Intramolecular Acetyl Transfer to Olefins by Catalytic C −C Bond Activation of Unstrained Ketones
AngewchemIntramolecular Acetyl Transfer to Olefins by Catalytic C −C Bond Activation of Unstrained Ketones: A rhodium ‐catalyzed intramolecular acetyl‐group transfer has been achieved through a “cut and sew” process. The challenge arises from the existence of different competitive pathways. Preliminary success... (Source: Organometallic Current)
Source: Organometallic Current - December 11, 2017 Category: Chemistry Tags: C-C bond activation Rh Catalyzed Source Type: blogs

Rhodium ‐Catalyzed Cyclization of O,ω‐Unsaturated Alkoxyamines: Formation of Oxygen‐Containing Heterocycles
AngewchemRhodium ‐Catalyzed Cyclization of O,ω‐Unsaturated Alkoxyamines: Formation of Oxygen‐Containing Heterocycles: O, ω‐Unsaturated N‐tosyl alkoxyamines undergo unexpected RhIII‐catalyzed intramolecular cyclization by oxyamination to produce oxygen‐containing heterocycles. Mechanistic studies show that an aziridine... (Source: Organometallic Current)
Source: Organometallic Current - December 11, 2017 Category: Chemistry Tags: Cyclization Rh Catalyzed Source Type: blogs

Nickel(0) ‐Catalyzed Hydroarylation of Styrenes and 1,3‐Dienes with Organoboron Compounds
AngewchemNickel(0) ‐Catalyzed Hydroarylation of Styrenes and 1,3‐Dienes with Organoboron Compounds: A Ni ‐catalyzed hydroarylation of styrenes and 1,3‐dienes with organoboron compounds has been developed. The reaction offers a highly selective approach to diarylalkanes and allylarenes under redox‐neutral... (Source: Organometallic Current)
Source: Organometallic Current - December 11, 2017 Category: Chemistry Tags: Hydroarylation Ni Catalyzed Source Type: blogs

Renewable acrylonitrile production
We present a process for renewable ACN production using 3-hydroxypropionic acid (3-HP), which can be produced microbially from sugars. The process achieves ACN molar yields exceeding 90% from ethyl 3-hydroxypropanoate (ethyl 3-HP) via dehydration and nitrilation with ammonia over an inexpensive titanium dioxide solid acid catalyst.  (Source: Organometallic Current)
Source: Organometallic Current - December 8, 2017 Category: Chemistry Tags: Ti catalyzed Source Type: blogs

Electrochemical Synthesis of Aryl Iodides by Anodic Iododesilylation
AngewchemElectrochemical Synthesis of Aryl Iodides by Anodic Iododesilylation: An electrochemical access to iodinated aromatic compounds starting from trimethylsilyl ‐substituted arenes is presented. By design of experiments, highly efficient and mild conditions were identified for... (Source: Organometallic Current)
Source: Organometallic Current - December 8, 2017 Category: Chemistry Tags: Electrochemical Halogenation Source Type: blogs

Ruthenium(II) ‐Catalyzed Synthesis of Spirobenzofuranones by a Decarbonylative Annulation Reaction
AngewchemRuthenium(II) ‐Catalyzed Synthesis of Spirobenzofuranones by a Decarbonylative Annulation Reaction: The first decarbonylative insertion of an alkyne through C −H/C−C activation of six‐membered compounds is reported. The Ru‐catalyzed reaction of 3‐hydroxy‐2‐phenyl‐chromones with alkynes works most efficiently... (Source: Organometallic Current)
Source: Organometallic Current - December 8, 2017 Category: Chemistry Tags: annulation Ru catalyzed Spirocycles Source Type: blogs

Sulfamate Esters Guide Selective Radical ‐Mediated Chlorination of Aliphatic C−H Bonds
AngewchemSulfamate Esters Guide Selective Radical ‐Mediated Chlorination of Aliphatic C−H Bonds: Masked alcohols are particularly appealing as directing groups because of the ubiquity of hydroxy groups in organic small molecules. Herein, we disclose a general strategy for aliphatic γ‐C(sp3)−H functionalization... (Source: Organometallic Current)
Source: Organometallic Current - December 8, 2017 Category: Chemistry Tags: Radical Reactions Visible light Source Type: blogs

Gram ‐Scale Synthesis of the (−)‐Sparteine Surrogate and (−)‐Sparteine
AngewchemGram ‐Scale Synthesis of the (−)‐Sparteine Surrogate and (−)‐Sparteine: An 8 ‐step, gram‐scale synthesis of the (−)‐sparteine surrogate (22 % yield, with just 3 chromatographic purifications) and a 10‐step, gram‐scale synthesis of (−)‐sparteine (31 % yield) are reported. Both... (Source: Organometallic Current)
Source: Organometallic Current - December 8, 2017 Category: Chemistry Tags: Total synthesis Source Type: blogs

