Defining the Patchy Landscape of Esophageal Eosinophilia in Children with Eosinophilic Esophagitis

Eosinophilic Esophagitis (EoE) is a patchy disease of the esophagus with significant variability in intra-epithelial eosinophilia. Three biopsies each from distal and proximal esophagus are recommended for identification of active EoE. Recent work suggests 3 biopsy sites is more optimal. We sought to evaluate 2-site vs. 3-site esophageal biopsy combinations for utility to identify active EoE.

Source: Clinical Gastroenterology and Hepatology - December 22, 2021 Category: Gastroenterology Authors: Joshua B. Wechsler, Scott M. Bolton, Elizabeth Gray, Kwang-Youn Kim, Amir F. Kagalwalla Source Type: research