A prognostic approach on a case of pediatric Philadelphia chromosome ‐positive acute lymphoblastic leukemia with monosomy‐7

Our case report highlights the occurrence of monosomy-7 as a distinct marker of poor outcome in children with Philadelphia-positive ALL. AbstractIn this work, we present the first case of a Ph-positive ALL Moroccan girl witht(9;22)(q34;q11) and monosomy-7. She was diagnosed with Ph-positive ALL based on bone marrow examination, immunophenotyping, and cytogenetic analysis. She relapsed after treatment with the persistence of the Ph chromosome and the appearance of a monosomy-7.
Source: Clinical Case Reports - Category: General Medicine Authors: Tags: CASE REPORT Source Type: research