Statistical issues in the comparison of quantitative imaging biomarker algorithms using pulmonary nodule volume as an example

This study allows a direct assessment of six algorithms’ performance for measuring tumor change. With these three examples we compare and contrast study designs and performance metrics, and we illustrate the advantages and limitations of various common statistical methods for quantitative imaging biomarker studies.

Source: Statistical Methods in Medical Research - March 24, 2015 Category: Statistics Authors: Obuchowski, N. A., Barnhart, H. X., Buckler, A. J., Pennello, G., Wang, X.-F., Kalpathy-Cramer, J., Kim, H. J., Reeves, A. P., for the Case Example Working Group Tags: Articles Source Type: research