Sensing and Responding to Cytosolic Viruses Invasions: an Orchestra of Kaleidoscopic Ubiquitinations

Most proteins are covalently modified by certain small chemical group(s) after translation. This process, termed post-translational modification (PTM), broadens the function of target proteins temporally and spatially, thereby fine-tuning the corresponding biological processes. The post-translational modification groups include not only small molecules (phosphates, methyl/acetyl groups or carbohydrates) but also peptides such as ubiquitin and ubiquitin-like proteins [1].

Source: Cytokine and Growth Factor Reviews - April 1, 2015 Category: Molecular Biology Authors: Xing Liu, Qiang Wang, Youdong Pan, Chen Wang Tags: Survey Source Type: research