Thrombophilic Mutations as Risk Factor for Retinal Vein Occlusion: A Case-Control Study
Conclusions:
In our study, the FII G20210A and the MTHFR C677T mutations resulted significantly higher in patients than in controls; in contrast, thrombophilic mutation of FV, ACE, and PAI-1 genes was not statistically correlated with RVO. In spite of having found an association between some thrombophilic mutations and RVO, more studies with a major number of patients are necessary to determine the final role of these gene variants.
Source: Clinical and Applied Thrombosis/Hemostasis - Category: Hematology Authors: Russo, P. D., Damante, G., Pasca, S., Turello, M., Barillari, G. Tags: Original Articles Source Type: research