Direct Dehydroxytrifluoromethoxylation of Alcohols
AngewchemDirect Dehydroxytrifluoromethoxylation of Alcohols: The first example of a direct dehydroxytrifluoromethoxylation of alcohols has been developed. This method generated an alkyl fluoroformate in  situ from alcohols, followed by nucleophilic trifluoromethoxylation... (Source: Organometallic Current)
Source: Organometallic Current - December 8, 2017 Category: Chemistry Tags: Trifluoromethylation Source Type: blogs

A Gold ‐Catalyzed Domino Cyclization Enabling Rapid Construction of Diverse Polyheterocyclic Frameworks
We report herein an efficient gold(I) ‐catalyzed post‐Ugi domino dearomatization/ipso‐cyclization/Michael sequence that enables access to libraries of diverse (hetero)arene‐annulated tricyclic heterocycles.... (Source: Organometallic Current)
Source: Organometallic Current - December 8, 2017 Category: Chemistry Tags: Gold Catalysis Polycycles Source Type: blogs

Isoindigo ‐3,4‐Difluorothiophene Polymer Acceptors Yield “All‐Polymer” Bulk‐Heterojunction Solar Cells with over 7 % Efficiency
AngewchemIsoindigo ‐3,4‐Difluorothiophene Polymer Acceptors Yield “All‐Polymer” Bulk‐Heterojunction Solar Cells with over 7 % Efficiency: Poly(isoindigo ‐alt‐3,4‐difluorothiophene) (PIID[2F]T) analogues used as “polymer acceptors” in bulk‐heterojunction (BHJ) solar cells achieve 7 % efficiency when used in conjunction with the polymer donor... (Source: Organometallic Current)
Source: Organometallic Current - December 8, 2017 Category: Chemistry Tags: Advanced materials Solar Cell Source Type: blogs

Biocatalytic Oxidative Cascade for the Conversion of Fatty Acids to α‐Ketoacids via Internal H2O2 Recycling
AngewchemBiocatalytic Oxidative Cascade for the Conversion of Fatty Acids to α‐Ketoacids via Internal H2O2 Recycling: The functionalization of bio ‐based chemicals is essential to allow valorization of natural carbon sources. An atom‐efficient biocatalytic oxidative cascade was developed for the conversion of saturated... (Source: Organometallic Current)
Source: Organometallic Current - December 8, 2017 Category: Chemistry Tags: Biocatalytic oxidation Source Type: blogs

Catalytic Dibenzocyclooctene Synthesis via Cobalt(III) –Carbene Radical and ortho‐Quinodimethane Intermediates
AngewchemCatalytic Dibenzocyclooctene Synthesis via Cobalt(III) –Carbene Radical and ortho‐Quinodimethane Intermediates: The metalloradical activation of ortho ‐benzallylaryl N‐tosyl hydrazones with [Co(TPP)] (TPP=tetraphenylporphyrin) as the catalyst enabled the controlled exploitation of the single‐electron reactivity of... (Source: Organometallic Current)
Source: Organometallic Current - December 8, 2017 Category: Chemistry Tags: Co catalyzed Radical Reactions Source Type: blogs

Atropoenantioselective Redox ‐Neutral Amination of Biaryl Compounds through Borrowing Hydrogen and Dynamic Kinetic Resolution
We report herein a novel atropoenantioselective redox ‐neutral amination of biaryl compounds triggered by a cascade of borrowing hydrogen and dynamic kinetic resolution under the cooperative catalysis of... (Source: Organometallic Current)
Source: Organometallic Current - December 8, 2017 Category: Chemistry Tags: Amination Enantioselective Kinetic resolution Source Type: blogs

Review:Complementary Strategies for Directed C(sp3) −H Functionalization: A Comparison of Transition‐Metal‐Catalyzed Activation, Hydrogen Atom Transfer, and Carbene/Nitrene Transfer
AngewchemComplementary Strategies for Directed C(sp3) −H Functionalization: A Comparison of Transition‐Metal‐Catalyzed Activation, Hydrogen Atom Transfer, and Carbene/Nitrene Transfer: The functionalization of C(sp3) −H bonds streamlines chemical synthesis by allowing the use of simple molecules and providing novel synthetic disconnections. Intensive recent efforts in the development... (Source: Organometallic Current)
Source: Organometallic Current - December 8, 2017 Category: Chemistry Tags: Reviews sp3 C-H Activation Source Type: blogs