Cancers, Vol. 14, Pages 569: Adrenal Mass Characterization in the Era of Quantitative Imaging: State of the Art

Cancers, Vol. 14, Pages 569: Adrenal Mass Characterization in the Era of Quantitative Imaging: State of the Art Cancers doi: 10.3390/cancers14030569 Authors: Maxime Barat Anne-Ségolène Cottereau Sébastien Gaujoux Florence Tenenbaum Mathilde Sibony Jérôme Bertherat Rossella Libé Martin Gaillard Anne Jouinot Guillaume Assié Christine Hoeffel Philippe Soyer Anthony Dohan Detection and characterization of adrenal lesions have evolved during the past two decades. Although the role of imaging in adrenal lesions associated with hormonal secretion is usually straightforward, characterization of non-functioning adrenal lesions may be challenging to confidently identify those that need to be resected. Although many adrenal lesions can be readily diagnosed when they display typical imaging features, the diagnosis may be challenging for atypical lesions. Computed tomography (CT) remains the cornerstone of adrenal imaging, but other morphological or functional modalities can be used in combination to reach a diagnosis and avoid useless biopsy or surgery. Early- and delayed-phase contrast-enhanced CT images are essential for diagnosing lipid-poor adenoma. Ongoing studies are evaluating the capabilities of dual-energy CT to provide valid virtual non-contrast attenuation and iodine density measurements from contrast-enhanced examinations. Adrenal lesions with attenuation values between 10 and 30 Hounsfield units (HU) on unenhanced CT can be characterize...
Source: Cancers - Category: Cancer & Oncology Authors: Tags: Review Source Type: research