Correlation between hyperinflation defined as an elevated RV/TLC ratio and body composition and cytokine profile in patients with chronic obstructive pulmonary disease.

CONCLUSIONS: Patients with hyperinflation have a lower FFMI, TBW and MMI and a higher proportion of fat tissue. Hyperinflation is associated with elevated concentrations of inflammatory markers what may be associated with more severe disease. Body compositions abnormality and higher activity of systemic inflammation could therefore be a negative prognostic factor in COPD patients.
PMID: 25754053 [PubMed - in process]

Source: Pneumonologia i Alergologia Polska - March 13, 2015 Category: Respiratory Medicine Authors: Rubinsztajn R, Przybyłowski T, Paplińska-Goryca M, Karwat K, Nejman-Gryz P, Chazan R Tags: Pneumonol Alergol Pol Source Type: research