Lipoprotein changes with renal disease

Alterations in lipid metabolism occur in 35 to 85% of people with chronic kidney disease (CKD) and are characterized by increases in low-density lipoproteins (LDL), very low-density lipoproteins (VLDL), and their oxidized derivatives, as well as by decreased high-density lipoproteins (HDL). These changes are considered largely responsible for associated cardiovascular disease. Lipoprotein changes also are thought to be key contributors to the oxidative injury and inflammation in the kidney. The incidence, severity, and consequences of altered lipid metabolism in dogs with CKD are unknown.
Source: Advances in Small Animal Medicine and Surgery - Category: Veterinary Research Tags: Neurology/Urology Source Type: research