Relationship between bone density and bone metabolism in adolescent idiopathic scoliosis

This study assessed bone mineral density and bone metabolism in AIS patients using the bone metabolism markers, BAP and TRAP5b. The subjects were 49 consecutive adolescent AIS patients seen at our institutes between March 2012 and September 2013.Sixty-five percent of AIS patients had osteopenia or osteoporosis and 59% of AIS patients had high values for TRAP5b. The AIS patients with high values of TRAP5b had lower Z scores than those with normal values of TRAP5b. Higher rates of bone resorption are associated with low bone density in AIS patients.

Source: Scoliosis - March 19, 2015 Category: Orthopaedics Authors: Ko IshidaYoichi AotaNaoto MitsugiMotonori KonoTakayuki HigashiTakuya KawaiKatsutaka YamadaTakanori NiimuraKanichiro KanekoYohei ItoTomoyuki KatsuhataTomoyuki Saito Source Type: research