Insulin Treatment Prevents the Increase in D-Serine in Hippocampal CA1 Area of Diabetic Rats

Conclusions:
These results suggest that insulin treatment has a potent protection effect on CA1-LTP, spatial learning and memory ability of the diabetic rats in vivo. Furthermore, insulin may take effect by inhibiting the overactivation of N-methyl-d-aspartate receptors, which play a critical role in neurotoxicity.

Source: American Journal of Alzheimer's Disease and Other Dementias - March 23, 2015 Category: Geriatrics Authors: Yang, J., Song, Y., Wang, H., Liu, C., Li, Z., Liu, Y., Kong, Y. Tags: Current Topics in Research Source Type: research