis Source Type: blogs

Iron-Catalyzed 1,2-Selective Hydroboration of N-Heteroarenes
JacsIron-Catalyzed 1,2-Selective Hydroboration of N-Heteroarenes: A N2-bridged diiron complex [Cp*(Ph2PC6H4S)Fe]2( μ-N2) (1) has been found to catalyze the hydroboration ofN-heteroarenes with pinacolborane, givingN-borylated 1,2-reduced products with high regioselectivity. The catalysis is initiated by coordination ofN-heteroarenes to the iron center, while the B –H bond cleavage is the rate-determining step. (Source: Organometallic Current)
Source: Organometallic Current - December 5, 2017 Category: Chemistry Tags: Fe catalyzed Hydroboration Source Type: blogs